O. O'Neill

ORCID: 0009-0004-9940-5135
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About
Contact & Profiles
Research Areas
  • Neuroscience and Neuropharmacology Research
  • Memory and Neural Mechanisms
  • Receptor Mechanisms and Signaling
  • Political Philosophy and Ethics
  • Ethics and Legal Issues in Pediatric Healthcare
  • Ethics in medical practice
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • International Labor and Employment Law
  • Ethics in Clinical Research
  • Gender Politics and Representation
  • Medieval Philosophy and Theology
  • Legal Education and Practice Innovations
  • Patient Dignity and Privacy
  • European Criminal Justice and Data Protection
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neural and Behavioral Psychology Studies
  • Stress Responses and Cortisol
  • Cybercrime and Law Enforcement Studies
  • Immune Cell Function and Interaction
  • Human Rights and Development
  • Policing Practices and Perceptions

University of Guelph
2023-2025

The Francis Crick Institute
2023

University of Cambridge
2003-2015

Newham College
2003

University of Essex
1984

Many accounts of informed consent in medical ethics claim that it is valuable because supports individual autonomy. Unfortunately there are many distinct conceptions autonomy, and their ethical importance varies. A better reason for taking seriously provides assurance patients others neither deceived nor coerced. Present debates about the relative generic specific (particularly use human tissues research secondary studies) do not address this issue squarely. Consent a propositional attitude,...

10.1136/jme.29.1.4 article EN Journal of Medical Ethics 2003-02-01

A contrast is often drawn between standard adult capacities for autonomy, which allow informed consent to be given or withheld, and patients' reduced capacities, demand paternalistic treatment. But patients may not radically different from the rest of us, in that all human autonomous action are limited. An adequate account paternalism role respect persons can play medical other practice has developed within an ethical theory does impose idealised picture unlimited autonomy but allows...

10.1136/jme.10.4.173 article EN Journal of Medical Ethics 1984-12-01

Consolidated long-term memories can be modified when destabilized at reactivation (RA). This must followed by an upregulation of protein synthesis to return the memory a stable state. Reconsolidation is suggested maintain relevance stored memories, preserving behavioral flexibility. Older or strongly encoded resist reconsolidation because biological boundary conditions and destabilization such more likely in presence prediction error reactivation. The neurotransmitter dopamine (DA), which...

10.1037/bne0000613 article EN Behavioral Neuroscience 2025-03-17

Abstract Background Memory updating is essential for integrating new information into existing representations. However, this process could become maladaptive in conditions like post-traumatic stress disorder (PTSD), when fear memories generalize to neutral contexts. Previously, we have shown that contextual memory malleability rats requires activation of M1 muscarinic acetylcholine receptors the dorsal hippocampus. Here, investigated involvement mechanism transfer other contexts using a...

10.1101/2024.06.02.597068 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-06-03

Memory updating is essential for integrating new information into existing representations. However, this process could become maladaptive in conditions like post-traumatic stress disorder (PTSD), when fear memories generalize to neutral contexts. Previously, we have shown that contextual memory malleability rats requires activation of M1 muscarinic acetylcholine receptors the dorsal hippocampus. Here, investigated involvement mechanism transfer other contexts using a novel paradigm....

10.1101/lm.054039.124 article EN Learning & Memory 2024-09-01

Justice and the Virtues Onora O'Neill Search for other works by this author on: Oxford Academic Google Scholar The American Journal of Jurisprudence, Volume 34, Issue 1, 1989, Pages 1–18, https://doi.org/10.1093/ajj/34.1.1 Published: 01 June 1989

10.1093/ajj/34.1.1 article EN The American Journal of Jurisprudence 1989-01-01
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