A5005763187- Receptor Mechanisms and Signaling
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Parkinson's Disease Mechanisms and Treatments
- Ion channel regulation and function
- Neurological disorders and treatments
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Nicotinic Acetylcholine Receptors Study
- Treatment of Major Depression
- Tryptophan and brain disorders
- Curcumin's Biomedical Applications
- Genetic Neurodegenerative Diseases
- Attention Deficit Hyperactivity Disorder
- Neural and Behavioral Psychology Studies
- Eating Disorders and Behaviors
- Diet and metabolism studies
- Biochemical effects in animals
- Memory and Neural Mechanisms
- Mental Health Research Topics
- Behavioral and Psychological Studies
- Neuropeptides and Animal Physiology
- Pharmacological Receptor Mechanisms and Effects
Bristol-Myers Squibb (United States)
2024
University of Miami
2024
Bristol-Myers Squibb (Germany)
2024
Duke University
2024
University of Connecticut
2013-2021
Vanderbilt University
2017-2019
Vanderbilt University Medical Center
2019
John F. Kennedy Center for the Performing Arts
2018
University of North Carolina at Chapel Hill
2014
Universitat Jaume I
2014
Motivated behaviors are often characterized by a high degree of behavioral activation, and work output organisms frequently make effort-related decisions based upon cost/benefit analyses. Moreover, people with major depression other disorders show motivational symptoms such as anergia, psychomotor retardation, fatigue. It has been suggested that tasks measuring choice behavior could be used animal models the depression, present studies effects vesicular monoamine transport (VMAT) inhibitor...
Depression and related disorders are characterized by deficits in behavioral activation, exertion of effort, other psychomotor/motivational dysfunctions. Depressed patients show alterations effort-related decision making a bias towards selection low effort activities. It has been suggested that animal tests could be useful as models motivational dysfunctions seen psychopathology. Because clinical studies have inhibition catecholamine uptake may strategy for treatment symptoms, the present...
Behavioral activation is a fundamental feature of motivation, and organisms frequently make effort-related decisions based upon evaluations reinforcement value response costs. Furthermore, people with major depression other disorders often show anergia, psychomotor retardation, fatigue, alterations in decision making. Tasks measuring effort-based making can be used as animal models the motivational symptoms depression, present studies characterized effects vesicular monoamine transport...
We evaluated the processes controlling accumulation of collagen and elastin in main pulmonary arteries rats during an episode hypoxic hypertension. Explant cultures were incubated with [3H]proline to measure protein synthesis percent synthesis. Elastin was measured by [14C]valine incorporation into insoluble elastin. Relative increased twofold (from 1.1 +/- 0.2 x 10(3) 2.0 1.0 disintegrations per minute [14C]hydroxyproline/vessel/hr/mg protein), relative doubled 2% 4-5% total synthesis),...
Abstract Behavioral approaches utilizing rodents to study mood disorders have focused primarily on negative valence behaviors associated with potential threat (anxiety-related behaviors). However, for such as depression, positive that assess reward processing may be more translationally valid and predictive of antidepressant treatment outcome. Chronic corticosterone (CORT) administration is a well-validated pharmacological stressor increases avoidance in anxiety 1–4 . whether chronic stress...
Xanomeline and trospium chloride (formerly known as KarXT), a novel M