Laura Pires

ORCID: 0009-0004-4131-0133
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About
Contact & Profiles
Research Areas
  • Lymphatic System and Diseases
  • Diagnosis and Treatment of Venous Diseases
  • Body Contouring and Surgery
  • Systemic Sclerosis and Related Diseases
  • Surgical Simulation and Training
  • Anatomy and Medical Technology
  • Nerve injury and regeneration

Centro de Cirugía de Mínima Invasión Jesús Usón
2022-2025

Abstract Introduction Peripheral nerve injuries affect numerous patients annually, with outcomes influenced by factors such as the nerve’s regenerative capacity, injury severity, and surgeon’s technical skill. Animal models are essential for refining surgical techniques exploring new therapies to improve regeneration. The choice of animal model depends on target nerve. This study describes a standardized rat sciatic defect model. Methods involves under deep anesthesia. lateral thigh area is...

10.1093/bjs/znae322.008 article EN British journal of surgery 2025-01-01

Lymphedema presents significant challenges to patients’ quality of life, prompting the exploration innovative treatments, such as collagen scaffolds, aimed at treating and reducing risk lymphedema. We evaluate preventive therapeutic efficacy lymphangiogenic potential implanted aligned nanofibrillar scaffolds (BioBridgeTM) following induction secondary lymphedema in a rabbit model. Thirty rabbits were divided into treatment (G1), prevention (G2), control (G3) groups. Secondary was induced all...

10.3390/jfb15080235 article EN cc-by Journal of Functional Biomaterials 2024-08-21

Lymphedema is a common condition often associated with cancer and its treatment, which leads to damage the lymphatic system, current treatments are mostly palliative rather than curative. Its high incidence among oncologic patients indicates need study both normal function pathologic dysfunction. To reproduce chronic lymphedema, it necessary choose suitable experimental animal. Attempts establish animal models limited by regenerative capacity of system. Among potential candidates, rabbit...

10.3791/64576 article EN Journal of Visualized Experiments 2022-11-30

Lymphaticovenous anastomosis is widely used in lymphedema management. Although its effectiveness reducing edema patients can be clinically observed, evaluating the long-term outcomes of this technique complex. This study established an animal model to assess lymphaticovenous at 15 and 30-days post-surgery using indocyanine green lymphography, Patent Blue V dye injection, histopathological examination.

10.1016/j.bjps.2024.04.023 article EN cc-by-nc-nd Journal of Plastic Reconstructive & Aesthetic Surgery 2024-04-13

Abstract Background Lymphedema is a chronic condition, characterized by fluid buildup and tissue swelling caused impairment of the lymphatic system. The lymph interpositional flap transfer technique, in which flow restored with that includes subdermal channels, an option for surgical reconstruction. superficial circumflex iliac artery perforator (SCIP) can be used this purpose. This study aimed to describe characterize patterns within vascular territory SCIP flap. Methods cross-sectional...

10.1055/a-2340-9629 article EN cc-by-nc-nd Journal of Reconstructive Microsurgery 2024-06-07
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