An operationally simple and green method for the synthesis of a wide range bis(indolyl)methanes, N,N'-alkylidene bisamides under mild conditions, with excellent yields using silzic, has been developed. This improved furnishes in good bis(indolyl)methanes derivatives starting from indole aldehydes, or ketones, acetamide aldehydes. catalytic system was reused up three times The same efficiency

This study focused on one traditional herb used in Yemen, Caralluma deflersiana. The antioxidant activity of the extracts was examined using bipyridine-ferric reducing capacity assay, as well antibacterial against S. aureus, P. aeruginosa, E. coli, and C. albicans microbial strains agar diffusion method. highest observed for ethyl acetate extract. 370 µg ASA/mg ascorbic equivalent (p< 0.05). Acetone chloroform showed decreased 340 305 equivalents ASA/mg, respectively. three inhibited...

A competent new one‐pot synthesis for tetrahydrobenzo[f]chromeno[3,2‐c]tetrazolo[1,5‐a]azepines through the catalytic of related xanthenes. β‐naphthol, dimedone, aromatic aldehydes were stirred under solvent free condition in presence tetrachlorosilane (TCS), then azidochlorosilane (which prepared situ from sodium azide and TCS acetonitrile as solvent) was added reaction at 50‐60 oC. molecular docking synthesized compounds carried out order to investigate their binding pattern with...

  Baking market is deriving the new technique to produce low fat foods due high demand from health conscious individuals. Fat replacement largely focused on rich food such as biscuit, cookies and cake etc. Rice bran broken rice are two major by-products of milling industry that contain important chemical properties moisture, hardness score, protein, fiber ash. The known percentages powder were mixed separately with wheat flour. impact substitution rheological behaviour, dough...

A green and highly efficient protocol for the one-pot synthesis of a variety 14-aryl-14-H-dibenzo [a,j]xanthenes 9-aryl-1,8-dioxo-octahydroxanthenes has been developed via cyclocondensation aryl aldehydes with 2-naphthol or dimedone using SiO 2 -ZnCl (silzic) as reusable heterogeneous catalyst under solvent-free reaction conditions.In addition, one-pot, threecomponent condensation aldehydes, ammonium acetate amines to furnish 9-aryl-1,8-dioxo-decahydroacridines in good excellent yields same...

Monolluma quadrangula (Forssk.) is a medicinal succulent plant belonging to the family Apocynaceae. The phytochemical examination of M. methanolic extract resulted in isolation three unique new pregnane glycosides, quadrangulosides G-I (1-3), their structures were elucidated utilising 1D, 2D NMR and ESI MS spectral studies. Pure sixteen isolated glycosides from tested for cytotoxicity against breast cancer cell lines (MCF-7) colon (HCT-116), using MTT assay doxorubicin as positive control....

The phytochemical investigation of Caralluma quadrangula aerial parts yielded six new pregnane glycosides, quadrangulosides A-F (1-6), in addition to nine known glycosides and three flavone glycosides. Structures isolated phyto-constituents were elucidated via spectroscopic 1D-, 2D-NMR spectrometric ESI-MS spectra.

This study aimed at estimating the total phenolic content, flavonoid content and evaluation of toxic effect chloroform aqueous methanol extracts Orbea wissmannii against WI38 HepG2 cell lines. was collected from Qaren region near Amran governorate, Yemen. Chloroform whole parts were prepared by maceration decantation. The polyphenol estimated using Folin–Ciocalteau method. Aluminum chloride colorimetric method applied for determination content. cytotoxic activity measured MTT assay. 70.21 mg...

Abstract Bis(indolyl)methanes are synthesized from indoles and aldehydes or ketones, while bis‐amides acetamide aldehydes.