A5092582832- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Bone Tissue Engineering Materials
- Additive Manufacturing Materials and Processes
- Ultrasound and Hyperthermia Applications
- Surgical site infection prevention
- Thermography and Photoacoustic Techniques
- Electrophoretic Deposition in Materials Science
Rush University Medical Center
2023-2024
Politecnico di Milano
2023
This experimental study aimed to characterize the thermal properties of ex vivo porcine and bovine kidney tissues in steady-state heat transfer conditions a wider interval (23.2–92.8 °C) compared previous investigations limited 45 °C. Thermal properties, namely conductivity (k) diffusivity (α), were measured temperature-controlled environment using dual-needle probe connected commercial property analyzer, transient hot-wire technique. The estimation measurement uncertainty was performed...
We created TiO 2 nanotubes (TNTs) on the surface of titanium (Ti) implants with subsequential loading gentamicin and chitosan, acting as a control release agent, by electrophoretic deposition (EPD). hypothesized femoral TNTs loaded chitosan would localize antibiotic to implant surgical site prevent PJI in mouse model. Ti-6Al-4V ELI wires underwent TNT modification two-step anodization. EPD was then used load onto Ti wire TNTs. Control contained only. 12-week-old male C57BL/6J mice received...
ABSTRACT Periprosthetic joint infection (PJI) is a leading cause and major complication of replacement failure. As opposed to standard‐of‐care systemic antibiotic prophylaxis for PJI, we developed tested titanium femoral intramedullary implants with titania nanotubes (TNTs) coated the gentamicin slow‐release agent chitosan through electrophoretic deposition (EPD) in mouse model PJI. We hypothesized that these would enable local delivery implant surface surgical site, effectively preventing...