A5057247924- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Spinal Fractures and Fixation Techniques
- Nanoplatforms for cancer theranostics
- Spinal Hematomas and Complications
- Nerve Injury and Rehabilitation
- Scoliosis diagnosis and treatment
- Hippo pathway signaling and YAP/TAZ
- Nanoparticle-Based Drug Delivery
- Tendon Structure and Treatment
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Cancer, Lipids, and Metabolism
- Obesity, Physical Activity, Diet
- Nerve injury and regeneration
- Bone Metabolism and Diseases
- Spinal Cord Injury Research
- Physical Activity and Health
- Cancer, Hypoxia, and Metabolism
- Musculoskeletal pain and rehabilitation
- NF-κB Signaling Pathways
- Ferroptosis and cancer prognosis
- RNA Interference and Gene Delivery
- Birth, Development, and Health
Hangzhou Medical College
2022-2024
Zhejiang Provincial People's Hospital
2015-2024
The authors describe the outcomes of 25 patients, procedure's surgical steps, and potential advantages using posterior percutaneous full-endoscopic cervical discectomy under local anesthesia. They believe this technique may be a new alternative in treatment selected patients with radiculopathy due to soft-disc herniation.
Cancer immunotherapy is a treatment method that activates or enhances the autoimmune response of body to fight tumor growth and metastasis, has fewer toxic side effects longer-lasting efficacy than radiotherapy chemotherapy, become an important means for clinical cancer. However, results from have shown most patients lack responsiveness cannot benefit this strategy. The microenvironment (TME) plays critical role in immunotherapy. TME typically prevents effective lymphocyte activation,...
Abstract Tendinopathy is a common tendon disorder characterized by pain, swelling, and dysfunction. Current evidence has demonstrated that the depletion of stem cell pool non-tenogenic differentiation tendon-derived stem/progenitor cells (TSPCs) might account for pathogenesis tendinopathy. FNDC5/Irisin, as novel exercise-induced myokine, proved to be involved in protective effects on musculoskeletal disorders. However, whether irisin can affect TSPCs fate still unknown. To ascertain roles...
Hepatocellular carcinoma (HCC) remains a global challenge as it is the sixth most common neoplasm worldwide and third leading cause of cancer-related death. A key feature HCC abnormal metabolism, which promotes cancer cell proliferation, survival, invasion, metastasis. However, significance metabolism-related genes (MRGs) in to be elucidated. Here, we aim establish novel prognostic signature for prediction patient outcomes investigate value MRG expression HCC. In our research,...
To evaluate the feasibility and efficacy of computed tomography (CT)-guided radiofrequency ablation (RFA) cervical intervertebral discs for treatment discogenic cervicogenic headache (CEH).Some patients with CEH experience no obvious therapeutic effect after conventional therapy, particularly refractory originating from abnormal discs. Treatment this type remains poorly characterized.Using a single intervention arm, pretest/posttest design, we retrospectively analyzed data who underwent...
<title>Abstract</title> The purpose of this study was to evaluate the clinical effect percutaneous posterior full-endoscopic cervical foraminotomy and discectomy (PECFD) for treating degenerative diseases adjacent segments in patients who have undergone anterior decompression fusion(ACDF). <bold>Method</bold>: A retrospective observational performed between July 2021 November 2023 on all treated with PECFD segment disease (ASD) after ACDF. Clinical outcomes were assessed using a visual...
Sinuvertebral nerve overactivation is one of the mechanisms neck pain caused by cervical disc herniation. Radiofrequency ablation (RFA) sinuvertebral nerves has shown efficacy for treatment discogenic low back pain. However, relatively few studies evaluated RFA chronic Clinical data were retrospectively collected from 168 patients diagnosed with herniated January 1, 2019, to September 2022, who treated computed tomography (CT)-guided at Pain Medicine Center Zhejiang Provincial People's...
Background Extracellular matrix (ECM) degradation, chondrocyte inflammation, and cellular senescence contribute to the pathology of osteoarthritis (OA). Empagliflozin, a selective inhibitor sodium-glucose cotransporter-2 (SGLT2), has been reported show anti-inflammatory properties in several conditions. However, whether empagliflozin can be used improve OA is still unknown. Methods The protective effects underlying mechanism were investigated vitro vivo. Cell viability, catabolic markers,...
Aim: To explore the long-term outcome of patients with lumbar disc herniation (LDH) performed percutaneous transforaminal endoscopic discectomy technique (PTED). Materials and methods: In this retrospective study, we collected medical records from 974 LDH who received PTED operation May 2010 to July 2015. Follow-up measurements were at 1, 3, 6 12 months after surgery. Before surgery, visual analogue scale (VAS) was used for evaluating pain in leg low back. Oswestry Disability Index (ODI)...
Abstract Purpose: Although percutaneous minimally invasive techniques have been gradually applied to the surgical treatment of cervical disc herniation (CDH), some patients still experience adverse outcomes. The aim this study was explore effect acupuncture for CDH after surgery (MIS). Methods: We retrospectively reviewed with admitted our department between January 1, 2019 and December 31, 2020. Visual analog scale (VAS), neck disability index (NDI), modified MacNab criteria were used...