Xabier Jiménez-Aberásturi

ORCID: 0000-0003-2824-3445
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About
Contact & Profiles
Research Areas
  • Crystallization and Solubility Studies
  • Catalytic C–H Functionalization Methods
  • X-ray Diffraction in Crystallography
  • Sulfur-Based Synthesis Techniques
  • Catalytic Alkyne Reactions
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Click Chemistry and Applications
  • Chemical Synthesis and Reactions
  • Organophosphorus compounds synthesis
  • Cyclopropane Reaction Mechanisms

University of the Basque Country
2021-2023

A previously unprecedented azo-Povarov reaction between N-carbonyl aryldiazenes and trans-cyclooctene derivatives has been developed. The participation of these in the uncatalyzed [4 + 2] cycloaddition enabled the...

10.1039/d5ob00508f article EN cc-by-nc Organic & Biomolecular Chemistry 2025-01-01

We disclose the first accomplishment of azo-Povarov reaction involving Sc(OTf)3-catalyzed [4 + 2] annulations N-carbonyl aryldiazenes with cyclopentadiene in chloroform, which act as 4π-electron donors. Hence, this protocol offers a rapid access to an array cinnoline derivatives moderate good yields for substrates over wide scope. The synthetic potential was achieved by gram-scale and further derivatization obtained polycyclic product.

10.1021/acs.joc.2c01224 article EN cc-by The Journal of Organic Chemistry 2022-08-16

The use of MW allows the efficient palladium(II)-catalysed C-3 acylation thiophenes with aldehydes via C(sp2)-H activation for synthesis (cyclo)alkyl/aryl thienyl ketones (43 examples). Compared to standard thermal conditions, reduces reaction time (15 30 min vs. 1 3 hours), leading improved yields (up 92%). control positional selectivity is achieved by 2-pyridinyl and 2-pyrimidyl ortho-directing groups at C-2 thiophene scaffold. To show synthetic applicability, selected were subjected...

10.1039/d1ob02176a article EN Organic & Biomolecular Chemistry 2021-12-22

Several bis(α-aminophosphonates) have been conveniently prepared in good yields using a straightforward multicomponent Kabachnik-Fields reaction between ethane 1,2-diamine or propane 1,3-diamine, diethylphosphite and aldehydes under catalyst-free conditions. The nucleophilic substitution of ethyl (2-bromomethyl)acrylate mild conditions afforded an original synthetic approach to new series bis(allylic-α-aminophosphonates).

10.3390/molecules28124678 article EN cc-by Molecules 2023-06-09
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