A5032128811- Rheology and Fluid Dynamics Studies
- Polymer crystallization and properties
- Muscle Physiology and Disorders
- Elasticity and Material Modeling
- Cardiomyopathy and Myosin Studies
- Particle Accelerators and Free-Electron Lasers
- Polymer Foaming and Composites
- Signaling Pathways in Disease
- Particle Detector Development and Performance
- Particle accelerators and beam dynamics
- Particle physics theoretical and experimental studies
- Polymer Nanocomposites and Properties
- Material Properties and Processing
- Adipose Tissue and Metabolism
- Retinoids in leukemia and cellular processes
- High-Energy Particle Collisions Research
- Hormonal and reproductive studies
- Alkaline Phosphatase Research Studies
- Gyrotron and Vacuum Electronics Research
- Masonry and Concrete Structural Analysis
- Growth Hormone and Insulin-like Growth Factors
- Glycosylation and Glycoproteins Research
- Cellular Mechanics and Interactions
- Tissue Engineering and Regenerative Medicine
- Textile materials and evaluations
Medizinische Hochschule Hannover
2011-2025
Deutsches Elektronen-Synchrotron DESY
1997-2020
BASF (United States)
2016
University of Rostock
2009
ETH Zurich
1985-2007
Ion Beam Applications (Belgium)
1999
Krankenhaus St. Joseph-Stift Bremen
1999
Board of the Swiss Federal Institutes of Technology
1987-1998
University of Toledo
1998
École Polytechnique Fédérale de Lausanne
1979-1997
Abstract Improvements to the Weissenberg rheogoniometer are necessary in order measure transient rheological properties of polymer melts correctly. The improvements reported concern mechanical design, a new heating system, normal force measuring and additional equipment for relaxation test. Reliable short‐time results require sufficiently stiff torque springs, small radius relatively large angles cone‐and‐plate gap. behavior LDPE melt under test is “linear viscoelastic,” if shear rate or...
A recent development in extensional rheometry of molten polymers is based on the use a pair gears as ‘rotational clamp’. In tensile tester for polymer melts, rotational clamp provides draw-down melt being extruded out die indexer. The result quick characterization extensibility and strength. new rheometer, two clamps are used which extend homogeneously rod floating silicone oil bath. For constant speeds clamps, (Hencky) strain rate constant. creep test with stress can be performed same...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation J. Meissner, R. W. Garbella, Hostettler; Measuring Normal Stress Differences in Polymer Melt Shear Flow. Rheol. 1 August 1989; 33 (6): 843–864. https://doi.org/10.1122/1.550067 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown...
Abstract For small strains Lodge's rubberlike‐liquid theory is a valid description of the rheological behaviour polymer melts, but at higher fails: The phenomenon shear thinning which characteristic for flow nearly all liquids not explained, and in elongation deviation experimental data from predictions reflect also , strain hardening spite pronounced S‐shape stress‐strain diagrams. Comparing measured stress growth relaxation with theory, it must be concluded that temporary physical network...
In a new rheometer for polymer melts equibiaxial and planar elongations were performed at 150 °C with low high density polyethylene (LDPE HDPE, respectively), 170 commercial polystsyrene (PS); simple previously described was used. Each sample is clamped by metal belts that introduce the elongation measure forces act upon each clamp. The samples are small supported inert gas. By particle tracking video recording deformation history test performance determined. resulting elongational...
The calcineurin-mediated signal transduction via nuclear factor of activated T cells (NFATc1) is involved in upregulating slow myosin heavy chain (MHC) gene expression during fast-to-slow transformation skeletal muscle cells. This study aims to investigate the Ca2+ necessary activate calcineurin-NFATc1 cascade muscle. Electrostimulation primary myocytes from rabbit for 24 h induced a distinct at MHC mRNA level and full activation pathway, although resting concentration ([Ca2+]i) remained...
The field of fluid mechanics is rapidly advancing, driven by unprecedented volumes data from experiments, measurements, and large-scale simulations at multiple spatiotemporal scales. Machine learning (ML) offers a wealth techniques to extract ...Read More
Abstract Calcium is a key element in intracellular signaling skeletal muscle. Changes calcium levels are thought to mediate the fast‐to‐slow transformation of muscle fiber type. One factor implicated gene regulation adult nuclear activated T‐cells (NFAT) isoform c1, whose dephosphorylation by calcium/calmodulin‐dependent phosphatase calcineurin facilitates its translocation. Here, we report that differentiated C2C12 myotubes predominantly expressing fast‐type MyHCII protein undergo following...
The mitogen-activated protein kinase (MAPK)-activated kinases 2 and 3 (MK2/3) represent downstream of the p38 MAPK. Using MK2/3 double-knockout (MK2/3(-/-)) mice, we analyzed role in cross-striated muscle by transcriptome proteome analyses histology. We demonstrated enhanced expression slow oxidative skeletal myofiber gene program, including peroxisome proliferator-activated receptor gamma (PPARγ) coactivator 1α (PGC-1α). reporter electrophoretic gel mobility shift assays, that MK2 catalytic...
The addition of cyclosporin A (500 ng ml(-1)) - an inhibitor the Ca2+-calmodulin-regulated serine/threonine phosphatase calcineurin to primary cultures rabbit skeletal muscle cells had no influence on expression fast myosin heavy chain (MHC) isoforms MHCIIa and MHCIId at level protein mRNA, but reduced slow MHCI mRNA. In addition, citrate synthase (CS) glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA was found. enzyme activity CS also not affected. When Ca2+ ionophore A23187 (4 x 10(-7)...
Abstract For film blowing of polyethylene it has been shown previously that melt elongation is very powerful for polymer characterization. With two types rheometers, simple (also called “uniaxial”) elongational tests as well creep can be performed homogeneously. In elongation, the melts branched show a remarkable strain hardening. respect to their advantages and disadvantages, these rheometers complement each other. multiaxial elongations various modes deformation by means rotary clamp...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation B. Zülle, J. Linster, Meissner, H. P. Hürlimann; Deformation Hardening Thinning in Both Elongation Shear of a Low Density Polyethylene Melt. Rheol. 1 October 1987; 31 (7): 583–598. https://doi.org/10.1122/1.549937 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote...
We have investigated the previously published 'metabolon hypothesis' postulating that a close association of anion exchanger 1 (AE1) and cytosolic carbonic anhydrase II (CAII) exists greatly increases transport activity AE1. study whether there is physical direct functional interaction between CAII AE1 in native human red cell tsA201 cells coexpressing heterologous fluorescent fusion proteins CAII-CyPet YPet-AE1. In these doubly transfected cells, YPet-AE1 clearly associated with membrane,...