A5044611035- Antioxidant Activity and Oxidative Stress
- Photodynamic Therapy Research Studies
- Porphyrin and Phthalocyanine Chemistry
- Connexins and lens biology
- Advanced Glycation End Products research
- Phytochemicals and Antioxidant Activities
- Photochemistry and Electron Transfer Studies
- Bee Products Chemical Analysis
- Free Radicals and Antioxidants
- TiO2 Photocatalysis and Solar Cells
- Spectroscopy and Quantum Chemical Studies
- bioluminescence and chemiluminescence research
- Evaluation and Performance Assessment
- Genomics, phytochemicals, and oxidative stress
- Mineral Processing and Grinding
- Surfactants and Colloidal Systems
- Heavy Metal Exposure and Toxicity
- Hemoglobin structure and function
- Photosynthetic Processes and Mechanisms
- Hydrogen embrittlement and corrosion behaviors in metals
- Plant Genetic and Mutation Studies
- Glutathione Transferases and Polymorphisms
- Flavonoids in Medical Research
- Recycling and Waste Management Techniques
- Algal biology and biofuel production
Health Canada
2020-2024
University of Ottawa
2007-2011
University of California, Los Angeles
2004-2008
Loyola Marymount University
2008
Columbia University
2008
Institute for Chemical and Physical Processes
2004
Western University
1999-2004
Singlet oxygen quantum yields generated by excited state aromatic amino acids (tryptophan, tyrosine, phenylalanine), N-acetylated (N-acetyl-tryptophan, N-acetyl-tyrosine, N-acetyl-phenylalanine), and from selected proteins immunoglobulins have been quantified time-resolved phosphorescence measurements. A small, but significant, yield found for demonstrates that molecular can diffuse through the polypeptide matrix be sensitized residues buried within folds of protein structure.
In a regulatory context, it is important to understand how effective risk communication fits into the overall assessment, management, and decision-making process. This includes recognizing intersections between analysis 3Ps: policy, politics, publics, understanding barriers communication. Risk especially challenging when requires audience follow act on authoritative information or advice. communicators must factor attributes such as perception, tolerance, behaviors, tailor delivery of...
The interactions between chlorophyll a and two beta-cyclodextrins, that have the same cavity size but different substituents, were studied in aqueous solutions. These supramolecular host-guest complexes examined by combination of UV/vis absorption, circular dichroism, NMR, steady-state time-resolved fluorescence measurements. results indicate all cyclodextrins solubilize pigment mainly monomeric form water. forms 1:1 with heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin 1:2...
To correlate the oxidative state of postabsorptive blood plasma after consumption one or three drinks different beverages with known J-shaped epidemiological risk curves.Red wine, lager beer, stout (alcoholic and alcohol-free), antioxidant activity, an aqueous solution alcohol were compared for pro-oxidant activity in human volunteers following typical containing equivalent amounts (except alcohol-free used as a control stout).One drink red (5% v/v, alcohol-free) significantly increased...
It has been reported in the epidemiological literature that cataract, stroke, and atherosclerosis risk is reduced by 50% people consuming one alcoholic drink per day. Peroxide implicated as a causative agent cataractogenesis, LDL oxidation appears to play role atherosclerosis. The antioxidant activity of alcohol was measured by: (i) use luminescent assay developed our laboratory, confirmed appropriate; (ii) electron spin resonance (ESR) spin-trapping; (iii) copper-catalysed VLDL from...
We report a novel method of identifying damage to DNA leading the loss intercalation sites. Thiazole orange (TO), an intercalating cyanine dye, fluoresces strongly when intercalated in DNA, but not free solution. Upon UVC-induced change TO fluorescence is greater than any other spectral or biochemical indicators (absorbance, circular dichroism and agarose gel electrophoresis), thus providing fast screening identify DNA. The geared toward high levels damage, such as those that may result...
<h3>Abstract</h3> <b>Background:</b> Moderate consumption of alcoholic drinks seems to reduce the risks developing cardiovascular disease, stroke, and cataracts, perhaps through antioxidant actions their alcohol, flavonoid, or polyphenol contents. “Shaken, not stirred” routinely identifies way famous secret agent James Bond requires his martinis. <b>Objectives:</b> As Mr is afflicted by cataracts an investigation was conducted determine whether mode preparing martinis has influence on...
Consumer personal care products, and cosmetics containing nanomaterials (NM), are increasingly available in the Canadian market. Current regulations do not require product labeling for ingredients that present nanoscale. As a result, unless voluntarily disclosed, it is unclear which products contain NM. The enhanced dark-field hyperspectral imaging (EDF-HSI) coupled with spectral angle mapping (SAM) recent technique has shown much promise detection of NM complex matrices. In study, EDF-HSI...
Determining whether alpha-crystallin (the major lens protein) affects the photophysics of hypericin, a photosensitizing agent found in various plants, such as St. John's Wort, is important. Hypericin shows promise cancer and human immunodeficiency virus therapy but may harm individuals taking Wort extracts (for mild to moderate depression). causes hypericism, which characterized by cellular damage light-exposed areas. Ocular tissues are at risk for photosensitized damage; thus, we...
Abstract Determining whether α‐crystallin (the major lens protein) affects the photophysics of hypericin, a photosensitizing agent found in various plants, such as St. John's Wort, is important. Hypericin shows promise cancer and human immunodeficiency virus therapy but may harm individuals taking Wort extracts (for mild to moderate depression). causes hypericism, which characterized by cellular damage light‐exposed areas. Ocular tissues are at risk for photosensitized damage; thus, we...