A5103268406- Flavonoids in Medical Research
- Saffron Plant Research Studies
- Genetics, Aging, and Longevity in Model Organisms
- Curcumin's Biomedical Applications
- GDF15 and Related Biomarkers
- Ubiquitin and proteasome pathways
- 14-3-3 protein interactions
- Microbial Natural Products and Biosynthesis
- Synthesis and biological activity
- FOXO transcription factor regulation
- Cancer Mechanisms and Therapy
- Heavy Metal Exposure and Toxicity
- Genetic and phenotypic traits in livestock
Union Hospital
2018-2023
Jilin University
2018-2019
Henan Cancer Hospital
2015
Zhengzhou University
2015
Oxidative stress (OS) is one of the responsible factors for causing renal diseases. For treatment or prevention disease, antioxidants use could be a hopeful therapeutic mediation as they block oxidative reaction along with inflammatory process. Wogonin (Wog) plant flavonoid, pharmacologically active component Scutellaria baicalensis Georgi (Huang Qui), which exhibits antioxidant activity. In this investigation, we explored nephroprotective activity Wog on cadmium (Cd)-induced nephron...
Forkhead Box M1 (FOXM1) is an oncogenic transcription factor implicated in breast cancer progression and metastasis. However, the clinical significance of FOXM1 its associated signaling genes human still needed to be clarified. In this study, we first analyzed co-expression gene pattern three expression microarray datasets from Oncomine database. Cell division cycle 8 (CDCA8) was identified correlate closely with FOXM1. silico analysis further indicated that CDCA8 overexpressed tissues...
YWHAZ (14-3-3ζ) has been reported to be a prognostic marker for various tumors and play crucial role in many oncogenic processes, including proliferation, migration invasion.However, the functional mechanism of gastric cancer (GC) are not detailed still require study.Herein, endogenous expression cell line BGC-823 was silenced by YWHAZ-specific short hairpin RNA (shRNA).Our data showed that silencing resulted cycle arrest cells.Further, YWHAZ-silenced cells acquired increased apoptosis rate,...
Background: Gastric cancer stands as a primary cause of cancer-related deaths worldwide, making the discovery new therapeutic agents essential for enhancing treatment outcomes. Curcumin, polyphenolic compound found in turmeric (Curcuma longa), has demonstrated potential multiple types due to its anti-cancer characteristics. This research aimed examine impact curcumin on gastric cell growth, migration, and invasion, well influence phosphoinositide 3-kinase (PI3K) signaling cascade. Methods:...