- Protein Tyrosine Phosphatases
- Cytokine Signaling Pathways and Interactions
- PI3K/AKT/mTOR signaling in cancer
- S100 Proteins and Annexins
- Melanoma and MAPK Pathways
- Liver physiology and pathology
- Liver Disease Diagnosis and Treatment
- 14-3-3 protein interactions
- Liver Disease and Transplantation
- Immune Response and Inflammation
- MicroRNA in disease regulation
- Neuroinflammation and Neurodegeneration Mechanisms
Bengbu Medical College
2024
The University of Queensland
1993
University of Southern California
1993
Medical Council of Canada
1993
University of British Columbia
1993
A putative mitogen-activated protein kinase (MAPK) has recently been identified, which potentially phosphorylates the human epidermal growth factor (EGF) receptor at a physiological site (Thr-669) and is distinguished from other MAPKdextracellular signal-regulated kinases (ERKs) on basis of chromatographic, immunological, kinetic data.Here we report that this newly discovered MAPK physically associated with EGF in A431 cells related receptor/tyrosine HEW (encoded by c-neu) enzyme...
Septic encephalopathy (SE) represents a severe inflammatory syndrome linked to elevated septic mortality rates, lacking specific therapeutic interventions, and often resulting in enduring neurological sequelae. The present investigation endeavors elucidate the involvement of C-X-C Motif Chemokine Receptor 2 (CXCR2) pathogenesis SE explore potential CXCR2 modulation as avenue for SE. Employing murine model induced by lipopolysaccharide (LPS) administration, knockout mice inhibitor SB225002...