A5088946095- Blood Pressure and Hypertension Studies
- Frailty in Older Adults
- Nutrition and Health in Aging
- Cardiovascular Syncope and Autonomic Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Heart Rate Variability and Autonomic Control
- Hemodynamic Monitoring and Therapy
- Pharmaceutical Practices and Patient Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Nutritional Studies and Diet
- Pharmacology and Obesity Treatment
- Treatment of Major Depression
Azienda Ospedaliero-Universitaria Careggi
2020-2025
University of Florence
2020-2025
In older adults, trazodone is frequently prescribed for anxiety and insomnia owing to its perceived greater tolerability in comparison with benzodiazepines. However, it may have hypotensive effects. The aim of this study investigate the effects on orthostatic blood pressure (BP) response risk syncope falls hypertensive adults. A longitudinal observational involving patients ≥ 75 years was conducted two geriatric outpatient clinics Florence, Italy. At baseline, participants underwent a 3-min...
To date, few studies have investigated frailty in hypertensive individuals. This study aimed at identifying the prevalence of a sample older outpatients using six different identification tools. Clinical correlates and agreement between definitions were also investigated.
Despite high prevalence of hypertension, few studies have analysed the adverse effects (AEs) antihypertensive medications, especially in older patients.
Objective: Resistant Hypertension is not uncommon in clinical practice. The causal role of medical therapy often underestimated. Design and method: We describe a case (pseudo)Resistant where medications contributed to (pseudo)resistance. Results: An 83-year-old male patient was referred our Clinic July 2020 for poor blood pressure (BP) control despite polytherapy (Valsartan 320 mg/die, Nebivolol 5 Doxazosin 4 Clonidine patch Lercanidipine 20 mg). Medical history included recent stroke (June...
Objective: Trazodone is commonly prescribed in older adults and may have hypotensive effects due to the inhibition of alpha-adrenergic receptors. The present study aimed investigate trazodone on blood pressure (BP) its related risk syncope falls hypertensive adults. Design method: A longitudinal observational involving patients aged 75 or was conducted at Hypertension Clinic Memory Division Geriatric Intensive Care Medicine, Careggi Hospital, Florence. Participants underwent multidimensional...
Objective: Older adults have increased susceptibility to hypotension. Hypotensive episodes a negative prognostic impact at old age, being associated with adverse events such as syncope, falls and injuries, which impair quality of life functional autonomy. 24-hour ambulatory blood pressure monitoring (ABPM) is useful diagnostic tool detect hypotension, although it rarely used for this purpose. The present study aimed assessing the prevalence clinical variables hypotensive on ABPM among older...
Objective: The SPRINT trial demonstrated the benefits of intensive blood pressure (BP) control in older hypertensive adults, including frailer patients. However, how those results can be applied geriatric population remains doubtful, due to highly selective inclusion criteria and low levels clinical frailty aforementioned series. This study aimed assess applicability a real world sample adults analysed association between BP functional decline by eligibility. Design method: We exclusion...
Objective: To date, few studies have evaluated frailty in older adults with hypertension and the most appropriate tool to quantify this population has yet be identified. The present study aimed investigate prognostic impact of on decline functional autonomy a sample hypertensive adults. Design method: We performed longitudinal observational including patients aged 75 or at Hypertension Clinic Memory Division Geriatric Intensive Care Medicine, Careggi Hospital, Florence. Participants...
To assess the prevalence of frailty among hypertensive older adults according to most widely used measure tools and investigate clinical correlates frailty.A prospective observational study was conducted involving consecutive patients aged 75 or referred a Hypertension clinic Memory in Florence, Italy. The following were applied: Fried Frailty Phenotype (FFP), Index, Clinical Scale (CFS), Postal Score (FPS), Short Physical Performance Battery (SPPB), gait velocity. Cohen's kappa coefficient...
Objective: In nursing home (NH) residents, hypotension may predispose to adverse events including falls, fractures and mortality. Yet, evidence on detected by ambulatory blood pressure monitoring (ABPM) is scarce in this setting. This study aimed determine the prevalence clinical predictors of NH residents analyze its related ABPM profile. Design method: We retrospectively analysed data from a sample 100 undergoing comprehensive geriatric assessment ABPM. Ambulatory was defined as systolic...