A5076534978- Neuroscience and Neural Engineering
- Photoreceptor and optogenetics research
- Hydrogels: synthesis, properties, applications
- Transcranial Magnetic Stimulation Studies
- Muscle activation and electromyography studies
- Neural dynamics and brain function
- Tissue Engineering and Regenerative Medicine
- Cardiac electrophysiology and arrhythmias
- Neurological disorders and treatments
- Photochromic and Fluorescence Chemistry
- Advanced Research in Systems and Signal Processing
- Perovskite Materials and Applications
- Hemodynamic Monitoring and Therapy
- Ion channel regulation and function
- Luminescence and Fluorescent Materials
- Sepsis Diagnosis and Treatment
- Organic Electronics and Photovoltaics
- Quantum Dots Synthesis And Properties
- Conducting polymers and applications
- Cardiac, Anesthesia and Surgical Outcomes
- Mass Spectrometry Techniques and Applications
- Electrospun Nanofibers in Biomedical Applications
- Cardiovascular and exercise physiology
Graz University of Technology
2022-2025
BioTechMed-Graz
2025
Medical University of Graz
2025
Abstract Organic photovoltaics show great potential for wireless bioelectronics, offering the ability to convert visible‐to‐near‐infrared light into electrical energy. This study investigates stability and biocompatibility of PM6:Y6 bulk heterojunction layers, chosen their efficient charge separation absorption profile compatible with optical transparency skin tissue, under simulated physiological conditions. Biocompatibility is validated using chicken chorioallantoic membrane cytotoxicity...
<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective:</i> This study aims to explore the potential of organic electrolytic photocapacitors (OEPCs), an innovative photovoltaic device, in mediating activation native voltage-gated Cav1.2 channels ( xmlns:xlink="http://www.w3.org/1999/xlink">I</i> Ca,L) Guinea pig ventricular cardiomyocytes. xmlns:xlink="http://www.w3.org/1999/xlink">Methods:</i> Whole-cell patch-clamp recordings were...
Abstract Neurostimulation employing photoactive organic semiconductors offers an appealing alternative to conventional techniques, enabling targeted action and wireless control through light. In this study, electrolytic photocapacitors (OEPC) are employed investigate the effects of light‐controlled electric stimulation on neuronal networks in vitro vivo. The interactions between devices biological systems characterized. Stimulation primary rat cortical neurons results elevated expression...
Abstract This study presents a finite element model (FEM) simulation of optoelectronic stimulation in the rat brain, designed to investigate effects this emerging neural technique. A detailed 3D brain and an equivalent circuit representation organic semiconductor-based device was used simulate subdural application stimuli brain. The is based on realistic electrode geometries material properties. stimulated volume approximately 38 mm3 with maximal depth 2.6 mm. Our results indicate that can...
Background: Surgical interventions can cause severe fluid imbalances in patients undergoing cardiac surgery, affecting length of hospital stay and survival. Therefore, appropriate management daily goals is a key element postoperative intensive care these patients. Because balance influenced by complex interplay patient-, surgery- unit (ICU)-specific factors, prediction difficult often inaccurate. Methods: A novel system theory based digital model for cumulative (CFB) presented using recorded...
Abstract Capacitive extracellular stimulation is a common method in implanted electrodes. The basis for investigating the transmission of stimuli from an electrode to adhered cells are vitro experiments using calcium imaging or patch clamp measurements. Computational spatial models used simulate mechanism signal at cell-electrode interface but require high computing power. In this work, Stern model characterize electrochemical double-layer (EDL) formation and modified two-domain combined...
Abstract This paper discusses possibilities to explain which Kv channels can be considered as first-order systems. means that the dynamic behavior of these described with a differential equation and are most straightforward dynamical For example, typical system is an RC circuit, analogously, systems following circuits. work represents family KV systems, providing efficient method ion channel modeling in computational electrophysiology.
Abstract Fluid flow in the human body can be modeled using a water-level tank, commonly used mechanistic approach mechanical engineering for fluid transport processes. Postoperative data from patients undergoing cardiac surgery is to estimate dynamics and total water body. This simplified model provide basic understanding of processes could aid modeling distribution fluids compartments.
Abstract In this study, we employed calcium imaging to investigate the dynamics of intracellular levels in embryonic chicken cardiomyocytes upon extracellular, optoelectronic stimulation. A photovoltaic layer donoracceptor pigments on a flexible PET substrate was used as wireless stimulation electrode. Our findings revealed distinct change their spontaneous activity pattern cardiac cells following asynchronous light short pause cellular activity, indicative overdrive suppression, observed...