A5068495511- Surfactants and Colloidal Systems
- Inorganic and Organometallic Chemistry
- Plant Stress Responses and Tolerance
- Analytical Chemistry and Chromatography
- Plant nutrient uptake and metabolism
- Plant-Microbe Interactions and Immunity
- Metal complexes synthesis and properties
- Seismic Imaging and Inversion Techniques
- Plant Micronutrient Interactions and Effects
- Insect Resistance and Genetics
- Plant and Fungal Interactions Research
- Seismic Waves and Analysis
- Plant Molecular Biology Research
- Mathematical Analysis and Transform Methods
- CRISPR and Genetic Engineering
- Photochemistry and Electron Transfer Studies
- Chemical Synthesis and Reactions
- Oxidative Organic Chemistry Reactions
- Plant Reproductive Biology
- Antifungal resistance and susceptibility
- Plant tissue culture and regeneration
- Plant Virus Research Studies
- Protein Interaction Studies and Fluorescence Analysis
- Drug Solubulity and Delivery Systems
- Insect and Pesticide Research
Panjab University
2015-2025
Kumaun University
2015-2024
Institute of Management Technology
2021-2024
Institute of Genomics and Integrative Biology
2008-2024
University of Leicester
2024
Nepal Agricultural Research Council
2023
Assam Agricultural University
2020-2023
Kerala Veterinary and Animal Sciences University
2023
Indian Institute of Technology Guwahati
2023
Banaras Hindu University
2004-2022
The clustered, regularly interspaced, short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) system has been used as an efficient tool for genome editing. We report the application of CRISPR-Cas-mediated editing to wheat (Triticum aestivum), most important food crop plant with a very large complex genome. mutations were targeted in inositol oxygenase (inox) phytoene desaturase (pds) genes using cell suspension culture pds gene leaves Nicotiana benthamiana. expression chimeric...
Preface 1. Elementary 1.1. Rate of Reaction 1.2. Constant 1.3. Order and Molecularity 1.4. Equations 1.5. Half-life a 1.6. Zero Reactions 1.7. First 1.8. Radioactive Decay as Phenomenon 1.9. Second 1.10. Third 1.11. Determination 1.12. Experimental Methods Chemical Kinetics Exercises 2. Temperature Effect on 2.1. Derivation Arrhenius Equation 2.2. Energy Activation Factor 2.3. Potential Surface 2.4. Significance 3. Complex 3.1. Reversible 3.2. Parallel 3.3. Consecutive 3.4. Steady-State...
Background Expression of double strand RNA (dsRNA) designed against important insect genes in transgenic plants have been shown to give protection pests through interference (RNAi), thus opening the way for a new generation insect-resistant crops. We earlier compared efficacy dsRNAs/siRNAs, number target genes, growth whitefly (Bemisia tabaci) upon oral feeding. The v-ATPase subunit A (v-ATPaseA) coding gene was identified as crucial target. now report effectiveness tobacco expressing siRNA...
Long non-coding RNAs (lncRNAs) are a family of regulatory that play essential role in the various developmental processes and stress responses. Recent advances sequencing technology computational methods enabled identification characterization lncRNAs certain plant species, but they less known Triticum aestivum (bread wheat). Herein, we analyzed 52 RNA seq data (>30 billion reads) identified 44,698 T. genome, which were characterized comparison to coding sequences (mRNAs). Similar mRNAs,...
Lectin receptor kinases (LRKs) play a critical role in plants during development and stress conditions, but comprehensive analysis at genome level is still not carried out Triticum aestivum. Herein, we performed the wide identification, characterization expression of these genes T. aestivum (TaLRK). In-total 263 TaLRK were identified, which further classified into three groups based on nature lectin domain. We two TaLRKs consisted calcium-dependent (C-LRK), while 84 legume-lectin (L-LRK) 177...
Abstract Sucrose phosphate synthase (SPS; EC 2.4.1.14) and sucrose (SS; 2.4.1.13) are key enzymes in the synthesis breakdown of sugarcane. The activities internodal SPS SS, as well transcript expression were determined using semi‐quantitative RT‐PCR at different developmental stages high low accumulating sugarcane cultivars. activity was higher mature internodes compared with immature all studied However, sugar cultivars showed increased enzyme to stages. SS than cultivars; a similar...
Vitellogenin (Vg) plays vital role in oocytes and embryo development insects. Vg is synthesized the fat body, moves through haemolymph accumulates oocytes. receptors (VgR) present on surface of oocytes, are responsible for transportation from to Here, we cloned characterized these genes Bemisia tabaci Asia1 (BtA1) species. The BtA1Vg BtA1VgR consisted 6,330 5,430 bp long open reading frames, which encoded 2,109 1,809 amino acid (AA) residues protein. protein comprised LPD_N, DUF1943 VWFD...
The leucine rich repeat receptor like kinases (LRRK) constitute the largest subfamily of (RLK), which play critical roles in plant development and stress responses. Herein, we identified 531
This review article briefly describes: (a) the advantages in developing multifunctional nanoparticles for cancer-imaging and therapy, (b) limitations of most porphyrin-based compounds fluorescence imaging photodynamic therapy (PDT), (c) problems associated with current Food Drug Administration (FDA) approved photosensitizers, (d) challenges vivo target-specific PDT agents, (e) development nuclear-imaging agents (PET, SPECT) an option PDT, (f) importance light dosimetry (g) role whole body or...
EBNA3C, one of the Epstein-Barr virus (EBV)-encoded latent antigens, is essential for primary B-cell transformation. Cyclin D1, a key regulator G1 to S phase progression, tightly associated and aberrantly expressed in numerous human cancers. Previously, EBNA3C was shown bind D1 vitro along with A E. In present study, we provide evidence which demonstrates that forms complex cells. Detailed mapping experiments show small N-terminal region lies between amino acids 130–160 binds two different...
DNA-methylation at CpG islands is one of the prevalent epigenetic alterations regulating gene-expression patterns in mammalian cells. Hypo- or hypermethylation-mediated oncogene activation, tumor suppressor gene (TSG) silencing mechanisms, widely contribute to development multiple human cancers. Furthermore, oncogenic viruses, including Epstein-Barr virus (EBV)-associated cancers, were also shown be influenced by modifications on viral and cellular genomes infected We investigated EBV...
ABSTRACT The DNA damage response (DDR) of host cells is utilized by a number viruses to establish and propagate their genomes in the infected cells. We examined expression DDR genes during Kaposi's sarcoma-associated herpesvirus (KSHV) infection human peripheral blood mononuclear (PBMCs). were mostly downregulated, except H2AX, which was upregulated infection. H2AX important for gammaherpesvirus infectivity, its phosphorylation at serine 139 crucial maintenance latency mouse...
The Ca2+/cation antiporters (CaCA) superfamily proteins play vital function in Ca2+ ion homeostasis, which is an important event during development and defense response. Molecular characterization of these has been performed certain plants, but they are still not characterized Triticum aestivum (bread wheat). Herein, we identified thirty four TaCaCA proteins, were classified into TaCAX, TaCCX, TaNCL TaMHX protein families based on their structural organization evolutionary relation with...