A5028608156- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Nutritional Studies and Diet
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Nutrition and Health in Aging
- Food Security and Health in Diverse Populations
- BRCA gene mutations in cancer
- Survey Methodology and Nonresponse
- Ethics in Clinical Research
- Obesity, Physical Activity, Diet
- Physical Activity and Health
- Childhood Cancer Survivors' Quality of Life
- Colorectal Cancer Treatments and Studies
- Diet and metabolism studies
- Cancer survivorship and care
- Musculoskeletal pain and rehabilitation
- Economic and Financial Impacts of Cancer
- Prenatal Screening and Diagnostics
- Multiple and Secondary Primary Cancers
- Cancer-related Molecular Pathways
- Smoking Behavior and Cessation
- Cancer Genomics and Diagnostics
- Myofascial pain diagnosis and treatment
- Obesity and Health Practices
University of Utah
2008-2024
Norfolk and Norwich University Hospital
2019
St Michael’s Hospital
2019
National Health Service
2019
University Hospitals of Leicester NHS Trust
2019
National Institute for Health Research
2019
Liverpool Womens NHS Foundation Trust
2019
Queen Charlotte's and Chelsea Hospital
2019
Newcastle upon Tyne Hospitals NHS Foundation Trust
2019
North Bristol NHS Trust
2019
BackgroundFetal structural anomalies, which are detected by ultrasonography, have a range of genetic causes, including chromosomal aneuploidy, copy number variations (CNVs; detectable microarrays), and pathogenic sequence variants in developmental genes. Testing for aneuploidy CNVs is routine during the investigation fetal but there little information on clinical usefulness genome-wide next-generation sequencing prenatal setting. We therefore aimed to evaluate proportion fetuses with...
Study Design. A comparative study of cervical range motion in asymptomatic persons and those with whiplash. Objectives. To compare the primary conjunct ranges spine persistent whiplash-associated disorders, to investigate ability these measures discriminate between groups. Summary Background. Evidence that is an effective indicator physical impairment not conclusive. Few studies have evaluated whiplash on basis or compared three-dimensional vivo disorders. Methods. The participants were 89...
BackgroundThe growing demand for cancer genetic services underscores the need to consider approaches that enhance access and efficiency of counseling. Telephone delivery may improve these individuals experiencing geographic (rural areas) structural (travel time, transportation, childcare) barriers access.
Journal Article Objective System for Interviewer Performance Evaluation Use in Epidemiologic Studies Get access Sandra Edwards, Edwards 1Department of Family and Preventive Medicine, University Utah School MedicineSalt Lake City, UT Reprint requests to Department 50 N. Medical Drive, Salt 84132 Search other works by this author on: Oxford Academic PubMed Google Scholar Martha L. Slattery, Slattery Motomi Mori, Mori T. Dennis Berry, Berry Bette J. Caan, Caan 2Kaiser Permanente Care...
Studies of the etiology colon cancer indicate that it is strongly associated with diet and lifestyle factors. The authors use data from a population-based study conducted in northern California, Utah, Minnesota 1991–1995 to determine patterns their association cancer. Data obtained 1,993 cases 2,410 controls were grouped by using factor analyses describe various aspects patterns. first five for both men women loaded heavily on dietary variables labeled: "Western," "moderation,"...
PURPOSE: Differences in acquired mutations colon and rectal tumors may account for differences risk factors. In this study, we examined similarities somatic alterations tumors. METHODS: Cases were identified from two large population-based case-control studies of cancer cancer. We sequenced Exons 5 to 8 the p53 gene Codons 12 13 Ki-ras identify tumor mutations. Microsatellite instability was determined based on BAT26 TGFβRII analysis; CpG island methylator phenotype having or more following...
Objective: To investigate pressure pain thresholds [PPTs] at sites both within and remote to the region involved with whiplash trauma.Methods: One hundred fifteen subjects chronic associated disorder [WAD] 95 healthy asymptomatic were included in study. Pressure measured eight bilaterally cervical spine upper limbs a site lower limb.Results: Subjects WAD had significantly PPTs than local [all P < 0.001]. There was greater decrease of over either or limb sites.Conclusion: The generalized...
Cultural differences in diet and lifestyle patterns probably contribute to cancer rates among ethnic groups the United States. In this paper, we describe physical activity of Hispanic non-Hispanic white women living southwestern States effects these on obesity.We use data from population-based controls (N = 2039) participating 4-Corner's Breast Cancer Study evaluate associations between language acculturation associated obesity.The majority both did not perform 30 min > or 5 d x wk(-1),...
Abstract Background Childhood cancers typically require rigorous treatment at specialized centers in urban areas, which can create substantial challenges for families residing remote communities. We evaluated the impact of residence and travel time on burden care childhood cancer patients. Procedure conducted a cross‐sectional, self‐administered survey 354 caregivers pediatric patients children's hospital serving seven state area. Measures included relocation, employment, schooling,...
Purpose The rate of adherence to regular colonoscopy screening in individuals at increased familial risk colorectal cancer (CRC) is suboptimal, especially among rural and other geographically underserved populations. Remote interventions may overcome geographic system-level barriers. We compared the efficacy a telehealth-based personalized assessment communication intervention with mailed educational brochure for improving at-risk relatives patients CRC. Methods Eligible age 30 74 years who...
Abstract Some studies have reported that p53 mutations or certain types of mutation are associated with poor prognosis in colon cancer, while other failed to show such a relationship. None these previous was population‐based. We therefore evaluated the prognostic significance large, population‐based study 1,464 individuals cancer from Utah and California. Mutations exons 5–8 were detected by SSCP analysis, followed sequencing aberrant bands. identified cancers 665 (45.4%) individuals....
Abstract Disturbances in DNA methylation have been hypothesized as being involved carcinogenesis. It has proposed that dietary factors such folate, alcohol, and methionine may be associated with colon cancer because of their involvement processes. Data from a large retrospective population‐based case‐control study incident were used to evaluate whether intake alcohol other are cancer. Dietary data obtained using detailed diet history questionnaire. We did not observe strong independent...
Smoking cigarettes has been consistently associated with adenomatous polyps. However, only a few studies have reported associations between smoking or using other forms of tobacco and colon cancer. A population-based case-control study cancer was conducted in 3 areas the United States: northern California, Utah Minnesota. We observed approximately 50% increase risk from over pack per day among both men women. Those who stopped remained at increased risk, even if they 10 years ago. Our data...
This study compared the neuromuscular efficiency (NME) of sternocleidomastoid (SCM) and anterior scalene (AS) muscles between 20 chronic neck pain patients asymptomatic controls.Myoelectric signals were recorded from sternal head SCM AS as subjects performed sub-maximal isometric cervical flexion contractions at 25 50% maximum voluntary contraction (MVC). The NME was calculated ratio MVC corresponding average rectified value EMG signal. Ultrasonography used to measure subcutaneous tissue...