- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Lipoproteins and Cardiovascular Health
- Infective Endocarditis Diagnosis and Management
- Meta-analysis and systematic reviews
- Acute Ischemic Stroke Management
- Academic Writing and Publishing
- Cardiac Arrhythmias and Treatments
- Medication Adherence and Compliance
- Atherosclerosis and Cardiovascular Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Sympathectomy and Hyperhidrosis Treatments
- Mobile Health and mHealth Applications
- Computational Drug Discovery Methods
- Vascular Procedures and Complications
- Health Literacy and Information Accessibility
- Acute Kidney Injury Research
- Coronary Artery Anomalies
- Cardiac tumors and thrombi
- Peripheral Artery Disease Management
University of Catania
2020-2024
Policlinico Universitario di Catania
2020-2024
Università degli Studi di Enna Kore
2024
Ospedali Riuniti Umberto I
2024
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2020
The evolution of anticoagulation therapy, from vitamin K antagonists to the advent direct oral anticoagulants (DOACs) almost two decades ago, marks significant progress. Despite improved safety demonstrated in pivotal trials and post-marketing observations, persistent concerns exist, particularly regarding bleeding risk absence therapeutic indications specific subgroups or clinical contexts. Factor XI (FXI) has recently emerged as a contributor intraluminal thrombus formation growth, playing...
Noninferiority trials are increasingly common in cardiovascular medicine, but their reporting and interpretation challenging, particularly when an absolute risk difference is used as noninferiority margin.
Single antiplatelet therapy (SAPT) and intensified antithrombotic regimens (prolonged dual [DAPT] or pathway inhibition [DPI]) are recommended for secondary prevention in patients who underwent percutaneous coronary intervention (PCI) after initial DAPT. We aimed to characterize eligibility such strategies explore what extent guidelines applied clinical practice. Patients PCI acute chronic syndrome completed DAPT were analyzed from a prospective registry. categorized into SAPT, prolonged...
Atherosclerosis is the most frequent cause of coronary artery disease (CAD) and inflammation a key driver its pathogenesis. Targeting represents novel therapeutic option beyond management conventional cardiovascular risk factors. Recent efforts in research were aimed at investigating efficacy safety existing anti-inflammatory drugs.The multimodal activation immune response enables several approaches to mitigate inflammatory burden atherosclerosis, which include general preventive measures...
Background: According to the actual guidelines regarding severe aortic valve stenosis (AS), symptoms are most important trigger for replacement (AVR). However, objective analysis of cardiological clinic can be confused, considering aging population this disease affects and comorbidities. Objectives: Looking an marker disease, useful scheduling correct AVR, we researched relation between some biochemical markers left ventricular (LV) dysfunction its global longitudinal strain. Materials...
Randomized trials are often presented at medical conferences and published simultaneously or later. Predictors of simultaneous publication its consequences undetermined. Our aim was to characterize the practice publication, identify predictors, evaluate impact.
Introduction and objectives: Randomized trials are often presented at medical conferences published simultaneously or later. Predictors of simultaneous publication its consequences undetermined. Our aim was to characterize the practice publication, identify predictors, evaluate impact. Methods: In this cross-sectional study, we included randomized late-breaking science sessions major cardiovascular from 2015 2021. The association trial characteristics with timing analyzed. impact vs...