A5019575848- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Antibiotic Resistance in Bacteria
- Bacteriophages and microbial interactions
- Salmonella and Campylobacter epidemiology
- ATP Synthase and ATPases Research
- Microbial Community Ecology and Physiology
- Vibrio bacteria research studies
- Drug Transport and Resistance Mechanisms
- Viral gastroenteritis research and epidemiology
- Infant Nutrition and Health
- Trace Elements in Health
- Cancer Research and Treatments
University of Georgia
2021-2025
Indiana University School of Medicine
2018
Wenzhou Medical University
2018
Indiana University – Purdue University Indianapolis
2018
ABSTRACT Campylobacter jejuni is a common foodborne pathogen worldwide that associated with high rates of morbidity and mortality among infants in low- to middle-income countries (LMICs). Human milk provides an important source nutrients contains antimicrobial components for protection against infection. However, recent studies, including our own, have found significantly higher levels diarrheal stool samples collected from breastfed compared non-breastfed LMICs. We hypothesized C. has...
Little is known about how Borrelia burgdorferi, the Lyme disease pathogen, adapts and survives in tick vector. We previously identified a bacterial CarD N-terminal-like (CdnL) protein, LtpA (BB0355), B. burgdorferi that preferably expressed at lower temperatures, which surrogate condition mimicking portion of enzootic cycle burgdorferi. CdnL-family proteins, an emerging class RNAP-interacting transcription factors, are essential for viability Mycobacterium tuberculosis Myxococcus xanthus....
Bacteriophages (phages) are predicted to be the most ubiquitous biological entity on earth, and yet, there still vast knowledge gaps in our understanding of phage diversity phage-host interactions. Approximately one hundred Acinetobacter-infecting DNA viruses have been identified, this report, we describe eight more. We isolated two typical dsDNA lytic podoviruses (CAP1-2), five unique dsRNA cystoviruses (CAP3-7), lysogenic siphovirus (SLAP1), all capable infecting multidrug resistant...
In this study, we identify a separate role for the Campylobacter jejuni l-fucose dehydrogenase in chemotaxis and demonstrate that mechanism is not only limited to C. but also present Burkholderia multivorans. We now hypothesize energy taxis may contribute reduction of l-fucose-metabolizing strains from gastrointestinal tract breastfed infants, selecting isolates with increased colonization potential.