- Parkinson's Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Biotin and Related Studies
- Olfactory and Sensory Function Studies
- RNA regulation and disease
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
Nanfang Hospital
2023
Southern Medical University
2020-2023
Zhujiang Hospital
2020
Abstract Objective We aimed to identify key susceptibility gene targets in multiple datasets generated from postmortem brains and blood of Parkinson’s disease (PD) patients healthy controls (HC). Methods performed a multitiered analysis integrate the expression data using multiple-gene chips 244 human tissues. identified hub node genes highly PD-related consensus module by constructing protein–protein interaction (PPI) networks. Next, we validated top four interacting 238 subjects (90...
Abstract Olfactory tests are used for the evaluation of ability to detect and identify common odors in humans psychophysically. currently administered by professionals with a set given odorants. Manual administration such can be labor cost intensive data collected as confounded experimental variables, which adds personnel costs introduces potential errors variability. For large-scale longitudinal studies, manually recorded must compiled from multiple sites. It is difficult standardize way...
Objective: We aimed to identify key susceptibility gene targets in multiple datasets generated from post-mortem brains of Parkinson’s disease (PD) patients and healthy controls (HC). Methods: performed a multi-tiered analysis integrate the expression data using multiple-gene chips 244 human post mortem tissues. identified hub node genes highly PD-related consensus module by constructing protein-protein interaction (PPI) networks. Next we validated top four interacting 238 subjects (90...