Xingen Zhang

ORCID: 0009-0004-7363-4554
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About
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Research Areas
  • Plant Stress Responses and Tolerance
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant Molecular Biology Research
  • Genetics and Plant Breeding
  • Plant Gene Expression Analysis
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Hedgehog Signaling Pathway Studies
  • Photosynthetic Processes and Mechanisms
  • Neurofibromatosis and Schwannoma Cases
  • Biological and pharmacological studies of plants
  • Wnt/β-catenin signaling in development and cancer
  • Connective tissue disorders research
  • Plant nutrient uptake and metabolism
  • Plant Virus Research Studies
  • RNA Research and Splicing
  • Axon Guidance and Neuronal Signaling
  • Powder Metallurgy Techniques and Materials
  • Sarcoma Diagnosis and Treatment
  • RNA regulation and disease
  • Cholinesterase and Neurodegenerative Diseases
  • Coastal wetland ecosystem dynamics
  • Spinal Fractures and Fixation Techniques
  • Developmental Biology and Gene Regulation
  • Plant responses to water stress

West Anhui University
2023-2025

Anhui Agricultural University
2018-2023

Beijing Children’s Hospital
2008

Capital Medical University
2008

Heterosis is the superior performance of F1 hybrids relative to their parental lines for a wide range traits. In this study, expression profiling and heterosis associated genes were analyzed by RNA sequencing (RNA-Seq) in seedlings maize hybrid An'nong 591 its under control heat stress conditions. Through performing nine pairwise comparisons, maximum number differentially expressed (DEGs) was detected between two lines, minimum identified paternal both conditions, which suggested greater...

10.1186/s12870-019-1878-8 article EN cc-by BMC Plant Biology 2019-06-24

Maize (Zea mays L.) is the most essential food crop in world. However, maize highly susceptible to drought stress, especially at seedling stage, and molecular mechanisms underlying tolerance remain elusive. In this study, we conducted comparative transcriptome physiological analyses of drought-tolerant (CML69) (LX9801) inbred lines subjected treatment stage for three five days. The tolerant line had significantly higher relative water content leaves, as well lower electrolyte leakage...

10.3390/ijms22136980 article EN International Journal of Molecular Sciences 2021-06-29

Abstract The neurofibromatosis type 2 ( NF2 ) gene, known for encoding the tumor suppressor protein Merlin, is central to study of tumorigenesis and associated cellular processes. This review comprehensively examines multifaceted role /Merlin, detailing its structural characteristics, functional diversity, involvement in various signaling pathways such as Wnt/β‐catenin, Hippo, TGF‐β, RTKs, mTOR, Notch, Hedgehog. These are crucial growth, proliferation, differentiation. mutations specifically...

10.1096/fj.202400019rr article EN The FASEB Journal 2024-07-05

Skeletal mesenchymal stem cells (MSCs) possess self-renewal capacities and play a leading role in the craniofacial system. However, their engagement controlling cranial bone development regeneration remains largely unidentified. Herein, we discovered neurofibromin 2 (Nf2)-encoded regulator Merlin, demonstrating indispensableness Mice lacking Nf2 MSCs exhibit malformed bones, diminished proliferation, increased apoptosis, more severe osteogenesis impairment. Mechanically, substantiate that...

10.1038/s41467-025-57808-4 article EN cc-by-nc-nd Nature Communications 2025-03-12

Background: With global warming and climate change, the occurrence of abiotic stresses has become increasingly prevalent. Drought often occurs with high temperatures, especially in arid semi-arid regions. However, molecular mechanisms plants responding to combined drought high-temperature stress remains unclear. Results: Through integrative physiological, transcriptomic, metabolomic analyses, we systematically investigated adaptive Dendrobium huoshanense under stress. Our findings revealed...

10.3390/genes16030287 article EN Genes 2025-02-27

As an important food crop and nutritional source, mungbean has prioritized yield improvement as a key objective in breeding programs. In present study, we conducted QTL meta-analysis to integrate 660 QTLs related yield-related traits published over the past 20 years. A total of 590 initial were mapped onto high-density consensus map, resulting identification 72 meta-QTLs (MQTLs). These MQTLs unevenly distributed across 11 linkage groups (LGs) with average confidence interval (CI) 1.21 cM,...

10.3389/fgene.2025.1600979 article EN cc-by Frontiers in Genetics 2025-05-08

Improving barley grain quality is a major goal in breeding. In this study, total of 35 papers focusing on quantitative trait loci (QTLs) mapping for traits published since 2000 were collected. Among the 454 QTLs identified these studies, 349 them mapped onto high-density consensus maps, which used QTL meta-analysis. Through meta-analysis, initial integrated into 41 meta-QTLs (MQTLs) with an average confidence interval (CI) 1. 66 cM, 88.9% narrower than that QTLs. MQTLs, 25 subsequently...

10.3389/fpls.2023.1319889 article EN cc-by Frontiers in Plant Science 2024-01-11

Maize (Zeamays L.) is an essential food crop worldwide, but it highly susceptible to salt stress, especially at the seedling stage. In this study, we conducted physiological and comparative transcriptome analyses of seedlings maize inbred lines An'nong876 paternal (cmh15) maternal (CM37) under stress. The cmh15 were more salt-tolerant had higher relative water content, lower electrolyte leakage, malondialdehyde levels in leaves than CM37. We identified 2559 upregulated 1770 downregulated...

10.3390/ijms23095231 article EN International Journal of Molecular Sciences 2022-05-07

Drought-induced 19 (Di19) family genes play important roles in plant growth, development, and environmental stress responses. However, little is known about this maize. The upstream regulatory network of Di19 remains poorly understood response, especially. In study, seven ZmDi19 were identified, sequence alignment, gene structure, phylogenetic analysis was conducted. According to the analysis, ZmDi19-5 promoter cloned multiple putative stress-responsive cis-acting elements (CAEs) found...

10.3390/ijms23137390 article EN International Journal of Molecular Sciences 2022-07-02

BACKGROUND Foraminal puncture is a key step in foraminal endoscopic surgery, but the radiation dosage poses clinical risk to patients. To reduce dosage, we investigated feasibility and effect of transforaminal through use musculoskeletal ultrasound-guided lumbar percutaneous posterolateral approach. MATERIAL AND METHODS Retrospective data 80 approach surgery patients from March 2018 June 2021 were analyzed. The efficacy was assessed by visual analogue scale (VAS) Oswestry disability index...

10.12659/msm.937692 article EN Medical Science Monitor 2023-02-07
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