A5017652179- Urbanization and City Planning
- Hemoglobinopathies and Related Disorders
- Pregnancy and preeclampsia studies
- Local Government Finance and Decentralization
- Complement system in diseases
National Institute of Allergy and Infectious Diseases
2024
University of the West of England
1993
BACKGROUND: Severe malaria is associated with impaired nitric oxide (NO) synthase (NOS)–dependent vasodilation, and reversal of this deficit improves survival in murine models. Malaria might have selected for genetic polymorphisms that increase endothelial NO signaling now contribute to heterogeneity vascular function among humans. One protein potentially alpha globin, which, mouse models, interacts NOS (eNOS) negatively regulate signaling. We sought evaluate the impact globin gene deletions...
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