A5036119470- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Nerve injury and regeneration
- Hydrogels: synthesis, properties, applications
- Mental Health Research Topics
- Nanoplatforms for cancer theranostics
- RNA Interference and Gene Delivery
- Antimicrobial Peptides and Activities
- Tissue Engineering and Regenerative Medicine
- Sleep and related disorders
- Graphene and Nanomaterials Applications
- COVID-19 and Mental Health
Nantong University
2020-2022
Nantong Science and Technology Bureau
2020
Abstract Easy cancer recurrence and wound infections have been clinical challenges after surgical treatment of melanoma. Herein, a silk‐inspired in situ gelation system containing methacrylated silk fibroin (SF) chlorine e6 for improved therapy with enhanced healing is developed. Favored by the macrophage recruitment capacity SF hydrogel, promising antitumor immune responses can be turned “on” via near infrared irradiation controllable manner to achieve combination photodynamic significantly...
By combination of alginate/polyacrylamide/chitosan, tough antibacterial hydrogels are designed for applications as tissues adhesives to promote wound healing.
A lack of effective bioactivity to create a desirable microenvironment for peripheral nerve regeneration has been challenging in successful treatment long-distance injuries using guidance conduits (NGCs) clinically. Herein, we developed silk-inspired phototriggered gelation system combining dual therapeutic cues anisotropic topography and adhesive ligands improving regeneration. Importantly, enhanced cell recruitment myelination Schwann cells were successfully achieved by the Arg-Gly-Asp...
Abstract Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is key to accelerate regeneration. Herein, pure silk fibroin (SF) hydrogel with combination high-strength and aligned microgrooved topographic structure reported. The hydrogels exhibit excellent mechanical properties high strength. Good biocompatibility also allows support cell survival. Significantly, structures enables Schwann cells. Moreover, holds strong capacity for...
Abstract Objective We evaluated the change in mental health and sleep quality of college students at four time periods. Methods Mental status were using Pittsburgh Sleep Quality Index (PSQI) Symptom Checklist-90-Revised (SCL-90-R) questionnaire across Psychology interventions carried out from third period. Results Students period had higher PSQI total scores [mean (SD), 6.01 (3.27)] than those first [5.60 (3.11)], second [4.17 (2.10)] fourth [4.09 (2.80)]. After adjustment for covariates...