A5103860366- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Hearing, Cochlea, Tinnitus, Genetics
- Neuroinflammation and Neurodegeneration Mechanisms
- Wound Healing and Treatments
- Neuroscience and Neuropharmacology Research
- Medical Imaging and Analysis
- Scoliosis diagnosis and treatment
- Polysaccharides and Plant Cell Walls
- Microbial Community Ecology and Physiology
- Anesthesia and Neurotoxicity Research
- Hearing Loss and Rehabilitation
- Prostate Cancer Diagnosis and Treatment
- Vestibular and auditory disorders
- Cerebrovascular and Carotid Artery Diseases
- MicroRNA in disease regulation
- Osteoarthritis Treatment and Mechanisms
- Air Quality Monitoring and Forecasting
- Polysaccharides Composition and Applications
- Hip and Femur Fractures
- RFID technology advancements
- Acute Ischemic Stroke Management
- Prostate Cancer Treatment and Research
- Neurogenesis and neuroplasticity mechanisms
- Neurological Disease Mechanisms and Treatments
Yancheng Third People's Hospital
2023-2025
Shandong Institute of Metrology
2024
Zhengzhou University
2024
Qingdao Institute of Bioenergy and Bioprocess Technology
2022-2024
Lanzhou University of Technology
2020-2024
Chinese Academy of Sciences
2022-2024
Zhejiang University
2021-2024
First Affiliated Hospital Zhejiang University
2021-2024
Zhejiang Provincial People's Hospital
2010-2021
Hangzhou Medical College
2019-2021
IFN-β is induced via a c-fos dependent mechanism that present downstream of the receptor activator NF-κB ligand (RANKL)-RANK signal transduction cascade during osteoclast differentiation. Increased production in turn inhibits osteoclastogenesis. However, by which exerts its suppressive function remains unclear. In study, we found miR-155, an IFN-β-induced miRNA, mediated effect on differentiation targeting SOCS1 and MITF, two essential regulators These findings have not only demonstrated...
Because of the limitation in treatment window r-tPA (recombinant tissue-type plasminogen activator), development delayed for stroke is needed. In this study, we examined efficacy poststroke (post 3-8 days) sonic hedgehog pathway agonist on functional recovery and underlying mechanisms.We evaluated at 1 month after using locomotion analysis Barnes maze test cognitive function. We used a genetically inducible neural stem cell-specific reporter mouse line (nestin-CreERT2-R26R-YFP) to label...
Anterior gradient protein 2 (AGR2) has been reported as a novel biomarker with potential oncogenic role. However, its association the prognosis and survival rate of gastric cancer (GC) not yet determined. Therefore, present study aimed to examine expression prognostic significance AGR2 in patients GC. Immunohistochemistry was used analyze cathepsin D (CTSD) 436 clinicopathologically characterized GC cases 92 noncancerous tissue samples. CTSD were both elevated lesions compared tissues. In...
Abstract The pollution caused by PM 2.5 can have serious consequences for human health and the environment, making timely prediction of its concentration important. This study proposes a Spatial-Temporal Air quality Transformer (STAFormer) forecasting concentration. In dimension time, this designs novel multi-head attention mechanism that discover multi-periodicity in time series, thereby extracting more complex temporal features. terms spatial analysis, graph convolutional neural network...
We intended to investigate the potential of several transitional zone (TZ) volume-related variables for detection clinically significant prostate cancer (csPCa) among lesions scored as Prostate Imaging Reporting and Data System (PI-RADS) category 3. Between September 2018 August 2023, patients who underwent mpMRI examination PI-RADS 3 were queried from our institution. The diagnostic performances prostate-specific antigen density (PSAD), TZ-adjusted PSAD (TZPSAD), TZ-ratio (TZ volume/whole...
Cholinergic synapses in the cochlear nucleus (CN) have been reported to modulate spontaneous activity via muscarinic acetylcholine receptors. In this study, receptor binding was measured as specific of 1-[N-methyl-(3)H]scopolamine CN regions control rats and 7 days, 1 month, 2 months after unilateral ablation. rats, strongest found granular regions, followed order by fusiform soma, molecular, deep layers dorsal (DCN), with much lower anteroventral (AVCN) posteroventral (PVCN). After...
This was a prospective, randomized controlled clinical study.To determine the efficacy of absorbable gelatin sponge in reducing blood loss, as well shortening length hospital stay patients undergoing multilevel posterior lumbar spinal surgery.Absorbable is reported to decrease postoperative drain output and after cervical spine surgery. However, there dearth literature on prospective study surgery.A total 82 consecutive who underwent fusion or interbody between June 2011 2012 were...
Abstract Air pollution is closely intertwined with public health. However, air quality forecasting a very challenging project, and the influencing factors are intertwined. This study focuses on analyzing urban from spatiotemporal perspective, based various that affect quality. In this paper, diverse dataset impacting was collected, including pollutant concentrations, meteorological conditions, traffic flow data. A GCN-LSTM model developed to thoroughly explore spatial relationships between...
Ischemia-reperfusion (IR) injury is associated with neurological disorders such as stroke. The therapeutic potential of human umbilical cord mesenchymal stem cells (hUC-MSCs) and their secreted extracellular vesicles (EVs) in alleviating IR across various cell types including neuronal has been documented. However, the underlying mechanisms through which hUC-MSCs hUC-MSC-EVs protect from IR-triggered damage are not well understood. In this study, we co-cultured SH-SY5Y neuroblastoma or...
Using microdissection and quantitative microassay, choline acetyltransferase (ChAT) activity was mapped in the cochlear nucleus (CN) source nuclei of olivocochlear bundle, lateral superior olive ventral trapezoid body. In control rats, gradients ChAT were found within major subdivisions CN olive. These correlated with known tonotopic organizations, higher activities corresponding to locations representing sound frequencies. No gradient rats surviving 7 days or 1 2 months after ablation,...
Objective To assess the clinical efficacy and share technique notes of Wiltse Approach TLIF for treating single segment degenerative lumbar spinal disease. Method In this retrospective controlled study, 780 patients with disease who were operated in our hospital from January 2016 to December 2020 analyzed retrospectively. The randomly assigned approach group (group A, 410 cases) conventional open B, 370 cases). Patient's assessment pain disability evaluated by visual analogue scale (VAS)...
Abstract Background This study aimed to reveal the associations of osteoporotic vertebral compression refracture (OVCRF) incidence with sarcopenia and paravertebral muscles (PVM). Methods A total 214 elderly patients who underwent percutaneous kyphoplasty in our hospital between January 2017 December 2019 were analyzed. Data on possible risk factors, including sex, age, weight, height, diabetes, treated levels (thoracolumbar junction [(T10–L2]), vacuum clefts, body mass index (BMI),...
In this study, the extraction conditions ofNostoc communeVauch polysaccharide (NCVP) were optimized by single factor and orthogonal experiments. Then, NCVP microcapsules (NCVPM) prepared. After analyzing microcapsule structural thermal characteristics, skin wound healing ability was studied establishing back trauma rat models. Results showed that yield 10.37% under following optimum conditions: 210 min time, solid-liquid ratio of 1:50 temperature 90 °C. The overall performance best when...
Objective: Although cerebral ischemia can activate endogenous reparative processes, such as proliferation of neural stem cells (NSCs) in the subventricular zone (SVZ) and subgranular (SGZ), majority these new die shortly after injury do not appropriately differentiate into neurons, or migrate functionally integrate brain. The purpose this study was to examine a novel strategy for treatment stroke by optimizing survival ischemia-induced NSCs SVZ SGZ. Methods: Adult SGZ were grown neurospheres...