A5101409732- Advanced Fiber Optic Sensors
- Soil Carbon and Nitrogen Dynamics
- Advanced Fiber Laser Technologies
- Photonic and Optical Devices
- Viral gastroenteritis research and epidemiology
- Soil and Water Nutrient Dynamics
- Animal Virus Infections Studies
- Photonic Crystal and Fiber Optics
- Asthma and respiratory diseases
- Advanced Glycation End Products research
- RNA modifications and cancer
- Advanced Photonic Communication Systems
- MicroRNA in disease regulation
- Optical Network Technologies
- Cancer-related molecular mechanisms research
- Estrogen and related hormone effects
- Viral Infections and Vectors
- Advanced biosensing and bioanalysis techniques
- Plant Virus Research Studies
- Circular RNAs in diseases
- Plant Micronutrient Interactions and Effects
- Virus-based gene therapy research
- Plant nutrient uptake and metabolism
- Pharmacological Effects of Natural Compounds
- Clay minerals and soil interactions
Sichuan University
2007-2025
Chinese Academy of Sciences
2014-2025
West China Second University Hospital of Sichuan University
2024-2025
Institute of Botany
2020-2025
University of Chinese Academy of Sciences
2015-2025
Academy of Military Medical Sciences
2024-2025
Huashan Hospital
2021-2025
Universitätsklinikum Würzburg
2024-2025
Qingdao Center of Resource Chemistry and New Materials
2019-2025
Fudan University
2021-2024
Cervical cancer has been shown to be one of the leading cancer-related death causes all over world. Several studies demonstrates that hsa_circ_0023404 plays a crucial role in progression cervical cancer; however, detailed mechanism regulating metastasis and chemoresistance remains unclear.We used RT-qPCR westernblot approach detect expression levels various genes tumors cells. To examine invasion lymphatic vessel formation Human Dermal Lymphatic Endothelial Cells (HDLEC), transwell assay...
Cervical cancer has been one of the most common in women worldwide. However, detailed mechanism underlying circMTO1-regulated cervical remains unclear.RT-qPCR and westernblot were used to examine genes expression levels. Wound healing assay transwell invasion utilized probe migration abilities cells. In addition, cell viability apoptosis measured by MTT TUNEL assay, respectively. Finally, we employed bioinformatic approach analyze gene levels clinical tissues.circMTO1 was shown be greatly...
Abstract Tumor progression requires the communication between tumor cells and microenvironment (TME). Cancer-associated fibroblasts (CAFs) are major components of stromal cells. CAFs contribute to metastasis process through direct or indirect interaction with cells; however, underlying mechanism is largely unknown. Here, we reported that autophagy was upregulated in lung cancer-associated compared normal (NFs), responsible for promoting effect on non-small cell cancer (NSCLC) migration...
Sodium-glucose transport protein 2 inhibitors (SGLT2i) slow the progression of renal dysfunction and improve prognosis patients with heart failure. Amyloidosis constitutes an important subgroup for which evidence is lacking. Amyloidotic fibrils originating from misfolded transthyretin light chains are causal agents in ATTR AL amyloidosis. In these most frequent subtypes, cardiac involvement common organ manifestation. Because function frequently deteriorate over time, even under best...
Axon development plays a pivotal role in the formation of synapse, nodes Ranvier, and myelin sheath. Interleukin-1β (IL-1β) produced by microglia may cause myelination disturbances through suppression oligodendrocyte progenitor cell maturation septic neonatal rats. Here, we explored if microglia-derived IL-1β would disturb axon corpus callosum (CC) following lipopolysaccharide (LPS) administration, so, whether it is associated with disorder synapse cerebral cortex node Ranvier....
The demand for distributed acoustic sensors, which are capable of reconstructing the amplitude, frequency, and phase an field, is increasing. These sensors typically realized by phase-sensitive optical time-domain reflectometry (Φ-OTDR). However, common Φ-OTDR systems suffer from a fading phenomenon, causes amplitude fluctuation on Rayleigh backscattering traces, scattered light may not have enough intensity in some regions. areas low that be even lower than system noise floor during periods...
Neuroinflammation elicited by microglia plays a key role in periventricular white matter (PWM) damage (PWMD) induced infectious exposure. This study aimed to determine if microglia‐derived interleukin‐1β (IL‐1β) would induce hypomyelination through suppression of maturation oligodendrocyte progenitor cells (OPCs) the developing PWM. Sprague‐Dawley rats (1‐day old) were injected with lipopolysaccharide (LPS) (1 mg/kg) intraperitoneally, following which upregulated expression IL‐1β and IL‐1...
Mediator of IRF3 activation (MITA, also named as STING/ERIS/MPYS/TMEM173), is essential to DNA virus- or cytosolic DNA-triggered innate immune responses. In this study, we demonstrated the negative regulatory role RING-finger protein (RNF) 90 in responses targeting MITA. RNF90 promoted K48-linked ubiquitination MITA and its proteasome-dependent degradation. Overexpression inhibited HSV-1- DNA-induced whereas knockdown had opposite effects. Moreover, RNF90-deficient bone marrow-derived...
The performance of distributed optical fiber acoustic sensor as a function parameters such the linewidth laser, probe pulse width, and amplitude frequency perturbation is experimentally studied. aim this study to confirm outcome simulation results obtained previously. It shown that experimental are in good agreement, precision sensing system depends on width pulse, well perturbation. can be enhanced by reducing while increasing laser.
Abstract Nutrient limitation and metal toxicity have been implicated in changes of grassland communities by nitrogen (N) deposition. Below‐ground processes, especially those at the soil–root interface, play important roles determining variation nutrient concentrations plants. However, few studies specifically focused on these processes mineral‐element acquisition plants response to N enrichment. Here we investigated contributions below‐ground interface differential phosphorus (P), calcium...
Cancer progression depends on the communication between tumor cells and microenvironment. Cancer-associated fibroblasts (CAFs) are a major component of stromal cells. CAFs promote cancer metastasis; however, it has not been evaluated whether N6-methyladenosine (m6A) modification is responsible for CAFs' role in metastasis. In present study, we found that promoted migration invasion non-small cell lung (NSCLC) by elevating m6A NSCLC Methyltransferase-like 3 (METTL3) mediated effect...