Paolo Costa

ORCID: 0009-0004-1145-5120
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About
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Research Areas
  • Biofuel production and bioconversion
  • biodegradable polymer synthesis and properties
  • Microplastics and Plastic Pollution
  • Nanoplatforms for cancer theranostics
  • Anesthesia and Neurotoxicity Research
  • Cardiac Valve Diseases and Treatments
  • Microbial Metabolic Engineering and Bioproduction
  • Cardiac Ischemia and Reperfusion
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Anaerobic Digestion and Biogas Production
  • Mechanical Circulatory Support Devices
  • Cardiac and Coronary Surgery Techniques
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Minerals Flotation and Separation Techniques
  • Electrolyte and hormonal disorders
  • Immune Cell Function and Interaction
  • Macrophage Migration Inhibitory Factor
  • Hearing Loss and Rehabilitation
  • IL-33, ST2, and ILC Pathways
  • Water Systems and Optimization
  • Receptor Mechanisms and Signaling
  • Dermatologic Treatments and Research
  • Additive Manufacturing and 3D Printing Technologies
  • Field-Flow Fractionation Techniques
  • Powder Metallurgy Techniques and Materials

University of Padua
2022-2024

Universidade da Coruña
2023

Jewish General Hospital
2022

University of Turin
1973-2021

Ospedale Maggiore
1989

University of Genoa
1976

In the challenge of mitigating greenhouse gases produced mainly by fossil fuels, recovery agricultural and food waste to produce biohydrogen dark fermentation is considered a promising source for future. However, industrial-scale production remains challenging several parameters significantly influencing application technology need be finely tuned. present study, an evaluation from cassava pineapple waste, widely available in many African countries, was carried out using different microbial...

10.1016/j.ijhydene.2023.07.348 article EN cc-by-nc-nd International Journal of Hydrogen Energy 2023-08-16

We investigated the role of NFE2L3 transcription factor in inflammation-induced colorectal cancer. Our studies revealed that Nfe2l3-/- mice exhibit significantly less inflammation colon, reduced tumor size and numbers, skewed localization tumors with a more pronounced decrease distal colon. CIBERSORT analysis RNA-seq data from normal tissue predicted reduction mast cells animals, which was confirmed by toluidine blue staining. Concomitantly, transcript levels Il33 Rab27a, both important...

10.1038/s41388-022-02192-2 article EN cc-by Oncogene 2022-01-28

Traditional plastics represent a tremendous threat to the environment because of increases in polluting manufacturing as well their very extended degradation time. Polyhydroxyalkanoates (PHAs) are polymers with similar performance plastic but compostable and synthesizable from renewable sources therefore could be replacement for fossil-based plastics. However, production costs still too high, thus demanding investigation new cheap substrates. In this sense, agricultural wastes attractive...

10.3390/polym14245529 article EN Polymers 2022-12-16

A study of brainstem auditory evoked potentials (BAEPs) and pattern reversal visual (VEPs), recorded in intercritical phase, was carried out 20 subjects (10 suffering from common migraine 10 vertebrobasilar TIA) order to obtain a comparative evaluation cortical-subcortical functions. The data we obtained demonstrate the presence BAEPs alterations patients with previous TIA: no abnormalities were found group. VEPs parameters are normal both groups. Our show that so-called “stimulus-related”...

10.1177/03331024850050s209 article EN Cephalalgia 1985-05-01

The environmental concerns regarding fossil plastics call for alternative biopolymers such as polyhydroxyalkanoates (PHAs) whose manufacturing costs are however still too elevated. Autotrophic microbes like Cupriavidus necator, able to convert CO2 and H2 into PHAs, offer an additional strategy. Typically, the preferred source expensive pure gases or syngas, which has toxic compounds most PHAs-accumulating strains. In this work, first time, originating from acidogenic reactor were converted...

10.1016/j.biortech.2023.129880 article EN cc-by Bioresource Technology 2023-10-16

10.1023/a:1004303325978 article EN Journal of Materials Science 1998-01-01

Combination of butanol-hyperproducing and hypertolerant phenotypes is essential for developing microbial strains suitable industrial production bio-butanol, one the most promising liquid biofuels. Clostridium cellulovorans among with highest potential direct n -butanol from lignocellulosic wastes, a process that would significantly reduce cost bio-butanol. However, butanol exhibits higher toxicity compared to ethanol C. tolerance this solvent low. In present investigation, comparative...

10.3389/fmicb.2021.674639 article EN cc-by Frontiers in Microbiology 2021-07-21

Neutrophil oxidative metabolism, C3d and beta 2 microglobulin levels, were assessed in nine consecutive patients undergoing cardiopulmonary bypass surgery with polypropylene hollow fiber oxygenators for open cardiac operations. Generation of oxygen free radicals by neutrophils was measured as luminol-enhanced chemiluminescence after stimulation opsonized Zymosan phorbol myristate acetate. A significant increase light emission detected using both the stimulators. Moreover, a remarkable levels...

10.1111/j.1525-1594.1990.tb01594.x article EN Artificial Organs 1990-02-01

Magnesium is frequently added to Cu powder in the atomisation process obtain a higher particle surface. Mg tends oxidise very easily leading formation of MgO on particles. This phenomenon increases with temperature. Unfortunately presence this surface oxide hinders sintering process. Three different powders were produced three amounts. These used production 90/10 elemental bronzes. The behaviour bronzes was studied by means dilatometry and DSC. Partial at temperatures lower than temperature...

10.1179/003258905x37765 article EN Powder Metallurgy 2005-06-01

10.1016/0009-2509(76)80040-1 article EN Chemical Engineering Science 1976-01-01

Neutrophil oxidative metabolism was prospectively assessed in 9 consecutive patients undergoing cardiopulmonary bypass (CPB) with polypropylene hollow fiber oxygenators for open cardiac operations. Blood samples were collected at 10, 20, and 30 min of CPB. The generation oxygen-free radicals by neutrophils measured as Iuminol-enhanced chemiluminescence after stimulation opsonized Zymosan Phorbol Myristate Acetate. A significant increase light emission detected using both the stimulators....

10.1097/00002480-198907000-00063 article EN ASAIO Transactions 1989-07-01

Water distribution system management involves complex problems and needs reliable models of the water supply system. The rising complexity systems to be managed today has exceeded a certain threshold, beyond which it necessary change scientific paradigm that supports these systems. On other hand, is clear type information required not, generically speaking, quantitative. For instance, proper functioning node guaranteed as long pressure falls within range, does not require precise value for...

10.1061/40430(1999)67 article EN 1999-06-03
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