- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Aortic aneurysm repair treatments
- Long-Term Effects of COVID-19
- Psychology of Moral and Emotional Judgment
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Retirement, Disability, and Employment
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Psychosomatic Disorders and Their Treatments
- Intensive Care Unit Cognitive Disorders
- Neuroscience, Education and Cognitive Function
- Healthcare Decision-Making and Restraints
- Behavioral and Psychological Studies
- Electroconvulsive Therapy Studies
Massachusetts General Hospital
2015-2022
McLean Hospital
2022
Harvard University
2014-2022
University of Virginia
2018-2019
Electrodermal activity (EDA) is a measure of physical arousal, which frequently measured during psychophysical tasks relevant for anxiety disorders. Recently, specific protocols and procedures have been devised in order to examine the neural mechanisms fear conditioning extinction. EDA reflects important responses associated with stimuli specifically administrated these procedures. Although several previous studies demonstrated reproducibility measures estimated from EDA, mathematical...
Abstract Skin conductance response (SCR) is often used as an index of conditioned fear. SCR has been shown to be highly variable, and absence SC reactivity sometimes criteria for excluding data. It is, however, possible that low or no the result a distinct biological signature underlies individual differences in reactivity. This study examined neural correlates associated with near conditionability. Archival data from 109 healthy adults aged 18–60 years were pooled. All individuals had...
Introduction: Abdominal aortic aneurysm (AAA) rupture has a mortality rate of 64% and intracranial (IA) 50%. Despite the high rates, early detection treatment these vascular lesions prior to can prevent devastating clinical outcomes, underscoring need identify high-risk populations for screening. Current evidence demonstrates shared genetic environmental risk factors both AAA IA. Methods: The BAAS study sought establish co-prevalence In one arm BAAS, we recruited patients presenting with...
Background: The risk for intracranial (IA) and abdominal aortic aneurysms (AAA) is partially heritable, with evidence mounting in favor of shared genetic both. Methods: Brain Aortic Aneurysm Study (BAAS, NCT#17341) at University Virginia seeks to determine the coprevalence IA AAA recruiting patients presenting an aneurysm one site screening other. Participants undergo interview where clinical, demographic, radiographic data are collected. Recruitment ongoing, so preliminary demographic...
Introduction: Aneurysm rupture is associated with high mortality and morbidity, including both intracranial aneurysms (IA) abdominal aortic (AAA). Despite potential preemptive treatment in those identified prior to IA or AAA rupture, the evidence for whom screen remains limited. share environmental genetic risk, cost-effectiveness models suggest efficacy of screening these high-risk individuals. We hypothesized that reciprocal presenting would yield positive results. Methods: The BAAS study...