A5114888802- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis and biological activity
- Organophosphorus compounds synthesis
- Crystal structures of chemical compounds
- Synthesis of heterocyclic compounds
- Synthesis and Biological Evaluation
- Synthesis and characterization of novel inorganic/organometallic compounds
- Enzyme function and inhibition
- Phenothiazines and Benzothiazines Synthesis and Activities
- Click Chemistry and Applications
- Structural and Chemical Analysis of Organic and Inorganic Compounds
Tunis University
1999-2024
Tunis El Manar University
2008-2024
Laboratoire de Synthèse Organique
2008
Reaction of iminoesters 1 with sulfonyl isocyanates gave the corresponding sulfonamide imidates 2. The cyclocondensation latter a series hydrazine in methanol affords new functionalized triazoles high yields.Simple nitrogen-containing heterocycles attached to sulfonamido moieties have received large amount attention literature, as consequence their exciting biological properties and role pharmacophores considerable historical importance.Heterocyclic sulfonamides are used carbonic anhydrase...
In the title compound, C(15)H(12)N(4)S, benzimidazole ring is essentially planar, with a mean deviation of 0.0082 (1) Å from least-squares plane defined by nine constituent atoms. crystal, inversion dimers linked pairs C-H⋯N hydrogen bonds occur.
In this work, we report the synthesis and characterization of a new condensed aromatic heterocycle (1-(2-chloroquinolin-3-yl)-N-(4-fluorobenzyl)methanimine) useful in various fields, mainly medicinal therapeutic chemistry, with interesting biological properties. Characterization title compound was carried out by 1H, 13C, 19F nuclear magnetic resonance X-ray diffraction techniques. The crystal structure reveals that crystallizes monoclinic system data for C17H12ClFN2: monoclinic, space group...
In the title compound, 2-[(4-benz-hydryl-piperazin-1-yl)-methyl]-acrylo-nitrile, C(21)H(23)N(3), substituted piperazine ring adopts a chair conformation and dihedral angle between mean planes of aromatic rings is 71.61 (8)°.
Several bis(α-aminophosphonates) have been conveniently prepared in good yields using a straightforward multicomponent Kabachnik-Fields reaction between ethane 1,2-diamine or propane 1,3-diamine, diethylphosphite and aldehydes under catalyst-free conditions. The nucleophilic substitution of ethyl (2-bromomethyl)acrylate mild conditions afforded an original synthetic approach to new series bis(allylic-α-aminophosphonates).
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