Abstract Background Staphylococcus aureus is a non-motile, gram positive, non-sporforming, facultative anaerobic microorganism. It one of the important bacteria as potential pathogen specifically for nosocomial infections. The sulfonamide derivative medicines are preferred to cure infection caused by S. due methicillin resistance. Methods Antimicrobial activity four derivatives have been investigated against 50 clinical isolates and tested using MIC disc diffusion methods. isolate which...

Abstract The title molecule, 4-(1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline (C15H15N3), was prepared and characterised by 1H-NMR, 13C-NMR, IR single-crystal X-ray diffraction. molecular geometry, vibrational frequencies gauge including atomic orbital (GIAO) 1H- 13C-NMR chemical shift values of the compound in ground state have been calculated using Hartree–Fock (HF) density functional theory (DFT) methods with 6–31G(d) basis sets, compared experimental data. results show that optimised...

Some imine derivatives ( 1a – 7d ) were synthesized using a rapid and an environmentally friendly method with reaction of aromatic aldehydes d amines 1 7 (in : molar ratio) in the presence <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math>-ethoxyethanol as wetting reagent (2 drops) under solvent-free conditions microwave heating.

A new convenient method for preparation of 2-substituted benzimidazoles and bis-benzimidazoles is presented.In this method, o-phenylenediamines were condensed with bisulfite adducts various aldehydes di-aldehydes under neat conditions by microwave heating.The results also compared synthesis conventional heating reflux.Structures the products confirmed infrared, 1 H-and 13 C-NMR spectroscopy.Short reaction times, good yields, easy purification products, mild are main advantages method.

Abstract The title molecule, 2‐(4‐chlorophenyl)‐1‐methyl‐1 H ‐benzo[ d ]imidazole (C 14 11 ClN 2 ), was prepared and characterized by 1 NMR, 13 C IR, single‐crystal X‐ray diffraction. molecular geometry, vibrational frequencies, gauge including atomic orbital (GIAO) NMR chemical shift values of the compound in ground state have been calculated using Hartree‐Fock (HF) density functional theory (DFT/B3LYP) method with 6‐31G(d) basis sets, compared experimental data. results show that optimized...

Abstract Microwave-assisted synthesis of some substituted open-chain and cyclic sulfamides, by amine-exchange reaction, was studied in a modified domestic microwave oven. Reaction times yields under radiation were compared with classical heating. Synthesis the sulfamides irradiation gave better desired compounds, considerably reduced reaction times, than those obtained [Supplementary materials are available for this article. Go to publisher's online edition Phosphorus, Sulfer, Silicon...

In the era of rapid technological advancements, artificial intelligence (AI) holds transformative potential for education, offering personalized learning, adaptive systems, and intelligent tutoring. However, successful integration AI into classrooms depends heavily on teachers' readiness literacy. This article explores urgent need comprehensive training programs educators, addressing current knowledge gaps ethical considerations use in education. It also discusses practical approaches to...

ABSTRACT Objectives To examine different types of restorative materials used in children as well primary and permanent teeth enamel when affected by erosive foods. Materials Method Buttermilk, fruit yoghurt, Coca‐cola, juice, Filtek Z‐250, Dyract Extra, Fuji II LC, IX tooth were used. Measurements performed on 1‐day, 1‐week, 1‐month, 3‐month, 6‐month time periods using ATR‐FTIR technique surface the specimens examined with SEM. Results Permanent showed least change among human samples...

The tetraethylammonium tetramethylammonium tetrabromocuprate(II), (hereafter, [(TEA)(TMA)CuBr4]) [(C2H5)4N][(CH3)4N][CuBr4], complex was synthesized and characterized by spectroscopic (IR), structural (XRD) electron paramagnetic resonance (EPR) technique. compound contains four isolated discrete moieties, i.e. two independent [(CH3)4N]+ cations, with one on a -4 axis the other central N atom 2z axis, [(C2H5)4N]]+ cation, mirror plane in trans conformation, distorted tetrahedral [CuBr4]2–...

The mechanism of acid-catalyzed hydrolysis a series p-substituted N,N′-diarylsulfamides was investigated in aqueous mineral acid solutions. Rate profiles, reaction activation parameters, catalytic order strong acids, solvent isotope effects, and analysis the kinetic data by excess acidity method suggest change from A2 to A1. While proceeds with an low regions, A1 takes place high concentrations. Copyright © 2013 John Wiley & Sons, Ltd.

In this study, 4-Methoxy-N-(3-phenylallylidene) aniline has been synthesized and characterized by FTIR NMR spectroscopic techniques. The optimized geometrical structure, vibrational frequencies shifts of title molecule were obtained using ab initio HF density functional method (B3LYP) with 6-31G* basis set. experimental calculated parameters compared each other. infrared (IR) data values B3LYP/6-31G* level theory. It was found to be a good correlation between data. addition, HOMO LUMO...

The title compound, C10H14N4O2S, exists in the amine tautomeric form. dihedral angle between benzene and thia­diazo­lidine rings is 66.54 (19)°. In crystal, mol­ecules are linked by N—H⋯O N—H⋯N hydrogen bonds into a layer parallel to ac plane. layers further C—H⋯O bonds.

Abstract The acid‐catalyzed hydrolyses of N ‐(4‐substituted‐arylsulf inyl)phthalimides were studied in aqueous solutions perchloric and sulfuric acids at 50.0 ± 0.1 hydrochloric acid 40.0 °C. Analysis the data by Cox–Yates excess acidity method substituent, temperature solvent isotope effects indicate hydrolysis an A 2 mechanism low acidity. At higher acidities a changeover to 1 is observed. Copyright­© 2001 John Wiley &amp; Sons, Ltd.

The acid-catalysed hydrolyses of some N-(para-substituted phenyl)propane-1,3-sultams have been studied in aqueous acidic solutions. rate maxima observed are shown to be consistent with an A-2 mechanism which extensive protonation the substrate occurs. Values pKBH+ for sultams determined.

The title compound, C10H10N2·C4H8N2O2, consists of hydrogen-bonded 2,3-di­methyl­quinoxaline and di­methyl­glyoxime mol­ecules. Both di­methyl­glyoximes are located on an inversion centre there two half-mol­ecules in the asymmetric unit. mol­ecules linked about centres to moiety by O—H⋯N hydrogen bonds (O⋯N 2.898 2.805 Å) form polymeric chains.

The acid‐catalyzed hydrolysis of a series 5‐substituted‐1 H ,3 ‐2,1,3‐benzothiadiazole 2,2‐dioxides has been investigated in aqueous solutions sulfuric, perchloric, and hydrochloric acid at 85.0 ± 0.05 °C. Analysis the kinetic data by excess acidity method, Arrhenius parameters, order catalytic effects strong acids, deuterium isotope effect, substituent effect have indicated that 5‐substituted benzosulfamides 1a , 1b 1c 1d occur with mechanistic switchover from A2 to A1 studied range: an...

Abstract The acid catalyzed hydrolyses of some cyclic disulfonimides, N-(4-substitutedphenyl)-o-benzenedisulfonimides (1a–d) have been studied in concentrated aqueous acidic solutions. Analysis the data by Excess Acidity Method, activation parameters, substituent, and solvent deuterium isotope effect are all indicate hydrolysis an A-1 mechanism range.

In the title Schiff base compound, C(13)H(9)Cl(2)NO, mol-ecule displays an E conformation about imine C=N double bond, with a dihedral angle of 8.09 (11)° between two benzene rings. crystal, mol-ecules are linked by single O-H⋯O hydrogen giving one-dimensional chains which extend along (100).

The reaction of sodium benzoxasulfamate (nbs) with cadmium(II) and mercury(II) sulfate in aqueous solution yield the novel complexes [Cd(nbs)2(H2O)4] (1) [Hg(nbs)2(H2O)3] (2), respectively. were characterized by elemental analyses, IR spectroscopy X-ray crystallography. Complex 1 is monomeric has an octahedral arrangement which N-donor nbs ligands occupy axial positions, while water oxygen atoms form equatorial plane. 2 polymeric shows a pentagonal bipyramidal achieved bridging HgN2O3 units...

The acid-catalyzed hydrolysis of 2-oxo-3-(p-substituted)-phenyl-5-methyl-1,2,3-oxathiazolidines (1) have been studied in 60% (v/v) 1,4 dioxane-aqueous solutions perchloric and hydrochloric acids at 10.0 ± 0.05°C. analysis the kinetic data by order catalytic effects acids, activation parameters, solvent isotope effect, substituent effect are all agreement with an A-2 mechanism range. Keywords: Acid-catalyzed hydrolysisamidosulfitesoxathiazolidinessubstituent Acknowledgments This work was...

The asymmetric unit of title compound, [Ni2(C4O4)(C7H10N2)4(H2O)2]C4O4·0.25H2O, contains one-half a squarate ligand, an uncoordinated dianion, two 2-(2-amino­ethyl)pyridine ligands and one aqua all coordinated to NiII ion. compound also 0.25 solvent water mol­ecules. ion has distorted octa­hedral geometry. ligand adopts μ-1,2 coordination mode, the intra­dimer NiII⋯NiII separation being 7.1442 (7) Å, while other acts as counter-anion. crystal structure is stabilized by inter­molecular O—H⋯O...