A5094225092- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Intergenerational Family Dynamics and Caregiving
- Autopsy Techniques and Outcomes
- Ocular Diseases and Behçet’s Syndrome
- Neurological and metabolic disorders
- Family and Disability Support Research
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Ophthalmology and Visual Impairment Studies
- Genetic Neurodegenerative Diseases
- Elder Abuse and Neglect
- AI in cancer detection
- Glaucoma and retinal disorders
- Artificial Intelligence in Healthcare and Education
- Diabetes and associated disorders
- Mitochondrial Function and Pathology
- Advancements in Transdermal Drug Delivery
University of Miami
2024-2025
Miami Dermatology and Laser Institute
2025
The current approach to minimize transplant-associated complications, including graft-versus-host disease (GVHD) includes long-term pharmacological immune suppression frequently accompanied by unwanted side effects. Advances in targeted immunotherapies regulating alloantigen responses the recipient continue reduce need for pan-immunosuppression. Here, vivo targeting of TNF superfamily receptor 25 (TNFRSF25) and high affinity IL-2 with a TL1A-Ig fusion protein low dose IL-2, respectively, was...
To investigate the corneal nerve damage in neurotrophic persistent epithelial defects by an vivo imaging system using multiphoton confocal microscopy (MCM) and calcitonin gene-related peptide (CGRP):GFP Tg mice. Corneal epithelium was scraped, followed administering a single dose of benzalkonium chloride (BAK) to develop defect. The defect imaged with fluorescein staining for up 24 hours, wound closure percentage (%, WCP) calculated. CGRP:GFP mice were used combination MCM acquire images...
Purpose of review Ocular surface inflammatory disorders (OSIDs), including allergic conjunctivitis, ocular graft-versus-host disease (oGVHD), and cicatrizing present significant clinical challenges due to complex immune modulation. Traditional therapies like corticosteroids have limitations, prompting the need for alternative treatments. This explores novel, steroid-sparing immunomodulatory options. Recent findings In recent years, evolved from broad-spectrum T-cell inhibitors such as...
Abstract: The ocular surface inflammatory disorders (OSIDs) comprise a group of conditions characterized by persistent inflammation the and adnexal tissues. Systemic autoimmune diseases hypersensitivity reactions cause them, and, if left untreated, can result in severe dry eye, corneal damage, vision loss. Ocular graft-versus-host disease (oGVHD) forms part umbrella. It is condition occurring after allogeneic hematopoietic stem cell or bone marrow transplantation, usually chronic disease....
To determine the efficacy of switching to intravitreal (IVT) faricimab in patients with treatment-resistant neovascular age-related macular degeneration (nAMD) and rates reversion original antivascular endothelial growth factor (anti-VEGF) therapy.
Khodor, Ali MD; Ruiz-Lozano, Raul E. Lanzo, Erin Vuong, Laurel N. Hedges, Thomas R. III Martin-Paez, Yosbelkys MD Author Information
The needs of family caregivers providing care to relatives with visual impairment are often dismissed, leading caregiver burden. Zarit Burden Interview (ZBI) can measure the burden caring for a member vision impairment. purpose this study is validate ZBI in Mexican patients was applied 137 acuity ≤ 20/200 best eye ≥ 6 months. ZBI's reliability determined using Cronbach's α and factor structure exploratory analysis (EFA, principal axis factoring promax rotation). Items loadings < 0.400 were...
To assess efficacy and safety of brolucizumab versus aflibercept in patients with diabetic macular edema (DME).