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Joshua Bambrick

ORCID: 0009-0003-3908-0722
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A5096909571
Research Areas
  • Protein Structure and Dynamics
  • Machine Learning in Bioinformatics
  • Computational Drug Discovery Methods
 Accurate structure prediction of biomolecular interactions with AlphaFold 3
OPENALEX - Publications 
Josh Abramson Jonas Adler Jack Dunger Richard Evans Tim Green and 43 more Alexander Pritzel Olaf Ronneberger Lindsay Willmore Andrew J. Ballard Joshua Bambrick Sebastian W. Bodenstein David A. Evans Chia-Chun Hung Michael O’Neill David Reiman Kathryn Tunyasuvunakool Zachary Wu Akvilė Žemgulytė Eirini Arvaniti Charles Beattie Ottavia Bertolli Alex Bridgland Alexey V. Cherepanov Miles Congreve Alexander I. Cowen-Rivers Andrew Cowie Michael Figurnov Fabian B. Fuchs Hannah Gladman Rishub Jain Yousuf A. Khan Caroline M. R. Low Kuba Perlin Anna Potapenko Pascal Savy Sukhdeep Singh Adrian Stecuła Ashok Thillaisundaram Catherine Tong Sergei Yakneen Ellen D. Zhong Michał Zieliński Augustin Žídek Victor Bapst Pushmeet Kohli Max Jaderberg Demis Hassabis John Jumper

Abstract The introduction of AlphaFold 2 1 has spurred a revolution in modelling the structure proteins and their interactions, enabling huge range applications protein design 2–6 . Here we describe our 3 model with substantially updated diffusion-based architecture that is capable predicting joint complexes including proteins, nucleic acids, small molecules, ions modified residues. new demonstrates improved accuracy over many previous specialized tools: far greater for protein–ligand...

10.1038/s41586-024-07487-w article EN cc-by Nature 2024-05-08
 Addendum: Accurate structure prediction of biomolecular interactions with AlphaFold 3
OPENALEX - Publications 
Josh Abramson Jonas Adler Jack Dunger Richard Evans Tim Green and 43 more Alexander Pritzel Olaf Ronneberger Lindsay Willmore Andrew J. Ballard Joshua Bambrick Sebastian W. Bodenstein David A. Evans Chia-Chun Hung Michael O’Neill David Reiman Kathryn Tunyasuvunakool Zachary Wu Akvilė Žemgulytė Eirini Arvaniti Charles Beattie Ottavia Bertolli Alex Bridgland Alexey V. Cherepanov Miles Congreve Alexander I. Cowen-Rivers Andrew Cowie Michael Figurnov Fabian B. Fuchs Hannah Gladman Rishub Jain Yousuf A. Khan Caroline M. R. Low Kuba Perlin Anna Potapenko Pascal Savy Sukhdeep Singh Adrian Stecuła Ashok Thillaisundaram Catherine Tong Sergei Yakneen Ellen D. Zhong Michał Zieliński Augustin Žídek Victor Bapst Pushmeet Kohli Max Jaderberg Demis Hassabis John Jumper

10.1038/s41586-024-08416-7 article EN cc-by Nature 2024-11-27
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