A5019260923- Neurotransmitter Receptor Influence on Behavior
- Receptor Mechanisms and Signaling
- Neuroscience and Neuropharmacology Research
- Nicotinic Acetylcholine Receptors Study
- Neuroendocrine regulation and behavior
- Adenosine and Purinergic Signaling
- Cannabis and Cannabinoid Research
- Treatment of Major Depression
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Psychedelics and Drug Studies
- Olfactory and Sensory Function Studies
- Neurological disorders and treatments
- Biochemical Analysis and Sensing Techniques
- Parkinson's Disease Mechanisms and Treatments
- Attention Deficit Hyperactivity Disorder
- Organic Light-Emitting Diodes Research
- Chemical synthesis and alkaloids
- Organic Electronics and Photovoltaics
- Nerve injury and regeneration
- Pharmacological Receptor Mechanisms and Effects
- Diet and metabolism studies
- Functional Brain Connectivity Studies
- Sleep and Wakefulness Research
- Neural and Behavioral Psychology Studies
Yale University
2015-2025
Quinnipiac University
2023
Vanderbilt University
2023
John F. Kennedy Center for the Performing Arts
2023
University of Connecticut
2009-2015
Mesolimbic dopamine (DA) is involved in behavioral activation and effort-related processes. Rats with impaired DA transmission reallocate their instrumental behavior away from food-reinforced tasks high response requirements, instead select less effortful food-seeking behaviors. In the present study, effects of several drug treatments were assessed using a progressive ratio (PROG)/chow feeding concurrent choice task. With this task, rats can lever press on PROG schedule reinforced by...
Motivated behaviors are often characterized by a high degree of behavioral activation, and work output organisms frequently make effort-related decisions based upon cost/benefit analyses. Moreover, people with major depression other disorders show motivational symptoms such as anergia, psychomotor retardation, fatigue. It has been suggested that tasks measuring choice behavior could be used animal models the depression, present studies effects vesicular monoamine transport (VMAT) inhibitor...
Behavioral activation is a fundamental feature of motivation, and organisms frequently make effort-related decisions based upon evaluations reinforcement value response costs. Furthermore, people with major depression other disorders often show anergia, psychomotor retardation, fatigue, alterations in decision making. Tasks measuring effort-based making can be used as animal models the motivational symptoms depression, present studies characterized effects vesicular monoamine transport...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue
Brain dopamine, particularly in the nucleus accumbens, has been implicated activational aspects of motivation and effort-related processes. Accumbens dopamine depletions reduce tendency rats to work for food, alter decision making, but leave food such as appetite intact. Recent evidence indicates that purine neuromodulator adenosine, largely through actions on adenosine A2A receptors, also participates regulating Adenosine antagonists can reverse effects D2 choice, intra-accumbens injections...