A5049449867- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Pneumonia and Respiratory Infections
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Global Health and Epidemiology
- Influenza Virus Research Studies
- Neonatal Respiratory Health Research
- HIV/AIDS Impact and Responses
- Pneumocystis jirovecii pneumonia detection and treatment
Pfizer (United States)
2019-2025
Pfizer (Canada)
2024-2025
TransCanada (Canada)
2024
ABSTRACT Background RSV detection improves if an additional specimen is collected, but the impact of testing saliva and multiple types has not been assessed. We quantified increase with collection over nasopharyngeal swab (NPS) alone. Methods Prospectively enrolled hospitalized adults aged ≥40 years acute respiratory illness in seven hospitals US Canada had NPS, saliva, sputa, acute/convalescent sera collected tested. Results Among 3,669 participants, 100% 97.7% 33.0% sputum, 33.4% paired...
Abstract Background Case and control definitions may impact VE estimates in observational studies. Using a TND design, we evaluated how influenza vaccine effectiveness against ARI hospitalizations changed when 1) cases were detected through nasopharyngeal swabs (NPS) only versus multiple specimens 2) controls included or excluded other preventable diseases (VPD). Methods Adults aged ≥40 years hospitalized for had NPS saliva sputum tested using Luminex RSV/influenza multiplex PCR assay....
Abstract Background Most epidemiologic studies and clinical testing use a single nasal/nasopharyngeal swab for RSV detection. Previous have documented that detection improves if additional specimen is added to swab, but the impact of using multiple types has not been assessed. We quantified increase in compared nasopharyngeal (NPS) alone. Methods Prospectively enrolled hospitalized adults aged ≥40 years with acute respiratory illness seven hospitals US Canada had NPS, saliva, sputa,...
Adult respiratory syncytial virus (RSV) burden is underestimated due to non-specific symptoms, limited standard-of-care and delayed testing, reduced diagnostic test sensitivity—particularly when using single specimen—when compared children, variable sensitivity based on the upper airway specimen source. We estimated RSV-attributable hospitalization incidence among adults aged ≥ 18 years in Ontario, Canada, a retrospective time-series model-based approach. The Institute for Clinical...
Aim: To assess the burden of respiratory syncytial virus-associated disease in older adults (RSV OA), ≥50 years old, World Health Organization region countries Africa, Americas (except for Canada and USA), Eastern Mediterranean, Europe European Union UK), South-East Asia, Western Pacific Australia, China, Japan, New Zealand, South Korea).