About
Contact & Profiles
A5062002978
Research Areas
- Retinal Development and Disorders
- Probiotics and Fermented Foods
- Cancer Mechanisms and Therapy
- Drug Transport and Resistance Mechanisms
- Natural Compounds in Disease Treatment
- Biopolymer Synthesis and Applications
- Natural product bioactivities and synthesis
- Ocular Oncology and Treatments
- Milk Quality and Mastitis in Dairy Cows
Wenzhou Medical University
2007-2024
Second Affiliated Hospital of Jilin University
2024
10.1007/s43450-024-00529-4
article
EN
Revista Brasileira de Farmacognosia
2024-03-29
Lung cancer is one of the leading causes death. Celastrol a natural product that has shown anticancer activity but not yet been applied in clinical settings due to its narrow therapeutic window. In this study, we discovered celastrol stimulates an abnormal rise reactive oxygen species (ROS) level lung cells and ROS scavenger N-acetylcysteine (NAC) could counteract cell death caused by celastrol. At same time, upregulated expression cytoprotective transcription factor Nrf2 downstream...
10.1021/acsomega.4c06152
article
EN
cc-by-nc-nd
ACS Omega
2024-10-15
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