Lingxu Li

ORCID: 0009-0003-6952-0127
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Research Areas
  • Infectious Diseases and Mycology
  • Microbial infections and disease research
  • Cardiac Ischemia and Reperfusion
  • Bacteriophages and microbial interactions
  • Vector-borne infectious diseases
  • Traditional Chinese Medicine Analysis
  • Glycosylation and Glycoproteins Research
  • Traditional Chinese Medicine Studies
  • Healthcare and Venom Research
  • Inhalation and Respiratory Drug Delivery
  • Herpesvirus Infections and Treatments
  • Stroke Rehabilitation and Recovery
  • Lipid metabolism and disorders
  • Botulinum Toxin and Related Neurological Disorders
  • Veterinary Oncology Research
  • Insect and Pesticide Research
  • Nanoparticle-Based Drug Delivery
  • Acute Ischemic Stroke Management
  • Oral and Maxillofacial Pathology
  • Insect Pest Control Strategies

Nanjing Agricultural University
2022-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025

Changchun University of Chinese Medicine
2024

Introduction: Qilong capsule (QC) has been used clinically to treat ischemic stroke in China. This study evaluated the therapeutic effects of QC on myocardial ischemia-reperfusion injury (MIRI) and its potential mechanisms. Method: The components candidate targets against MIRI were predicted by network pharmacology via relevant databases such as TCMSP, BATMAN-TCM, GeneCards. mechanisms Gene Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) pathway enrichment analyses verified...

10.2174/0113862073332431241120044411 article EN Combinatorial Chemistry & High Throughput Screening 2025-01-10

Abstract Introduction Enzootic nasal adenocarcinoma (ENA) is a cancer that occurs in goats and sheep infected by enzootic tumour virus. Pathologic examinations are useful for distinguishing tumours from inflammatory hyperplasia. The aim of this study was to describe the pathological characteristics ENA. Material Methods Caprine samples were collected examination. tissue sections stained with haematoxylin-eosin periodic acid-Schiff (PAS) processed immunohistochemical staining. Tumour also...

10.2478/jvetres-2025-0010 article EN cc-by-nc-nd Journal of Veterinary Research 2025-03-01

Lymphography is a useful technique in the diagnosis of lymphatic diseases. Conventional lymph node imaging methods, such as subcutaneous and footpad injections, are invasive unable to visualize mesenteric nodes. Liposomes have potential increase oral bioavailability poorly bioavailable hydrophilic drugs promote their transport intestinal lymph. In this study, iohexol liposome was prepared using cholesterol, soybean lecithin, by reverse-phase evaporation method. It had an encapsulation...

10.1080/08982104.2025.2473327 article EN Journal of Liposome Research 2025-03-08

The aim of this study was to describe radiography, computed tomography (CT), and magnetic resonance imaging (MRI) findings enzootic nasal tumors in goats infected with tumor viruses. Five six a mean age 2 years, showed clinical signs respiratory disease. Head radiographs increased density the unilateral or bilateral cavity four goats, CT scan that space-occupying lesion originated from ethmoid bone enhanced homogeneously postcontrast all goats. concha destroyed paranasal sinus mucosa...

10.3389/fvets.2022.810977 article EN cc-by Frontiers in Veterinary Science 2022-03-11

Enzootic nasal adenocarcinoma (ENA) is a contagious tumor disease of goats and sheep, which caused by enzootic virus (ENTV). To better understand the pathogenesis ENA, this study aimed to establish goat ENA cell line (ENA-1). The cells have been characterized with regard morphology, growth rate, ultrastructural features, chromosome number, expression CK7 CK18, tumorigenicity, species, mycoplasma contamination. ENA-1 had an epithelioid morphology unstable number under light microscope. Under...

10.3390/vetsci11060260 article EN cc-by Veterinary Sciences 2024-06-07

Background Post-stroke spasticity (PSS) is a common complication after stroke and an important cause of high rates disability stroke. At present, modern medicine has made great progress in the treatment PSS, ‘early detection, early treatment’ become general consensus for PSS clinic. Clarifying risk factors can help to detect treat functional disorders caused by at earlier stage. Methods This retrospective study. 436 patients who visited Neurology Department Third Affiliated Clinical Hospital...

10.3389/fneur.2024.1478206 article EN cc-by Frontiers in Neurology 2024-12-17

Dried blood spot (DBS) based PCR was considered an inexpensive and feasible method for detecting pathogens in the blood. The DBS carrier filter paper kits are crucial accurate diagnosis. We evaluated 4 types of papers 20 samples. Plasmodium results showed that minimum detection limit 1 × 102 parasites/μL, positive rates ranged from 0% to 100%. were satisfactory falciparum (P. falciparum) Plasmodium. vivax vivax) archived samples Babesia gibsoni (B. gibsoni) fresh pet Our provided a useful...

10.1155/2022/5715436 article EN cc-by Journal of Tropical Medicine 2022-08-13

New antibabesial drugs are required to fight resistant parasites, and plant-derived natural products a robust source. Six kinds of product extracts derived from herbal medicines that traditionally used for the treatment malaria were selected test effect on Babesia gibsoni in vitro vivo. Parasitized blood was collected dogs infected with B. evaluate inhibitory verbenalin, catechin hydrate, dihydrolycorine, embelin, ursolic acid, agrimol B, bruceine H vitro. The expression levels 18S rRNA gene...

10.1645/21-108 article EN Journal of Parasitology 2022-07-22
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