A5040487171- Health and Lifestyle Studies
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Climate Change and Health Impacts
- Aging, Health, and Disability
- Dialysis and Renal Disease Management
- Knowledge Societies in the 21st Century
- Urological Disorders and Treatments
- Ecology and Vegetation Dynamics Studies
- Pharmaceutical Practices and Patient Outcomes
- Dermatology and Skin Diseases
- Educational Innovations and Technology
- Forest ecology and management
- Business, Innovation, and Economy
- COVID-19 and healthcare impacts
- Cancer Immunotherapy and Biomarkers
- Health and Medical Education
- Coffee research and impacts
- Chronic Disease Management Strategies
- Immunotherapy and Immune Responses
- HER2/EGFR in Cancer Research
- Lymphoma Diagnosis and Treatment
- Health disparities and outcomes
- Public Health and Environmental Issues
- Healthcare Systems and Public Health
University of Miami
2025
Institute for Health Metrics and Evaluation
2020-2024
University of Washington
2022-2024
Universidad Cooperativa de Colombia
2024
Instituto Nacional de Pediatria
2024
National Biodiversity Institute
2005-2022
National Health and Medical Research Council
2022
Hospital Universitario Fundación Alcorcón
2007-2021
Hospital Civil de Guadalajara
2020
Mario Negri Institute for Pharmacological Research
2020
Abstract Aim Tropical forests store 25% of global carbon and harbour 96% the world's tree species, but it is not clear whether this high biodiversity matters for storage. Few studies have teased apart relative importance forest attributes environmental drivers ecosystem functioning, no such study exists tropics. Location Neotropics. Methods We relate aboveground biomass ( AGB ) to (diversity structure) (annual rainfall soil fertility) using data from 144,000 trees, 2050 plots 59 sites. The...
Abstract A definitive cure for acute myeloid leukemia (AML) remains elusive. Inter and Intra-patient heterogeneity in antigen expression profiles is a major challenge AML treatment. Adapter CAR-T cell therapies utilize chimeric receptor (CAR) which binds to non-natural small molecule, turn can be attached soluble affinity domain that the tumor antigen. Decoupling cancer binding CAR engagement provides flexibility control directing therapy through dosing of adapter, improve safety decrease T...
It has been demonstrated that liver X receptors (LXR) play a significant role in cholesterol homeostasis. Agonists of LXR are expected to increase cellular efflux, lower LDL, and raise HDL levels. Screening natural product library plant extracts using LXR-SPA binding assay bioassay-guided fractionation number marine gorgonian led the isolation active compounds. These included acanthoic acid (1) alcohol (2), viperidone (3), polycarpol (4), rosacea (5), cycloartane derivative (6), new analogue...
Ior egf/r3, a neutralizing monoclonal antibody (mAb) against Epidermal Growth Factor Receptor (EGFR) was generated at the Cuban Institute of Oncology. Immunoscintigraphic studies in 148 patients with this 99-m Technetium (99Tc) labeled mAb, showed high sensitivity and specificity for vivo detection epithelial tumors. To study safety, pharmacokinetic immunogenicity ior egf/r3 doses, phase I clinical trial conducted. Nineteen advanced tumors received 4 mAb intravenous infusions 6 dose levels:...
Cedrela odorata L. is a native plant of the Amazon region. The bark used in folk remedies for treatment diarrhea, vomiting, fever and inflammation. Atopic dermatitis (AD) chronic, relapsing inflammatory skin disease accompanied by itching. It complex involving environmental factors genetic factors. In present study, anti‑inflammatory anti‑allergic effects C. methanol extract (COEE) on tumor necrosis factor (TNF)‑α interferon (IFN)‑γ‑stimulated HaCaT keratinocyte cells were investigated....
The city of Santa Marta faces a significant potable water shortage around 1600 liters daily, worsened by insufficient sources and outdated supply systems. Annual precipitation 362 mm exacerbates the problem. Groundwater, comprising 40% current supply, aims to alleviate this, yet doubts linger about source quality sustainability in with over half million residents. This study employed real-time IoT monitoring for pH, dissolved oxygen, conductivity, temperature. Data was Python-analyzed...
COVID-19 pandemic varies greatly and has different dynamics in every country, city, hospital Latin America. Obesity increases the risk of SARS-CoV-2 infection, it is one independent factors for most severe cases COVID-19. Currently, effective treatment against obesity available bariatric metabolic surgery (BMS), which further resolves or improves other like diabetes hypertension. Provide recommendations resumption elective BMS during pandemic. This document was created by IFSO-LAC Executive...
El estudio analiza el lipidograma y riesgo cardiovascular en pacientes de la Caja Salud Caminos (Tarija). Se evaluaron los niveles lípidos sangre para identificar patrones tendencias. La mayoría presentaron alterados, indicando enfermedades cardiovasculares. identificaron dislipidemias mixtas e hipoalfalipoproteinemia, sugiriendo necesidad seguimiento tratamiento adecuados.
Fragility is a multifactorial syndrome characterized by decrease in resistance, strength, and physiological function, making the patient more vulnerable dependent, thereby increasing mortality. This prevalent elderly patients with chronic kidney disease, particularly those undergoing hemodialysis.It documented (1) that prevalence of fragility phenotype adult disease who are not dialysis (14%) higher than general population (7%).
Aims & Objectives: Acute respiratory distress syndrome (ARDS) represents the most severe form of acute lung injury. The objective was to determine risk factors associated with mortality at PICU from Instituto Nacional de Pediatria, Mexico. Methods: Retrospective, observational, analytical and longitudinal study, period January 2018 December 2022. A descriptive analysis performed using percentage, mean, median, standard deviation, minimum maximum ranges. An inferential X2, Mann-Withney U...
La granulomatosis con poliangitis (GPA) es una vasculitis sistémica rara que afecta los vasos sanguíneos de pequeño y mediano calibre, está fuertemente asociada la presencia anticuerpos anticitoplasma neutrófi (ANCA). enfermedad se caracteriza por su impacto en el tracto respiratorio, tanto las vías aéreas superiores como inferiores, formación granulomas, puede comprometer sistema renal. Aunque no presenta predilección género, incidencia más alta entre 65 74 años. Los síntomas iniciales...
The genus Daphnopsis has been traditionally used as a purgative, diuretic, stimulant, and psoriasis treatment. In this study, the anti-AD (atopic dermatitis) activities of costaricensis EtOH extract (DCE) were investigated in an oxazolone (OX)-induced mouse model AD, anti-inflammatory effects its active compounds confirmed PI-sensitized or IgE/DNP-BSA-sensitized RBL-2H3 cells. DCE improved symptoms OX-induced inflammatory dermatitis (swelling, erythema, increased ear thickening) BALB/c mice...