- Advanced Sensor and Energy Harvesting Materials
- Dysphagia Assessment and Management
- Conducting polymers and applications
- Tactile and Sensory Interactions
- Voice and Speech Disorders
- Muscle activation and electromyography studies
- Interactive and Immersive Displays
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Mechanical and Optical Resonators
- Organic Electronics and Photovoltaics
- Graphene research and applications
- Child Nutrition and Feeding Issues
- Advanced Chemical Sensor Technologies
- Nanomaterials and Printing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Electrochemical Analysis and Applications
- Supercapacitor Materials and Fabrication
- Organic Light-Emitting Diodes Research
- Renal and Vascular Pathologies
- Force Microscopy Techniques and Applications
- Electrohydrodynamics and Fluid Dynamics
- Nanowire Synthesis and Applications
- Salivary Gland Disorders and Functions
- Dielectric materials and actuators
University of California, San Diego
2013-2023
University of California System
2014-2020
La Jolla Alcohol Research
2014
University of San Diego
2014
The present work describes the first example of real-time noninvasive lactate sensing in human perspiration during exercise events using a flexible printed temporary-transfer tattoo electrochemical biosensor that conforms to wearer's skin. new skin-worn enzymatic exhibits chemical selectivity toward with linearity up 20 mM and demonstrates resiliency against continuous mechanical deformation expected from epidermal wear. device was applied successfully subjects for monitoring sweat dynamics...
We present a proof-of-concept demonstration of an all-printed temporary tattoo-based glucose sensor for noninvasive glycemic monitoring. The represents the first example easy-to-wear flexible epidermal diagnostic device combining reverse iontophoretic extraction interstitial and enzyme-based amperometric biosensor. In-vitro studies reveal tattoo sensor's linear response toward physiologically relevant levels with negligible interferences from common coexisting electroactive species....
A wearable mouthguard electrochemical biosensor for salivary metabolites is described. Such non-invasive metabolite biosensors provide real-time information regarding a wearer's health, performance and stress level, thus hold considerable promise diverse biomedical fitness applications.
The article reports on the fabrication of wearable textile biofuel cells integrated with energy storage device for powering electronics wearer’s perspiration as a fuel source.
A body-compliant epidermal rechargeable Ag–Zn printable tattoo battery is reported.
Increasing security needs require field-deployable, on-the-spot detection tools for the rapid and reliable identification of gunshot residue (GSR) nitroaromatic explosive compounds. This manuscript presents a simple, all-solid-state, wearable fingertip sensor on-site voltammetric screening GSR surface residues. To fabricate new Forensic Fingers, we screen-print three-electrode setup onto nitrile finger cot, coat another cot with an ionogel electrolyte layer. The integrated sampling/detection...
This paper describes effects of the flexibility, length, and branching side chains on mechanical properties low-bandgap semiconducting polymers. The backbones polymer comprise a diketopyrrolopyrrole (DPP) motif flanked by two furan rings copolymerized Stille polycondensation with thiophene (DPP2FT). DPP fall into three categories: linear alkyl (C8, C14, or C16), branched (ethylhexyl, EH, hexyldecyl, HD), oligo(ethylene oxide) (EO3, EO4, EO5). Polymers bearing C8 C14 are obtained in low...
Wearable mechanical sensors have the potential to transform healthcare by enabling patient monitoring outside of clinic. A critical challenge in development mechanical—e.g., strain—sensors is combination sensitivity, dynamic range, and robustness. This work describes a highly sensitive robust wearable strain sensor composed three layered materials: graphene, an ultrathin film palladium, plasticized PEDOT:PSS. The role graphene provide conductive, manipulable substrate for deposition...
Despite the common association of π-conjugated polymers with flexible and stretchable electronics, these materials can be rigid brittle unless they are designed otherwise. For example, low modulus, high extensibility, toughness treated as prerequisites for integration soft biological structures. One most successful commercially available organic electronic is conductive polyelectrolyte complex poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). To make this material...
There is a need to monitor patients with cancer of the head and neck postradiation therapy, as diminished swallowing activity can result in disuse atrophy fibrosis muscles. This paper describes flexible strain sensor comprising palladium nanoislands on single-layer graphene. These piezoresistive sensors were tested 14 disease-free various levels function: from nondysphagic severely dysphagic. The patch-like devices detected differences (1) consistencies food boluses when swallowed (2)...
Human ability to discriminate between hydrophilic and hydrophobic surfaces is attributed differences in vibrational frequencies generated while sliding at particular velocities normal forces.
Two current applications of metal nanoisland–graphene composites are shown.
Abstract A type of haptic device is described that delivers two modes stimulation simultaneously and at the same location on skin. The are mechanical (delivered pneumatically by inflatable air pockets embedded within a silicone elastomer) electrical conductive polymer). key enabling aspect this work use highly plasticized polymer based poly(3,4‐ethylenedioxythiphene) (PEDOT) blended with elastomeric polyurethane (PU). To fabricate “electropneumotactile” device, polymeric electrodes overlaid...
Most advantages of organic electronic materials are enabled by mechanical deformability, as flexible (and stretchable) devices made from these must be able to withstand roll-to-roll printing and survive insults the external environment. Cohesion adhesion two properties that dictate reliability a device. In this paper, progressive-load scratch tests used for first time correlate cohesive adhesive behavior poly(3-alkylthiophenes) (P3ATs) with respect molecular parameters: length alkyl side...
Despite the apparent convenience of microfluidic technologies for applications in healthcare, such devices often rely on capital-intensive optics and other peripheral equipment that limit throughput. Here, we monitored transit fluids, gases, particles, cells as they flowed through a channel without use camera or laser, i.e., "optics-free" microfluidics. We did this by monitoring deformation side walls caused analyte passing channel. Critically, not have to make contact with induce...
The purpose of this work is to clarify the mechanism piezoresistance in a class ultra-sensitive strain gauges based on metallic films 2D substrates (“2D/M” films).
Background Frequent sensor-assisted monitoring of changes in swallowing function may help improve detection radiation-associated dysphagia before it becomes permanent. While our group has prototyped an epidermal strain/surface electromyography sensor that can detect minute muscle movement, is unknown whether patients with head and neck cancer would be willing to wear such a device at home after radiation for several months. Objective We iteratively assessed patients’ design preferences...
<sec> <title>BACKGROUND</title> Frequent sensor-assisted monitoring of changes in swallowing function may help improve detection radiation-associated dysphagia before it becomes permanent. While our group has prototyped an epidermal strain/surface electromyography sensor that can detect minute muscle movement, is unknown whether patients with head and neck cancer would be willing to wear such a device at home after radiation for several months. </sec> <title>OBJECTIVE</title> We iteratively...