Catherine E. Lyons

ORCID: 0009-0004-3202-9294
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About
Contact & Profiles
Research Areas
  • Immunotherapy and Immune Responses
  • Eosinophilic Esophagitis
  • Animal Genetics and Reproduction
  • Computational Drug Discovery Methods
  • Dermatology and Skin Diseases
  • Immunodeficiency and Autoimmune Disorders
  • Mast cells and histamine
  • Antifungal resistance and susceptibility
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Neonatal Health and Biochemistry
  • Hypertrophic osteoarthropathy and related conditions
  • Chemotherapy-related skin toxicity
  • Radio Frequency Integrated Circuit Design
  • Gastrointestinal Tumor Research and Treatment
  • vaccines and immunoinformatics approaches
  • Sex and Gender in Healthcare
  • Colorectal and Anal Carcinomas
  • Hidradenitis Suppurativa and Treatments
  • Urticaria and Related Conditions
  • Fish Ecology and Management Studies
  • CAR-T cell therapy research
  • Calcium signaling and nucleotide metabolism
  • PARP inhibition in cancer therapy
  • Chemical Analysis and Environmental Impact
  • Cancer Immunotherapy and Biomarkers

USA Mitchell Cancer Institute
2025

University of South Alabama
2025

University of Virginia
2024

Syracuse University
1991

Johns Hopkins University
1990

Dihydronicotinamide rioside (NRH), the reduced form of nicotinamide riboside (NR), is a recently identified, naturally occurring precursor arguably most crucial cofactor for cellular function, adenine dinucleotide (NAD+). Recent investigation suggests that NRH more adept at increasing NAD+ stores than traditional precursors, and such extreme boosting via supplementation induces cytotoxicity in certain contexts. It has also been shown lack functional BRCA protein epithelial ovarian cancer...

10.3390/ijms26041719 article EN International Journal of Molecular Sciences 2025-02-18

Amino acid sequencing of glucose 6-phosphate dehydrogenase (Glc6PD) from Leuconostoc mesenteroides yielded sequence for over 75% the protein. Two oligonucleotides based on amino were used to isolate a partial Glc6PD gene clone (pLmz delta N65), pUC9 library, containing 85% coding and 3'-untranslated DNA, but lacking 5'-noncoding DNA portion encoding 65 N-terminal acids. Attempts obtain full-length lambda libraries unsuccessful, possibly due restriction L. by Escherichia coli host cells. The...

10.1016/s0021-9258(18)98798-3 article EN cc-by Journal of Biological Chemistry 1991-07-01

Biological females experience more autoimmune disease than males and treatment-related adverse events (TRAEs) after immune checkpoint blockade therapy. However, little is known about sex-related differences in TRAEs cancer vaccines.

10.3390/cancers16223882 article EN Cancers 2024-11-20

Background/Objective: Biological females experience more autoimmune disease than males and treatment-related adverse events (TRAEs) after immune checkpoint blockade therapy. However, little is known about sex-related differences in TRAEs cancer vaccines. Methods: The Mel44 clinical trial (NCT00118274) enrolled patients with high-risk melanoma to either of two We hypothesized that would higher rates grades TRAEs. TRAE were compared between sexes, adjustment for multiple comparisons,...

10.20944/preprints202410.1881.v1 preprint EN 2024-10-24

Page 21354, Fig. 4: The omission of a “G” was recently discovered in the nucleotide sequence winter flounder genomic clone p♀5.4. Inclusion (reverse-shaded below) results frameshift that extends open reading frame by 30 amino acids (GenBank™ accession number U03674).

10.1016/s0021-9258(18)61762-4 article EN cc-by Journal of Biological Chemistry 1998-03-01
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