A5048211398- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Mental Health Research Topics
- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Nerve injury and regeneration
- Personality Disorders and Psychopathology
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- COVID-19 and Mental Health
- Electroconvulsive Therapy Studies
- Tryptophan and brain disorders
- Eating Disorders and Behaviors
- Attention Deficit Hyperactivity Disorder
- Mental Health Treatment and Access
- Treatment of Major Depression
- Multiple Sclerosis Research Studies
- Adolescent and Pediatric Healthcare
- Employment and Welfare Studies
- Healthcare Decision-Making and Restraints
- Psychosomatic Disorders and Their Treatments
- Sleep and related disorders
- Intensive Care Unit Cognitive Disorders
- Suicide and Self-Harm Studies
- Infrared Thermography in Medicine
University of Cagliari
2014-2025
Agenzia Regionale Sanitaria della Puglia
2023
University of Southampton
2016
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2016
University of Milano-Bicocca
2016
Stanford University
2016
Fondazione Salvatore Maugeri
2011
The objective is to verify whether a genetic condition associated with bipolar disorder (BD) frequent in old adults adapted their environment, without BD, but aptitudes for hyperactivity and novelty seeking (H/NS).In this cross-sectional study, the study sample included healthy elderly people (40 participants, aged 60 or older) living an urban area recruited from previous on physical exercise active aging, who were compared 21 BD same area. methodology consisted of blood sampling, DNA...
This paper illustrates the preliminary psychometric properties of Questionnaire for Adaptive Hyperactivity and Goal Achievement (AHGA), aimed at measuring adaptive characteristics hyperactivity goal pursuit in older adults.The 12-item scale was administered to a sample 120 subjects (older adults) between February 2022 June 2022. The reliability AHGA measured using Cronbach's alpha, factor structure established parallel analysis (PA) principal component (PCA). Convergent validity tested...
The aim of this paper is to verify if people with a positive score on the Mood Disorder Questionnaire (MDQ) without comorbidity mood disorders showed worse level Health-related Quality life (HRQol) compared control-matched sample MDQ negatives, identifying specific syndrome. This case-control study based database from community survey. Cases: MDQ-positive disorders; Controls: negatives matched by sex, age, and psychiatric diagnosis according Diagnostic Statistical Manual Mental Disorders IV...
Background: Cognitive impairment is a frequent consequence of bipolar disorder (BD) that difficult to prevent and treat. In addition, the quality preliminary evidence on treatment BD through Remediation (CR) with traditional methods poor. This study aims evaluate feasibility CR intervention fully immersive Virtual Reality (VR) as an additional for offers data its efficacy. Methods: Feasibility randomized controlled cross-over clinical study, experimental condition lasting three months,...
Bipolar disorder (BD) is a relevant public health issue, therefore accurate screening tools could be useful. The objective of this study to verify the accuracy Mood Disorder Questionnaire (MDQ) and genetic risk as screeners, their comparison in terms reliability. Older adults (N = 61, ≥60 years) received clinical psychiatric evaluation, MDQ, were evaluated according presence variant RS1006737 CACNA1C. MDQ+ versus diagnosis BD gold standard shows sensitivity 0.286 (Cl 95% 0.14-0.39);...
A syndrome centered on the dysregulation of behavioral rhythms (DBR) is discussed. Recent pandemic brought to observe: (1) Having a DBR affecting sleep patterns, eating habits, and social interactions, before lockdown period, was determinant for depressive episodes during lockdown; (2) In tighter lockdowns, triggered in bipolar patients; (3) healthcare workers under pressure burnout; (4) influenced course chronic diseases by altering immune responses. addition, it found that scoring positive...
It is hypothesized that factors associated with bipolar disorder could, uer defined conditions, produce adaptive behaviors. The aim to verify whether a genetic feature can be found in people without but hyperactivity/exploration traits. Healthy old adults (N = 40) recruited for previous study on exercise were subdivided using previously validated tool into those and traits compared group of patients 21). variant RS1006737 CACNA1C was analyzed blood samples, DNA extraction, real-time PCR,...
Objective: The COVID-19 lockdown periods have given rise to the “Dysregulation of Mood, Energy, and Social Rhythms Syndrome” (DYMERS). This syndrome is characterized by a poor regulation biological, social, behavioral rhythms, including sleep, nutrition, social contacts. purpose this cohort study was examine whether older adults with pre-existing DYMERS had more negative perception their health-related quality life (H-QoL) during pandemic lockdown, regardless presence concurrent mood...
DSM-5 separates bipolar (BD) from depressive disorders, but some experts consider BD as part of a spectrum mood disorders. The interpretation numerous false positives screened by the Mood Disorders Questionnaire (MDQ) is this debate. Recent study results suggest that worsening health-related quality life (H-Qol) associated with MDQ positivity does not depend solely on This aims to clarify whether impairment may be due other concomitant unrelated leading H-Qol. Additionally, explore if itself...
Objective The aim of this work is to verify whether a cohort elderly people with hyper-energy tended increase depressive symptoms and misaligned social personal rhythms during the lockdown compared older adults without one year before lockdown. Methods two cohorts were evaluated in April 2019 (T0) 2020 (T1). Hyper-energy, cognitive performance, symptoms, at T0 T1. Results In measure Brief Social Rhythm Scale (BSRS) score, differences between groups observation times reach statistical...
Background/Objectives: Emerging laboratory technologies, such as breathomics, may enhance the early diagnosis of psychiatric disorders, including Bipolar Disorder (BD). This study investigates detection volatile sulfur compounds (VSCs) in exhaled breath potential biomarkers for BD, comparing VSC levels between individuals with healthy controls, and non-pathological hyperactivity. Methods: A matched case–control was conducted involving 24 patients BD 95 controls recruited at University...
Introduction: Achieving long-term impacts from cognitive remediation (CR) interventions is a key goal in rehabilitative care. Integrating virtual reality (VR) with psychoeducational approaches within CR programs has shown promise enhancing user engagement and addressing the complex needs of individuals bipolar disorder (BD). A previous randomized controlled crossover feasibility trial demonstrated viability fully immersive VR-CR intervention for BD, reporting low dropout rates, high...
Joint goniometry is a common mode of clinical assessment used in many disciplines, particular rehabilitation [1-3]. One way to perform joint through the use computer-aided measurements from digital photographs [4-8]. This method entails complex procedure obtain range motion (ROM) value, which consists picture being manipulated upon by dedicated software once it has been downloaded camera computer. Recently, new iPhone (Apple Inc, Cupertino, CA)-based application (app) functioning as virtual...
This study has investigated perceptions of respect for users' rights among informal caregivers in mental healthcare settings, aligning with the guidelines outlined United Nations Convention on Rights Persons Disabilities (CRPD) and World Health Organization QualityRights initiative. The employed questionnaire Well-being at Work Respect Human (WWRR) tested whether questionnaire's factor structure aligns that users health workers. We have hypothesized prioritize needs over care context's climate.
Background The present study aims to evaluate the preliminary content and face validity of “ Perceptions on Implementation CRPD in muniCIpalities Questionnaire (PICI-Q),” a self-report questionnaire built assess perceptions how effectively municipalities implement principles concerning social inclusion participation persons with disabilities municipalities. Methods A two-step Delphi methodology was used build its validity. group including health professionals, academics, experts...
BackgroundMentally ill people experience greater difficulty than the general population in exercising regularly.AimsWe aimed to evaluate attitudes displayed and barriers perceived towards physical activity a sample of psychiatric patients.MethodsA total 138 (M = 48, F 90) patients attending community mental health centre were compared with control group made up subjects not affected by disorders matched for gender, mean age education. Both groups underwent self-administered...
Studies performed to assess the relevance of duration untreated psychosis (DUP) as a predictor long-term outcome (i.e. follow-ups ten years or more) are somewhat limited. The aim this study was evaluate potential association between DUP and very (16-33 yrs) schizophrenia by means retrospective design.Retrospective data obtained from clinical records were collected regarding variables (number hospitalizations; number attempted suicides; course illness; GAF scores at last observation) for...
Background: Extensive research has explored SLE’s impact on health-related quality of life (H-QoL), especially its connection with mental wellbeing. Recent evidence indicates that depressive syndromes significantly affect H-QoL in SLE. This study aims to quantify H-QoL, accounting for comorbid episodes through case-control studies. Methods: A was conducted SLE patients (meeting the ACR/EULAR 2019 criteria age ≥ 18). The control group chosen from a community database. measured SF-12...
The respect for human rights in mental health care services significantly contributes to organizational well-being and is evolving into an actual benchmark of quality standards. This study assesses the perception users staff, as well job satisfaction among professionals three South American countries, through at work (WWRR) questionnaire whether there are significant differences. Seven facilities Argentina, Colombia, Peru were involved this observational study. sample comprised 310...
Introduction: Rehabilitative interventions employing technology play a crucial role in bipolar disorder (BD) treatment. The study aims to appraise the virtual reality (VR)-based cognitive remediation (CR) and interpersonal rhythm approaches treatment outcomes of BD across different age groups. Methods: Post-hoc analysis 12-week randomizedcontrolled cross-over feasibility trial involving people with mood disorders (BD, DSM-IV) aged 18–75 years old: thirty-nine exposed experimental VR-based CR...
Brain-derived neurotrophic factor (BDNF) is a key modulator of neuroplasticity and has an important role in determining the susceptibility to severe psychiatric disorder with significant neurodevelopmental component such as major psychoses. Indeed, potential association between BDNF serum levels schizophrenia (SCZ) schizoaffective (SAD) been tested diverse studies considerable amount them found reduced these disorders. Here, we aimed at testing several demographic, clinical, psychometric...