A5031479328- Lipoproteins and Cardiovascular Health
- Liver Disease Diagnosis and Treatment
- Nutritional Studies and Diet
- Cancer-related molecular mechanisms research
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Birth, Development, and Health
- Peripheral Artery Disease Management
- Diet and metabolism studies
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Vitamin K Research Studies
- Gout, Hyperuricemia, Uric Acid
- Heavy Metal Exposure and Toxicity
- Complement system in diseases
- Advanced MIMO Systems Optimization
- Advanced Decision-Making Techniques
- Pulmonary Hypertension Research and Treatments
- MicroRNA in disease regulation
- Calcium Carbonate Crystallization and Inhibition
- Phytochemistry and Bioactivity Studies
- Ideological and Political Education
- Neuroscience of respiration and sleep
Zhujiang Hospital
2024-2025
Southern Medical University
2024-2025
Sun Yat-sen Memorial Hospital
2020-2024
Sun Yat-sen University
2020-2024
Inner Mongolia Electric Power (China)
2024
Nanchang University
2017-2018
Second Affiliated Hospital of Nanchang University
2017-2018
Beijing Jiaotong University
2016
Beihang University
2007
Harbin University
2003
Emerging evidence indicates that alteration of gut microbiota plays an important role in chronic kidney disease (CKD)-related vascular calcification (VC). We aimed to investigate the specific and underlying mechanism involved CKD-VC. identified increased abundance Prevotella copri (P. copri) feces CKD rats (induced by using 5/6 nephrectomy followed a high calcium phosphate diet) with aortic via amplicon sequencing 16S rRNA genes. In patients CKD, we further confirmed positive correlation...
Abstract Background It remains unclear whether triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, is prospectively associated with incident peripheral arterial disease (PAD). Methods We included 12,320 Atherosclerosis Risk in Communities Study participants (aged 54.3 ± 5.7 years) free history PAD at baseline (visit 1: 1987–1989). The TyG index was determined using ln (fasting triglycerides [mg/dL] × fasting glucose [mg/dL]/2), and measured 5 visits between 1987 2013....
Background: Remnant cholesterol (RC) contributes to residual risk of atherosclerotic cardiovascular disease, but population-based evidence on the prospective relationship between RC and coronary artery calcium (CAC) progression is rare. Methods: We pooled data obtained from 6544 disease–free individuals CARDIA study (Coronary Artery Risk Development in Young Adults; n=2635) MESA (Multi-Ethnic Study Atherosclerosis; n=3909), with a mean±SD age 47.2±19.8 years; 3019 (46.1%) were men who...
Abstract Background Remnant cholesterol (RC) is implicated in the risk of cardiovascular disease. However, comprehensive population-based studies elucidating its association with aortic valve calcium (AVC) progression are limited, rendering precise role AVC ambiguous. Methods From Multi-Ethnic Study Atherosclerosis database, we included 5597 individuals (61.8 ± 10.1 years and 47.5% men) without atherosclerotic disease at baseline for analysis. RC was calculated as total minus high-density...
Objective: To investigate whether low-carbohydrate diets (LCDs) were associated with coronary artery calcium (CAC) progression. Approach and Results: We included the participants who completed computed tomography assessment of baseline CAC in 2000 to 2001 (year 15) follow-up 20 or 25) food frequency questionnaire (years 0, 7, 20) CARDIA study (Coronary Artery Risk Development Young Adults). progression was defined as >0 at among 0 an annualized change 10 percent ≥10% for those...
The study aimed to assess the associations of physical activity (PA) trajectories across a 25-year span with coronary artery calcium (CAC) progression, and subsequent risk cardiovascular disease (CVD) events.We included 2497 participants from Coronary Artery Disease Risk Development in Young Adults who had computed tomography-assessment CAC at baseline (year 15: 2000-2001) follow-up 20 or 25) least three measures PA year 0 25. Long-term were determined by latent class modelling using...
Background: To investigate whether obesity with or without metabolic syndrome is prospectively associated coronary artery calcium (CAC) progression and incident cardiovascular disease events. Methods: A total of 1730 participants from the CARDIA study (Coronary Artery Risk Development in Young Adults) were included (age, 40.1±3.6 years; 38.3% men), who completed computed tomography CAC at baseline (year 15: 2000–2001) follow-up 20 25). Metabolically healthy (MHO) was defined as body mass...
Background Non-alcoholic fatty liver disease (NAFLD) has emerged as a predominant driver of chronic globally and is associated with increased cardiovascular morbidity mortality. However, the association between NAFLD calcific aortic valve remains unclear. We aimed to prospectively investigate incident calcification (AVC), well its genetic relationship stenosis (CAVS). Methods A post hoc analysis was conducted on 4226 participants from Multi-Ethnic Study Atherosclerosis (MESA) database....
Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodeling, culminating in stenosis, heart failure, and ultimately premature death. Ferroptosis has been hypothesized contribute the pathogenesis of CAVD. We aimed study association between ferroptosis genes CAVD reveal potential roles CAVD-related differentially expressed (DEGs) were identified via bioinformatic analysis Datasets...
Excess aldosterone is implicated in vascular calcification (VC), but the mechanism by which aldosterone-MR (mineralocorticoid receptor) complex promotes VC unclear. Emerging evidence indicates that long-noncoding RNA H19 (H19) plays a critical role VC. We examined whether aldosterone-induced osteogenic differentiation of smooth muscle cells (VSMCs) through epigenetic modification Runx2 (runt-related transcription factor-2) MR-dependent manner.We induced vivo rat model chronic kidney disease...
Homocysteine-lowering intervention with folate was recently shown to be able increase day-night difference of blood pressure (BP) in humans indicating a potential relationship between homocysteine and circadian BP variation. We thus sought investigate the association plasma total level (tHcy) variation hypertensive adults.We enrolled 244 eligible dipping 249 nondipping status adults from 560 who were randomly sampled 5,233 Chinese received ambulatory monitoring (ABPM). further 390 CC/CT...
The pervasive increasing mobile devices and explosively data traffic pose imminent challenges on wireless network design. Device-to-device (D2D) communication is envisioned to play a key role in the fifth generation cellular networks efficiently support much larger more diverse set of devices. This paper investigates mode selection resource allocation for D2D communications with dynamic user arrivals departures. We formulate optimal control problem minimize average energy consumption flow...
Abstract An experimental analysis was conducted on the cause of cracking in angle steel a 220 kV transmission tower using macroscopic inspection, chemical composition analysis, microstructure and other testing methods. The results show that did not have groove before welding with filler material at notch bending position. Severe incomplete penetration defects were formed during process, resulting large stress concentration defect site. This is main reason for its corrosion fracture. It...
The corrosion causes of a 220kV transmission tower grounding flat steel were experimentally analyzed by macroscopic inspection, chemical composition analysis, microscopic structure product morphology and energy spectrum, galvanized layer thickness test, soil physical property other test methods. results indicate that the combined effect electrochemical stray current has resulted in development severe damage, which ultimately led to failure steel. Furthermore, requisite protective measures...
Intraindividual variability in lipid profiles is recognized as a potential predictor of cardiovascular events. However, the influence early adulthood profile along with mean levels on future coronary artery calcium (CAC) incidence remains unclear.
Individuals with high blood pressure (BP) have varying risks of cardiovascular events due to other coexisting factors. We aimed identify the predictors long-term absence coronary artery calcium (CAC) in individuals BP, which is an indicator healthy arterial aging and can guide preventive strategies.We analyzed data from participants BP (≥120/80 mm Hg) Multi-Ethnic Study Atherosclerosis who had baseline CAC = 0 underwent a second scanning after 10 years. used multivariable logistic regression...
Abstract Background It remains unclear whether triglyceride-glucose (TyG) index, a surrogate marker of IR, was prospectively associated with incident PAD. Methods We included 12573 ARIC (Atherosclerosis Risk in Communities Study) participants free PAD at baseline (1987–1989). The TyG index determined using ln(fasting triglycerides [mg/dL] × fasting glucose [mg/dL]/2), and measured during 5 visits between 1987 2013. Incident defined as the first hospitalization diagnosis. quantified...