Fengjiao Wu

ORCID: 0009-0003-8539-8686
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About
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Research Areas
  • Protein Tyrosine Phosphatases
  • Cytokine Signaling Pathways and Interactions
  • PI3K/AKT/mTOR signaling in cancer
  • S100 Proteins and Annexins
  • Melanoma and MAPK Pathways
  • Liver physiology and pathology
  • Liver Disease Diagnosis and Treatment
  • 14-3-3 protein interactions
  • Liver Disease and Transplantation
  • Immune Response and Inflammation
  • MicroRNA in disease regulation
  • Neuroinflammation and Neurodegeneration Mechanisms

Bengbu Medical College
2024

The University of Queensland
1993

University of Southern California
1993

Medical Council of Canada
1993

University of British Columbia
1993

A putative mitogen-activated protein kinase (MAPK) has recently been identified, which potentially phosphorylates the human epidermal growth factor (EGF) receptor at a physiological site (Thr-669) and is distinguished from other MAPKdextracellular signal-regulated kinases (ERKs) on basis of chromatographic, immunological, kinetic data.Here we report that this newly discovered MAPK physically associated with EGF in A431 cells related receptor/tyrosine HEW (encoded by c-neu) enzyme...

10.1016/s0021-9258(17)46832-3 article EN cc-by Journal of Biological Chemistry 1993-08-01

Septic encephalopathy (SE) represents a severe inflammatory syndrome linked to elevated septic mortality rates, lacking specific therapeutic interventions, and often resulting in enduring neurological sequelae. The present investigation endeavors elucidate the involvement of C-X-C Motif Chemokine Receptor 2 (CXCR2) pathogenesis SE explore potential CXCR2 modulation as avenue for SE. Employing murine model induced by lipopolysaccharide (LPS) administration, knockout mice inhibitor SB225002...

10.3390/biomedicines12071536 article EN cc-by Biomedicines 2024-07-11
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