A5102760196- Diverse Educational Innovations Studies
- Child Development and Digital Technology
- Cerebral Palsy and Movement Disorders
- ATP Synthase and ATPases Research
- Metalloenzymes and iron-sulfur proteins
- Endoplasmic Reticulum Stress and Disease
- Hereditary Neurological Disorders
- Genetic Neurodegenerative Diseases
- Functional Brain Connectivity Studies
- Attention Deficit Hyperactivity Disorder
- Genomics and Rare Diseases
- Teacher Education and Leadership Studies
- Themes in Literature Analysis
- Religious Education and Schools
- Glycogen Storage Diseases and Myoclonus
- Metabolism and Genetic Disorders
- Mitochondrial Function and Pathology
- Neurological disorders and treatments
- Global Education and Multiculturalism
- Educator Training and Historical Pedagogy
- Genetics and Neurodevelopmental Disorders
University of Oxford
2015-2023
Internet Society
2023
Wellcome Centre for Mitochondrial Research
2015
Churchill Hospital
2015
Newcastle University
2010-2015
John Radcliffe Hospital
2015
Royal Hallamshire Hospital
2015
University of Sheffield
2015
Université d'Angers
2010
York Hospital
2010
Cerebral palsy is a sporadic disorder with multiple likely aetiologies, but frequently considered to be caused by birth asphyxia. Genetic investigations are rarely performed in patients cerebral and there little proven evidence of genetic causes. As part large project investigating children ataxia, we identified four our cohort diagnosis ataxic palsy. They were investigated using either targeted next generation sequencing or trio-based exome found have mutations three different genes, KCNC3,...
Late-onset ataxias are clinically and etiologically diverse. Patients rarely have defining clinical features, many remain classified as idiopathic, despite extensive clinical, metabolic, genetic investigations. Here we show that mutations in a gene known to cause hereditary spastic paraplegia ( SPG7 ) major of unexplained ataxia presenting mid-adult life.
The idea that the increased ubiquity of digital devices negatively impacts neurodevelopment is as compelling it disturbing. This study investigated this concern by systematically evaluating how different profiles screen-based engagement related to functional brain organization in late childhood. We studied participants from a large and representative sample young people participating first two years ABCD (ages 9-12 years) investigate relations between self-reported use various screen media...
Abstract View Supplementary Video 1 2 We report on a white Afrikaans family from eastern South Africa with three members affected North Sea progressive myoclonus epilepsy, resulting homozygous founder GOSR mutation (c.430G>T, p.Gly144Trp). The was identified by exomic sequencing in research study investigating childhood onset ataxias. All subjects presented ataxia, tremor, early gait difficulties, and myoclonic generalized tonic clonic ( GTC ) epilepsy. Each patient underwent deep brain...
OPA1 codes for a mitochondrial fusion protein found on the inner membrane. Mutations in are most common cause of autosomal dominant optic atrophy (DOA), and until recently, this was thought to be pure ocular disorder. By studying 104 patients from 45 independent families we have defined clinical spectrum new multisystem disease, which called DOA+. We show that extra-ocular neurological complications affect ∼20%, include sensorineural deafness childhood, followed by ataxia, myopathy,...
Themes, Theories, and Theraphy: The Teaching of Writing in College. Albert R. Kitzhaber. (New York: McGraw‐Hill, 1963. Pp. 175. $4.95.) Nongraded Elementary School, Revised Edition. John I. Goodlad Robert H. Anderson. Harcourt, Brace, World, 248. $1.95, paper.) Human Learning the School. P. DeCecco. Holt, Rinehart, Winston, 636. $4.75.) Health Instruction for Today's Schools. Dorothy Marguerite La Salle Gladys Greer. (Englewood Cliffs, New Jersey: Prentice‐Hall, 368. $6.75.) Lovejoy's Prep...
Education in Depressed Areas. Edited by A. Harry Passow. (New York: Bureau of Publications Teachers College, Columbia University, 1963. Pp.259. $4.75.) Educational Research: An Introduction. Walter R. Borg. David McKay Company, Pp. 418. $5.50.) Frontiers Education. Arthur E. Traxler. (Washington, D.C.: American Council on Education, 1962. 192. $2.50.) The Gifted Child, Year Book George Z. F. Bereday and Joseph Lauwerys. Harcourt, Brace, World, 541. $10.50.) Growth Development the Young...
Children's Literature: Strategies of Teaching. Robert Whitehead. Englewood Cliffs, New Jersey: Prentice‐Hall, 1968. 234 pp. Cloth, $5.95. Paper, $3.50. Freedom to Learn. Carl R. Rogers. Columbus, Ohio: Charles E. Merrill Publishing Company, 1969. 358 $6.95. Reading and Young Children. Verna Dieckman Anderson. York: The Macmillan 455 Reality Dream (Psychotherapy a Plains Indian). George Devereux. Preface by Margaret Mead. (Originally published International University Press. 1951). Garden...