K. R. Quinn
ORCID:
0009-0004-2766-3303
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About
Contact & Profiles
A5080037744
Research Areas
- Occupational and environmental lung diseases
- Acute Myeloid Leukemia Research
- RNA modifications and cancer
- Biomedical and Engineering Education
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Protein Tyrosine Phosphatases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Acute Lymphoblastic Leukemia research
University of Cincinnati
2024
Andrew Stiff
Maarten Fornerod
Bailee Kain
Deedra Nicolet
Benjamin Kelly
and 59
more
Katherine Miller
Krzysztof Mrózek
Isaiah Boateng
Audrey Bollas
Elizabeth A.R. Garfinkle
O. M. Momoh
F A Fasola
H.O. Olawumi
Nuria Mencia-Trinchant
Jean F. Kloppers
Anne‐Cecilia van Marle
Eileen Hu
Saranga Wijeratne
Gregory Wheeler
Christopher J. Walker
Jill Buss
Adrienne Heyrosa
Helee Desai
Andrea Laganson
Ethan Hamp
Yazan Abu-Shihab
Hasan Abaza
Parker Kronen
Sidharth Sen
Megan Johnstone
K. R. Quinn
Ben Wronowski
Erin Hertlein
Linde A. Miles
Alice S. Mims
Christopher C. Oakes
James S. Blachly
Karilyn Larkin
Bethany L. Mundy-Bosse
Andrew J. Carroll
Bayard L. Powell
Jonathan E. Kolitz
Richard M. Stone
Cassandra Duarte
Diana Abbott
Maria L. Amaya
Craig T. Jordan
Geoffrey L. Uy
Wendy Stock
Kellie J. Archer
Electra D. Paskett
Monica L. Guzman
Ross L. Levine
Kamal Menghrajani
Debyani Chakravarty
Michael F. Berger
Daniel Bottomly
Shannon K. McWeeney
Jeffrey W. Tyner
John C. Byrd
Nathan Salomonis
H. Leighton Grimes
Elaine R. Mardis
Ann‐Kathrin Eisfeld
10.1038/s41588-024-01929-x
article
EN
cc-by-nc-nd
Nature Genetics
2024-10-04
Sydney Fobare
Chia Sharpe
K. R. Quinn
K. Dawn Bryant
Linde A. Miles
and 24
more
Robert L. Bowman
Carolyn Cheney
Casie Furby
Marissa Long
Kaytlynn Fyock
Ben Wronowski
James R. Lerma
Allison Mullaney
Krzysztof Mrózek
Deedra Nicolet
Tom Sesterhenn
Megan Johnstone
N. Shesh
Chandrashekhar Pasare
Nives Zimmermann
Andrew J. Carroll
Richard M. Stone
Eunice S. Wang
Jonathan E. Kolitz
Bayard L. Powell
John P. Perentesis
Ann‐Kathrin Eisfeld
Erin Hertlein
John C. Byrd
Summary Mutations in protein tyrosine phosphatase non-receptor type 11 ( PTPN11 ) have been considered late acquired mutations acute myeloid leukemia (AML) development. To interrogate the ontogeny of mutations, we utilized single-cell DNA sequencing and identified that can occur as initiating events some AML patients when accompanied by strong oncogenic drivers, commonly NPM1 mutations. The co-driver role was confirmed a novel murine model exhibits an phenotype with early expansion diverse...
10.1101/2024.09.18.612239
preprint
EN
bioRxiv (Cold Spring Harbor Laboratory)
2024-09-20
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