- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Animal Behavior and Reproduction
- Pharmacological Effects and Assays
- Analytical Chemistry and Chromatography
- Food Quality and Safety Studies
- Plant Molecular Biology Research
- Insect-Plant Interactions and Control
- Evolution and Genetic Dynamics
- Genetic Mapping and Diversity in Plants and Animals
- Orthoptera Research and Taxonomy
- Pesticide and Herbicide Environmental Studies
- Plant Parasitism and Resistance
- Horticultural and Viticultural Research
- Bacterial Genetics and Biotechnology
- Plant Reproductive Biology
- Soybean genetics and cultivation
- Coccidia and coccidiosis research
- Domain Adaptation and Few-Shot Learning
- Plant Physiology and Cultivation Studies
- Analytical Methods in Pharmaceuticals
- Phytochemistry and Biological Activities
- Analytical chemistry methods development
- Animal Nutrition and Physiology
- Veterinary medicine and infectious diseases
Tianjin Normal University
2023-2025
Jilin Agricultural University
2025
Taiyuan Normal University
2023-2025
Shanghai Ocean University
2024
University of St Andrews
2019-2024
Qingdao Agricultural University
2022
Shenyang Agricultural University
2022
Horticultural Research Institute
2022
Northeastern University
2021
Dalian Medical University
2021
Abstract Yak domestication represents an important episode in the early human occupation of high-altitude Qinghai-Tibet Plateau (QTP). The precise timing is debated and little known about underlying genetic changes that occurred during process. Here we investigate genome variation wild domestic yaks. We detect signals selection 209 genes yaks, several which relate to behaviour tameness. date yak 7,300 years before present (yr BP), most likely by nomadic people, estimated sixfold increase...
Tree peony (Paeonia ostii) is an economically important ornamental plant native to China. It also notable for its seed oil, which abundant in unsaturated fatty acids such as α-linolenic acid (ALA). Here, we report chromosome-level genome assembly (12.28 Gb) of P. ostii. In contrast monocots with giant genomes, tree does not appear have undergone lineage-specific whole-genome duplication. Instead, explosive LTR expansion the intergenic regions within a short period (~ two million years) may...
Livestock on the Qinghai-Tibetan Plateau is of great importance for livelihood local inhabitants and ecosystem plateau. The natural, harsh environment has shaped adaptations livestock while providing them with requisite eco-services. Over time, unique genes metabolic mechanisms (nitrogen energy) have evolved which enabled yaks to adapt morphologically physiologically Plateau. rumen microbiota also co-evolved host contributed host's adaptation environment. Understanding complex linkages...
Copy number variation (CNV) represents an important source of genetic divergence that can produce drastic phenotypic differences and may therefore be subject to selection during domestication environmental adaptation. To investigate the evolutionary dynamics CNV in yak genome, we used a read depth approach detect based on genome resequencing data from 14 wild 65 domestic yaks determined regions related adaptations high-altitude. We identified 2,634 (CNVRs) comprising total 153 megabases (5.7...
In the present study, four Lactobacillus strains from cheese were analyzed for its probiotic potential against enteropathogenic bacteria. The properties of selected also and bacterial showed high tolerance in bile salts organic acid. strain L. plantarum LP049 maximum survival rate (92 ± 4.2% 93.3 2%) after 3 h treatment at 0.25% (w/v) acid concentrations. ability to adhere human epithelial cells (HT-29 cell lines) was evaluated adhesion property (19.2 1.1%) than other tested strains....
Abstract Gene flow is predicted to impede parallel adaptation via de novo mutation, because it can introduce pre-existing adaptive alleles from population population. We test this using Hawaiian crickets ( Teleogryllus oceanicus ) in which ‘flatwing’ males that lack sound-producing wing structures recently arose and spread under selection an acoustically-orienting parasitoid. Morphometric genetic comparisons identify distinct flatwing phenotypes populations on three islands, localized...
Abstract Insects have evolved a diversity of regulatory mechanisms to determine their sex. Understanding the molecular regulation insect sex determination is great significance in revealing general law and providing potential routes for genetic manipulation pest species. Although cascade doublesex ( dsx ) gene functions been well described some holometabolous insects, little known about this hemimetabolous insects. In study, we identified homolog Gryllus bimaculatus , which belongs...
Organisms living at high altitudes must overcome three major environmental challenges: hypoxia, cold, and intense UV radiation. The molecular mechanisms that enable these challenges to be have mainly been studied in endothermic organisms; relatively little attention has paid poikilothermic species. Here, we present deep transcriptome sequencing two closely related lizards, the altitude-dwelling Phrynocephalus erythrurus lowland-dwelling P. putjatia, identify candidate genes under positive...
Abstract Evolutionary adaptation is generally thought to occur through incremental mutational steps, but large leaps can during its early stages. These are challenging study in nature due the difficulty of observing new genetic variants as they arise and spread, characterizing their genomic dynamics important for understanding factors favoring rapid adaptation. Here, we report consequences recent, adaptive song loss a Hawaiian population field crickets (Teleogryllus oceanicus). A discrete...
Urban greening provides important ecosystem services and ideal places for urban recreation is a serious consideration municipal decision-makers. Among the tree species cultivated in green spaces, Robinia pseudoacacia stands out due to its attractive flowers, fragrances, high trunks, wide adaptability, essential services. However, genomic basis consequences of wide-planting spaces remains unknown. Here, we report chromosome-level genome assembly R. pseudoacacia, revealing size 682.4 Mb 33,187...
Purpose: The function of curcumin on the gastric cancer cell line, SGC-7901 is unknown. present study aimed to observe effects cells through Shh and Wnt signaling pathways. Methods: were transfected with si-Gli1 si-β-catenin siRNA, then stimulated its migration, invasion, cytoskeleton remodeling, EMT, apoptosis cycle investigated by transwell assays, immunofluorescence flow cytometry assays. interaction between Gli1 β-catenin was observed co-immunoprecipitation. Results: We show that...
Abstract Theory predicts that compensatory genetic changes reduce negative indirect effects of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a wild population Hawaiian crickets using temporal genomics and high-quality chromosome-level cricket genome. In population, mutation, flatwing , silences males rapidly spread due to an acoustically-orienting parasitoid. Our sampling spanned social transition which fixed the went silent. We find long-range...
Cross-modal retrieval maps data under different modality via semantic relevance. Existing approaches implicitly assume that pairs are well-aligned and ignore the widely existing annotation noise, i.e., noisy correspondence (NC). Consequently, it inevitably causes performance degradation. Despite attempts employ co-teaching paradigm with identical architectures to provide distinct perspectives, differences between these primarily stemmed from random initialization. Thus, model becomes...
Cross-modal retrieval maps data under different modalities via semantic relevance. Existing approaches implicitly assume that pairs are well-aligned and ignore the widely existing annotation noise, i.e., noisy correspondence (NC). Consequently, it inevitably causes performance degradation. Despite attempts employ co-teaching paradigm with identical architectures to provide distinct perspectives, differences between these primarily stem from random initialization. Thus, model becomes...
As an important food crop and nutritional source, mungbean has prioritized yield improvement as a key objective in breeding programs. In present study, we conducted QTL meta-analysis to integrate 660 QTLs related yield-related traits published over the past 20 years. A total of 590 initial were mapped onto high-density consensus map, resulting identification 72 meta-QTLs (MQTLs). These MQTLs unevenly distributed across 11 linkage groups (LGs) with average confidence interval (CI) 1.21 cM,...
Semen cassiae is the ripe seed of Cassia obtusifolia L. or tora family Leguminosae. In traditional Chinese medicine, two forms are raw (R-SC) and parched (P-SC). To clarify processing mechanism cassiae, pharmacokinetics R-SC P-SC extracts were examined. A simple, rapid, sensitive ultra-high-performance liquid chromatography-tandem mass spectroscopy (UPLC-MS/MS) method was developed validated for simultaneous determination seven anthraquinone aglycones (aurantio-obtusin, obtusifolin, questin,...
Programmed cell death (PCD) systems have been extensively studied for their significant role in a variety of biological processes eukaryotic organisms. Recently, more and researches revealed the existence similar employed by bacteria response to various environmental stresses. This paper summarized recent researching advancements toxin/antitoxin located on plasmids or chromosomes regulatory roles bacterial PCD. The most yet disputed mazEF system was discussed depth, possible status such...
Cotton plant architecture, including fruit branch formation and flowering pattern, influences light exploitation, cotton yield planting cost. DNA methylation has been widely observed at different developmental stages in both plants animals is associated with regulation of gene expression, chromatin remodelling, genome protection other functions. Here, we investigated the global epigenetic reprogramming during development fruiting branches floral buds three stages: seedling stage,...
Lonicerae Japonicae Flos is often adulterated with Flos, which derived from the other four Lonicera species, in both crude drug and preparations. We proposed a methodology for quantitative analysis of adulterant Taking macranthoidins A, B, dipsacoside B (saponins), sweroside (iridoids), luteolin-7-O-d-glucoside (flavonoids) as markers, method ultra high performance liquid chromatography triple quadrupole mass spectrometry was employed to determine their amounts The proportion preparations...