About
Contact & Profiles
A5102802577
Research Areas
- Prostate Cancer Treatment and Research
- Extracellular vesicles in disease
- Cell Adhesion Molecules Research
Thomas Jefferson University
2023
Highly aggressive, metastatic, neuroendocrine prostate cancer, which typically develops from cancer cells acquiring resistance to androgen deprivation therapy, is associated with limited treatment options and hence poor prognosis. We have previously demonstrated that the αVβ3 integrin over-expressed in cancer. now show LM609, a monoclonal antibody specifically targets human integrin, hinders growth of patient-derived xenografts vivo. Our group has recently identified novel binding partner,...
10.1016/j.matbio.2023.11.003
article
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cc-by-nc-nd
Matrix Biology
2023-11-11
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