Xiaokui Zhu

ORCID: 0009-0005-2459-3095
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • SARS-CoV-2 and COVID-19 Research
  • Bacteriophages and microbial interactions
  • Microbial infections and disease research
  • Urinary Tract Infections Management
  • COVID-19 epidemiological studies
  • Bacterial Identification and Susceptibility Testing
  • Animal Virus Infections Studies
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bacterial biofilms and quorum sensing
  • Genomics and Phylogenetic Studies
  • Influenza Virus Research Studies
  • Long-Term Effects of COVID-19
  • COVID-19 and Mental Health

RMIT University
2025

Chengdu Medical College
2021-2022

Zunyi Medical University
2020

Hypervirulent Klebsiella pneumoniae (hvKp), one of the major community-acquired pathogens, can cause invasive infections such as liver abscess. In recent years, bacteriophages have been used in treatment K. pneumoniae, but characteristics phage-resistant bacteria produced process phage therapy need to be evaluated. this study, two Podoviridae phages, hvKpP1 and hvKpP2, were isolated characterized. vitro vivo experiments demonstrated that virulence resistant was significantly reduced compared...

10.3389/fmicb.2021.739319 article EN cc-by Frontiers in Microbiology 2021-10-06

In the post-COVID-19 era, dynamic spread of COVID-19 poses new challenges to epidemiological modelling, particularly due absence large-scale screening and growing complexity introduced by immune failure reinfections. This paper proposes an AEIHD (antibody-acquired, exposed, infected, hospitalised, deceased) model analyse predict transmission dynamics in era. removes susceptible compartment combines recovered vaccinated compartments into “antibody-acquired” compartment. It also introduces a...

10.3390/s25082507 article EN cc-by Sensors 2025-04-16

A single carbapenem-resistant, hypervirulent Klebsiella pneumoniae strain has attracted major public concern. The aim of the present study was to better understand antimicrobial resistance and genetic characteristics XJ-K1. XJ-K1 isolated from a urine specimen 69-year-old male patient in teaching hospital Shanghai, China, January 2018. Antimicrobial susceptibility testing, string test, whole-genome sequencing, bioinformatics analysis phylogenetic were performed this study. an extensively...

10.1016/j.jgar.2020.09.002 article EN cc-by-nc-nd Journal of Global Antimicrobial Resistance 2020-09-20

Carbapenem-resistant Klebsiella pneumoniae are distributed worldwide. This study aimed to characterize a hypervirulent tigecycline-resistant and carbapenem-resistant strain, XJ-K2, collected from patient's blood. We tested antimicrobial susceptibility, virulence, whole-genome sequencing (WGS) on strain XJ-K2. WGS data were used identify virulence resistance genes perform multilocus sequence typing (MLST) phylogenetic analysis. Three novel plasmids, including pLVPK-like plasmid (pXJ-K2-p1)...

10.1007/s10096-022-04512-6 article EN cc-by European Journal of Clinical Microbiology & Infectious Diseases 2022-11-02

Abstract Hypervirulent Klebsiella pneumoniae (hvKp) is one of the major community-acquired pathogens, which can cause invasive infections such as liver abscess. In recent years, bacteriophages have been used in treatment , but characteristics phage resistant bacteria produced process therapy need to be evaluated. this study, two podoviridae phages, hvKpP1 and hvKpP2, were isolated characterized. vitro vivo experiments demonstrated that virulence was significantly reduced compared with wild...

10.1101/2021.04.21.440873 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-04-22
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