A5035251480- Combustion and flame dynamics
- Venomous Animal Envenomation and Studies
- Noise Effects and Management
- Lipid Membrane Structure and Behavior
- Healthcare and Venom Research
- biodegradable polymer synthesis and properties
- SARS-CoV-2 and COVID-19 Research
- Vehicle Noise and Vibration Control
- Radiative Heat Transfer Studies
- Poisoning and overdose treatments
- Supramolecular Self-Assembly in Materials
- Synthesis and properties of polymers
- Advanced Combustion Engine Technologies
- Heme Oxygenase-1 and Carbon Monoxide
- Aerodynamics and Acoustics in Jet Flows
- Polymer Surface Interaction Studies
- Nanoparticle-Based Drug Delivery
- Acoustic Wave Phenomena Research
- Electronic Packaging and Soldering Technologies
- COVID-19 epidemiological studies
- Polymer composites and self-healing
- Rabies epidemiology and control
- Ion channel regulation and function
- Molecular Junctions and Nanostructures
- Advanced Polymer Synthesis and Characterization
University of California, Irvine
2015-2018
Stanford University
2016
University of San Diego
2014
Biochemical diversity of venom extracts often occurs within a small number shared protein families. Developing sequestrant capable broad-spectrum neutralization across various isoforms these families is necessary step in creating antivenom. Using directed synthetic evolution to optimize nanoparticle (NP) formulation sequestering and neutralizing venomous phospholipase A2 (PLA2), we demonstrate that sequestration biomacromolecules possible via single optimized NP formulation. Furthermore,...
The generation of indirect combustion noise by compositional inhomogeneities is examined theoretically. For this, the compact-nozzle theory Marble & Candel ( J. Sound Vib. , vol. 55 (2), 1977, pp. 225–243) extended to a multi-component gas mixture, and chemical potential function introduced as an additional acoustic source mechanism. Transfer functions for subcritical supercritical nozzle flows are derived, contribution compared entropy direct considering idealized downstream combustor...
Envenomings by snakebites constitute a serious and challenging global health issue. The mainstay in the therapy of snakebite envenomings is parenteral administration animal-derived antivenoms. Significantly, antivenoms are only partially effective control local tissue damage. A novel approach to mitigate progression damage that could complement antivenom proposed. We describe an abiotic hydrogel nanoparticle engineered bind modulate activity diverse array PLA2 3FTX isoforms found Elapidae...
Abstract Electrically conductive adhesive polymers offer many potential advantages relative to SnPb solders, including reduced toxicity, low cost, processing temperatures, and the ability make application‐specific formulations. Polymers generated from copper(I)‐catalyzed cycloaddition (CuAAC) reaction between multivalent azides alkynes have previously been identified as strong metal‐binding adhesives. Herein we demonstrate that performance of these materials can be remarkably improved by...
End-functionalized macromolecular starch reagents, prepared by reductive amination, were grafted onto a urethane-linked polyester-based backbone using copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry to produce novel amphiphilic hybrid graft copolymers. These copolymers represent the first examples of materials where pendant chains derived from biopolymers have been incorporated into host polymer grafting-to approach. The in good yields (63-90%) with high grafting efficiencies...