A5064249096- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Reproductive Physiology in Livestock
- Corneal Surgery and Treatments
- dental development and anomalies
- Effects of Environmental Stressors on Livestock
- Testicular diseases and treatments
- Developmental Biology and Gene Regulation
- Animal Genetics and Reproduction
- Cancer Mechanisms and Therapy
- Vector-Borne Animal Diseases
- PI3K/AKT/mTOR signaling in cancer
- Plant Reproductive Biology
- Hedgehog Signaling Pathway Studies
- Semiconductor Quantum Structures and Devices
- Veterinary Equine Medical Research
- Ocular Disorders and Treatments
- Angiogenesis and VEGF in Cancer
- Bone Metabolism and Diseases
- Cancer-related gene regulation
- Advanced biosensing and bioanalysis techniques
- Metallurgy and Material Forming
- Fibroblast Growth Factor Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Disease Management and Epidemiology
University of East Anglia
2023
Mount Saint Vincent University
2018-2021
University of Guelph
2009-2017
The ultrasonographic image of an organ is a product scattering and reflection high-frequency ultrasound beams by discrete units tissue. number acoustic tissue interfaces vascularity affects the quantitative characteristics grey-scale images. This study was undertaken to examine influences scrotal/testicular integument blood flow on testicular echotexture parameters in ram. Serial images were obtained during surgical castration 7 Rideau Arcott rams aged 20-22 weeks. first 2 sets taken through...
Breeding soundness evaluation (BSE) is the primary assessment for determining reproductive potential of male animals. This method, however, cannot be used to evaluate semen frequently or predict future quality. Computerized analysis ultrasonographic images provides information on histophysiological changes in organs. We hypothesized that: (i) parameters would correlate with characteristics distal region (cauda) epididymis and (ii) testicular ultrasound and/or circulating testosterone...
The onset of spermatogenesis during prepubertal development is accompanied by dynamic changes in testicular microstructure. Computer-assisted analysis scrotal ultrasonograms may allow us to track these a noninvasive manner; however, the echotextural characteristics different histomorphological variables remain unclear. Hence objective this study was compare and microscopic attributes testis over first wave prepubescent ram lambs. Bi-weekly ultrasound examinations weekly biopsies were carried...
Cancerous cells are characterised by their ability to invade, metastasise, and induce angiogenesis. Tumour use various molecules that can be targeted reverse these processes. Dasatinib, a potent Src inhibitor, has shown promising results in treating hepatocellular carcinoma (HCC) vitro vivo. However, its effectiveness is limited focal adhesion kinase (FAK) activation. Isothiocyanates, on the other hand, phytochemicals with broad anticancer activity FAK inhibition capabilities. This study...
Testicular echotextural attributes are closely associated with spermatogenic development; however, precise characterisation of specific germ cell types is difficult due to tremendous heterogeneity. Recently, retinoic acid (RA) administration in neonatal mice was found induce highly synchronised spermatogenesis as adults. A RA-treatment protocol tested 17 ram lambs treated or without RA at 8 weeks age, scrotal ultrasonography and blood samples collected until castration 24h 2.5 later. At 8.2...
The anterior portion of the eye in birds is supported by a ring bony elements within sclera, constituting scleral ossicles. These intramembranous bones are induced series transient papillae overlying conjunctival epithelium during embryonic development. A well‐defined spatiotemporal pattern formation followed, resulting complete circle 13–16 evenly‐spaced per chicken embryo. regular distribution and variable number this system give it strong similarity to other reaction‐diffusion models...
The conjunctival epithelium of the chicken eye develops a series placodes beginning at embryonic day 6.5. These develop into papillae over course 1.5 days before disappearing. transient structures are responsible for inducing underlying mesenchyme to ring scleral ossicles. Here we assess gene expression patterns five major signaling pathways known be involved in development other epithelial appendages, namely WNT/β‐catenin, bone morphogenetic protein (BMP), ectodysplasin (EDA), fibroblast...
Developmental induction is the cornerstone of many developmental processes, with research most often focused on identifying inductive factors and/or tissues. Here, we examine microenvironment that enables events occur during development scleral ossicles. The ossicle system avians composed a series 13-16 flat neural-crest derived overlapping bones situated in sclera eye. skeletogenic condensations, preceding these bones, develop over two day period and are induced by placode-derived...