Lei Yang

ORCID: 0009-0003-8377-6102
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Research Areas
  • CO2 Sequestration and Geologic Interactions
  • Flavonoids in Medical Research
  • Geothermal Energy Systems and Applications
  • Aluminum Alloys Composites Properties
  • Banking stability, regulation, efficiency
  • Medicinal plant effects and applications
  • Psoriasis: Treatment and Pathogenesis
  • Radar Systems and Signal Processing
  • Traditional Chinese Medicine Analysis
  • Heat transfer and supercritical fluids
  • Neurosurgical Procedures and Complications
  • Educational Technology and Assessment
  • Cellular and Composite Structures
  • Inflammatory Bowel Disease
  • Mast cells and histamine
  • Global Financial Crisis and Policies
  • Liver Disease Diagnosis and Treatment
  • Gut microbiota and health
  • Plant-derived Lignans Synthesis and Bioactivity
  • Underground infrastructure and sustainability
  • Advanced SAR Imaging Techniques
  • Spinal Fractures and Fixation Techniques
  • Air Quality and Health Impacts
  • Thermodynamic and Exergetic Analyses of Power and Cooling Systems
  • Evaluation Methods in Various Fields

Huashan Hospital
2022-2024

Fudan University
2012-2024

First Affiliated Hospital of Chengdu Medical College
2022

Chang'an University
2019-2022

University of Science and Technology of China
2017-2020

Beijing University of Chinese Medicine
2019

Qilu Hospital of Shandong University
2011-2018

Harbin Medical University
2016

Xinjiang University
2009

Abstract Background Generalized Additive Model (GAM) provides a flexible and effective technique for modelling nonlinear time-series in studies of the health effects environmental factors. However, GAM assumes that errors are mutually independent, while time series can be correlated adjacent points. Here, with Autoregressive terms (GAMAR) is introduced to fill this gap. Methods Parameters GAMAR estimated by maximum partial likelihood using modified Newton’s method, difference between...

10.1186/1471-2288-12-165 article EN cc-by BMC Medical Research Methodology 2012-10-30

The purpose of this study was to report on a series 162 patients presenting with juvenile nasopharyngeal angiofibroma in single academic hospital during the past 17 years, an effort compare outcomes between open and transnasal endoscopic approach, define ideal treatment strategy.Patients who received either or surgery minimum follow-up 6 months were selected. Local control complications compared groups.Retrospectively, clinical data, surgical reports, pre- postoperative images, information...

10.1002/lary.24522 article EN The Laryngoscope 2013-11-13

Summary Primary immune thrombocytopenia (ITP) is an immune‐mediated disorder in which disturbed cytokine profiles have been found. Interleukin‐27 (IL27) has shown to bear both proinflammatory and anti‐inflammtory effects. In the present study, plasma levels of IL27, interferon gamma (IFNG), IL4, IL17A were determined by enzyme‐linked immunosorbent assay 23 active ITP patients, 20 patients remission healthy controls. mRNA expression IL27 , EBI3 receptor ( IL27RA ), RAR‐related orphan C RORC )...

10.1111/j.1365-2141.2011.08614.x article EN British Journal of Haematology 2011-03-08

This study employed a dynamic conditional correlation–mixed-data sampling (DCC–MIDAS) approach and panel data analysis to examine the factors that influence long-term correlation between crude oil stock markets. Our shows there is positive prices markets, except during 2008 global financial crisis 2011 European debt crisis. We also found macroeconomic have significant impact on this correlation. Specifically, risk-free rate has effect, whereas economic activity credit risk negative effect....

10.3390/en12214123 article EN cc-by Energies 2019-10-29

Ulcerative colitis is one of the main gastrointestinal diseases that threaten human health. This study investigated effect Limosilactobacillus fermentum HFY06 (LF-HFY06) on dextran sulfate sodium (DSS)-induced murine colitis. The protective LF-HFY06 was evaluated by examining length and histopathological sections colon, related biochemical indicators, genes to inflammation. Direct microscopic observations showed increased colon ameliorated pathological damage induced DSS. indicators enhanced...

10.3389/fmicb.2022.935792 article EN cc-by Frontiers in Microbiology 2022-09-12

Adverse drug reactions (ADRs) are responsible for failure in clinical trials and affect life quality of patients. The identification ADRs during the early phases development is an important task. Therefore, predicting potential protein targets eliciting essential understanding pathogenesis ADRs. In this study, we proposed a computational algorithm,Integrated Network Protein-ADR relations (INPADR), to infer protein-ADR based on integrated network. First, network was constructed by connecting...

10.1038/srep36325 article EN cc-by Scientific Reports 2016-11-02

Cordyceps sinensis is a traditional Chinese herbal medicine that has been used for centuries in Asia as tonic to soothe the lung treatment of respiratory diseases. The aim present study was determine effects C. on airway remodeling chronic obstructive pulmonary disease (COPD) and investigate underlying molecular mechanisms. Rats with COPD were orally administered at low, moderate or high doses (2.5, 5 7.5 g/kg/day, respectively) 12 weeks. Airway tissue histopathology, inflammation evaluated....

10.3892/etm.2018.5777 article EN Experimental and Therapeutic Medicine 2018-01-19

Psoriasis is a chronic proliferative skin disorder characterised by abnormal epidermal differentiation. The Fuzhenghefuzhiyang (FZHFZY) formula created Chuanjian Lu, master of Chinese medicine in dermatology, has been external used the Guangdong Provincial Hospital Medicine for treatment psoriasis, but its mechanisms action against psoriasis remain poorly understood. This study involved an exploration effects FZHFZY on differentiation and underlying interleukin (IL)-17A/IL-22/interferon...

10.3389/fphar.2021.650816 article EN cc-by Frontiers in Pharmacology 2021-08-11

Radar has been increasingly used in indoor applications. This paper introduces an tracking system that uses a 24-GHz FMCW radar. Several methods are exploited to alleviate the problem of insufficient resolution caused by low bandwidth. To further distinguish stationary targets, method based on moving target indicator is proposed. The results show these effective and two quasi-static targets can be successfully distinguished.

10.1109/iws55252.2022.9977822 article EN 2018 IEEE MTT-S International Wireless Symposium (IWS) 2022-08-12

In view of the phenomenon guarantee network formed by mutual Chinese enterprises. First, mechanism crisis formation in regional circles is analysed through contagion effect, then enterprise and model are constructed using agent method. Second, evolution rules a circle under different situations designed. Finally, with help Anylogic simulation software, dynamic process "brewing-triggering-burst-diffusion" realised. By simulating contrast demonstration operation effect situations, we find...

10.1080/17477778.2020.1750314 article EN Journal of Simulation 2020-04-19

The aim of this study was to describe the clinical and procedural risk factors associated with unplanned neurosurgical intensive care unit (NICU) readmission patients after elective supratentorial brain tumor resection serves as an exploratory analysis toward development a stratification tool that may be prospectively applied patient population.

10.3171/2022.10.jns221318 article EN Journal of neurosurgery 2022-12-23

Ethnopharmacological relevance: Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF), a classical traditional Chinese herbal consisting of five herbs, is used clinically in China to treat inflammatory lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and idiopathic fibrosis (IPF). Its mechanism for treating asthma COPD has been reported, however, how it works against IPF remains unclear.Research purpose: Our study aims observe the therapeutic effect JWBSYQF on further identify...

10.2139/ssrn.4356722 article EN 2023-01-01

Expressway projects have a significant investment, long construction period, and many influencing factors. It is necessary to explore the theory practice of modernization expressway management improve their level further. Based on systematically summarizing development process focus highway modernization, this paper clarifies concepts core essentials for simplifies it as concept "intelligentization, construction, quality". The analyzes connotation from elements, three-dimensional structure,...

10.1061/jhtrcq.0000851 article EN Journal of Highway and Transportation Research and Development (English Edition) 2022-12-01
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