A5093127123- Crystallization and Solubility Studies
- Supramolecular Chemistry and Complexes
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Organic Chemistry Cycloaddition Reactions
- Crystal structures of chemical compounds
- Drug Solubulity and Delivery Systems
- Mass Spectrometry Techniques and Applications
- Advanced NMR Techniques and Applications
- Eicosanoids and Hypertension Pharmacology
Tomas Bata University in Zlín
2010-2023
Novel binding motifs suitable for the construction of multitopic guest-based molecular devices (e.g., switches, sensors, data storage, and catalysts) are needed in supramolecular chemistry. No rigid, aliphatic motif that allows axial disubstitution has been described cucurbit[6]uril (CB6) so far. We prepared three model guests combining spiro[3.3]heptane bicyclo[1.1.1]pentane centerpieces with imidazolium ammonium termini. their properties toward CB6/7 α-/β-CD using NMR, titration...
In the title compound, C18H24, adamantane cage consists of three fused cyclohexane rings in almost ideal chair conformations, with C—C—C angles range 108.0 (14)–111.1 (15)°. The phenyl and 1-adamantyl substituents adopt anti orientations a C—C—C—C torsion angle 177.10 (16)°. crystal packing, molecules are linked by weak C—H⋯π interactions into chains along axis.
Rationale Bisimidazolium salts (BIMs) represent an interesting family of ditopic ligands that are used in the construction supramolecular systems with hosts based on cyclodextrins or cucurbit[n]urils. Understanding fragmentation mechanism individual BIMs and how this changes after complexation cucurbit[n]urils can bring new insight into intrinsic host‐guest relationship, thereby allowing utilization mass spectrometry to describe binding behavior. Methods Selectively 2 H‐labeled...