A5090578339- Parallel Computing and Optimization Techniques
- Fatigue and fracture mechanics
- Embedded Systems Design Techniques
- Analytical Chemistry and Chromatography
- Impact of Light on Environment and Health
- Interconnection Networks and Systems
- Engineering Applied Research
- Low-power high-performance VLSI design
- Advanced Data Storage Technologies
- Metallurgy and Material Forming
- Microstructure and Mechanical Properties of Steels
- Molecular Sensors and Ion Detection
- Semiconductor materials and devices
- Analytical Chemistry and Sensors
- Building Energy and Comfort Optimization
- Quantum Chromodynamics and Particle Interactions
- Distributed and Parallel Computing Systems
- Advancements in Semiconductor Devices and Circuit Design
- Synthetic Organic Chemistry Methods
- Mechanical Failure Analysis and Simulation
- Chemical Synthesis and Analysis
- Nuclear Physics and Applications
- Induction Heating and Inverter Technology
- Oral microbiology and periodontitis research
- Photonic Crystals and Applications
The University of Tokyo
2015-2025
University of the Ryukyus
1992-2025
Tohoku University Hospital
2023-2024
Tokyo Institute of Technology
1975-2024
Toyota Motor Corporation (Switzerland)
1999-2024
Toyota Central Research and Development Laboratories (Japan)
2006-2024
Yaskawa Electric (Japan)
1991-2024
The Nakamura Hajime Eastern Institute
2018-2023
Sanyo-Onoda City University
2023
Robert Bosch (Germany)
2023
1. Changes in excitability of the motor cortex induced by a transcranial magnetic stimulation (TMS) were examined simultaneous recording evoked corticospinal volley and compound surface electromyographic (EMG) response biceps brachii following paired‐pulse TMS five conscious subjects. The effects varying interstimulus interval (ISI) conditioning stimulus intensity also investigated. 2. A submotor threshold inhibited test responses at ISIs 2‐5 ms. supramotor 100‐200 Both these inhibitions...
is shown to be electrochemically active, with a maximum charge capacity of and discharge at . A total Li can extracted from , the first cycle efficiency regardless state charge. Larger charge-discharge obtained materials smaller particle size larger amount stacking faults. Composition structural analyses indicate that are removed both transitional metal layers material during charging. Results X-ray-absorption fine-structure measurements suggest valence Mn remains charging but reduced...
Recent reports indicate that copy number variations (CNVs) within the human genome contribute to nucleotide diversity a larger extent than single polymorphisms (SNPs). In addition, contribution of CNVs disease susceptibility may be greater previously expected, although complete understanding phenotypic consequences is incomplete. We have recently reported comprehensive view among 270 HapMap samples using high-density SNP genotyping arrays and BAC array CGH. this report, we describe novel...
Deficiency of osteoprotegerin (OPG), a soluble decoy receptor for activator nuclear factor-kappaB ligand (RANKL), in mice induces osteoporosis caused by enhanced bone resorption, but also accelerates formation. We examined whether formation is coupled with resorption OPG-deficient (OPG-/-) using risedronate, an inhibitor resorption. Histomorphometric analysis showed that formation-related parameters (e.g. mineral apposition rate and osteoblast surface/bone surface) OPG-/- sharply decreased...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorescence energy transfer between Ca2+ transport ATPase molecules in artificial membranesJ. M. Vanderkooi, A. Ierokomas, H. Nakamura, and MartonosiCite this: Biochemistry 1977, 16, 7, 1262–1267Publication Date (Print):April 5, 1977Publication History Published online1 May 2002Published inissue 5 April 1977https://pubs.acs.org/doi/10.1021/bi00626a003https://doi.org/10.1021/bi00626a003research-articleACS PublicationsRequest reuse...
3-D colloidal amorphous arrays prepared from two different submicron-sized silica particles, exhibit a specific structural color that remains unchanged during the alternation of viewing angle (see figure). The refractive index in photonic material changes identically all directions. This isotropic feature dielectric distribution leads to wavelength-selective light scattering. Detailed facts importance specialist readers are published as "Supporting Information". Such documents peer-reviewed,...
Microsomeswere prepared from predominantly white rabbit skeletal muscles essentially as described earlier (7).The muscle was homogenized in 4 volumes of 0.1 M KCl, 10 rnM imidazole, pH 7.3, for 2 5414
This study was undertaken to clarify the relationship among laser-induced plume ejected from keyhole, melt flows in molten pool, and formation mechanisms of spatters pool during 10 kW laser welding a pure titanium plate. High-speed video camera observation results showed that plumes occurred at intervals about 0.5 ms, maximum ejection velocity reached 250 m/s. Three-dimensional X-ray transmission in-situ weld with tungsten carbide tracers revealed flowed mainly along bottom keyhole tip rear...
SMARCA4 is a subunit of the switch/sucrose non‐fermentable (SWI/SNF) chromatin‐remodeling complex. An effective treatment for SMARCA4‐deficient non‐small cell lung carcinoma (NSCLC) has not yet been established. Correlations between response to immune checkpoint inhibitors and SWI/SNF complex have suggested, but little known about efficacy against NSCLC. A 43‐year‐old man underwent left upper lobe resection was diagnosed with adenocarcinoma. Two months after surgery, multiple metastases...
Advancements in 3D-Flash memory-layer-stacking technology has enabled density scaling that circumvents the lithography limitations which have prevented 2D-NAND Flash memory from [1]. Bit densities as high 5.95Gb/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> on a single die were recently reported [2], where 512Gb NAND was built 96 layers of memory. As increases, with increasing to 128 layers, higher bit can be achieved by adopting...
Addition of the silicon–boron bond across carbon–carbon triple bonds, i.e. silaboration is most effectively catalysed by a palladium(0)–tert-alkyl isocyanide complex to give (Z)-1-boryl-2-silyl alkenes with high regio- and stereo-selectivity, which are useful for synthesis stereodefined alkenylsilanes.
Abstract Objective Articular chondrocyte senescence is responsible, at least in part, for the increased incidence of osteoarthritis (OA) with age. Recently, it was suggested that caveolin 1, a 21–24‐kd membrane protein, participates premature cellular senescence. Caveolin 1 principal structural component caveolae, vesicular invaginations plasma membrane. This study undertaken to investigate whether catabolic factors oxidative stress and interleukin‐1β (IL‐1β) induce features articular...
Abstract Peripheral T lymphocytes undergo activation by antigenic stimulation and function in hypoxic areas of inflammation. We demonstrated CD3-positive human cells accumulating inflammatory tissue expression the hypoxia-inducible factor-1α (HIF-1α), indicating a role hypoxia-mediated signals regulation cell function. Surprisingly, accumulation HIF-1α required not only hypoxia but also TCR/CD3-mediated activation. Moreover, repressed activation-induced death (AICD) TCR/CD3 stimulation,...
Peripheral T cells encounter rapid decrease in oxygen tension because they are activated by Ag recognition and migrate into inflammatory sites or tumors. Activated cells, therefore, thought to have such machineries that enable them adapt hypoxic conditions execute immune regulation situ. We recently shown survival of CD3-engaged human peripheral blood is prolonged under hypoxia-inducible factor-1 (HIF-1) its target gene product adrenomedullin play a critical role for the process. It also...
The exploitation of a new host by parasite may result in host-race formation or speciation. A brood parasitic bird, the common cuckoo, is divided into races, each characterized egg mimicry different species. Microsatellite DNA markers were used to examine cuckoo mating patterns and usage an area where has been recently colonized. Female cuckoos show strong preferences, but individual males mate with females that lay nests hosts. specialization lead evolution sex-linked traits such as...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective intramolecular bis-silylation of alkenes promoted by a palladium-isocyanide catalyst leading to polyol synthesisMasahiro Murakami, Michinori Suginome, Kenzo Fujimoto, Hiroshi Nakamura, Pher G. Andersson, and Yoshihiko ItoCite this: J. Am. Chem. Soc. 1993, 115, 15, 6487–6498Publication Date (Print):July 1, 1993Publication History Published online1 May 2002Published inissue 1 July 1993https://doi.org/10.1021/ja00068a003RIGHTS &...
Abstract Transcription factor hypoxia-inducible (HIF)-1 protein accumulates and activates the transcription of genes that are fundamental importance for oxygen homeostasis – including involved in energy metabolism, angiogenesis, vasomotor control, apoptosis, proliferation, matrix production under hypoxic conditions. We speculated HIF-1α may have an important role chondrocyte viability as a cell survival during progression osteoarthritis (OA). The expression mRNA human OA cartilage samples...
Rate capability of Li-excess Mn-based layered cathode materials is improved by treating with . After treatment, discharge capacity as high 230 mAh/g can be obtained at a rate 300 mA/g The improvement attributed to the modification surface material into spinel-like structure suggested Raman spectroscopy and electrochemical charge–discharge. X-ray diffraction results show no change in bulk lattice parameters, indicating that structural only on active material. Chemical analyses both lithium...