A5025916363- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Protease and Inhibitor Mechanisms
- Blood Coagulation and Thrombosis Mechanisms
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Olfactory and Sensory Function Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Multiple Sclerosis Research Studies
- Endometriosis Research and Treatment
- Pregnancy-related medical research
- Antioxidant Activity and Oxidative Stress
- Neuroscience of respiration and sleep
- Electrospun Nanofibers in Biomedical Applications
- Sleep and Wakefulness Research
- Ophthalmology and Eye Disorders
- Cardiovascular Syncope and Autonomic Disorders
- Dermatology and Skin Diseases
- Sympathectomy and Hyperhidrosis Treatments
- Cancer-related gene regulation
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Disease and Adiposity
- Personality Disorders and Psychopathology
- Pulmonary Hypertension Research and Treatments
HonorHealth
2024-2025
Mayo Clinic in Arizona
2019-2024
Thomas Jefferson University
2024
Cedars-Sinai Medical Center
2024
University of Colorado Anschutz Medical Campus
2024
Duke University
2024
Stanford University
2024
Mayo Clinic in Florida
2018
WinnMed
2018
University of North Carolina at Chapel Hill
2004-2011
Acute and persistent post-traumatic headache are often debilitating consequences of traumatic brain injury. Underlying physiological mechanisms its persistence remain unknown, there currently no approved therapies for these conditions. Post-traumatic presents with a migraine-like phenotype. As calcitonin-gene related peptide promotes migraine headache, we explored the efficacy timing intervention an anti- monoclonal antibody in novel preclinical models acute following mild injury event...
Overuse of symptomatic (i.e., acute) medications is common among those with chronic migraine. It associated developing frequent headaches, medication side effects, and reduced quality life. The optimal treatment strategy for patients who have migraine overuse (CMMO) has long been debated. study objective was to determine whether preventive therapy without switching or limiting the frequency overused noninferior from an alternative that could be used on ≤2 d/wk.The Medication Treatment...
This review focuses on the challenges of diagnosing and treating spontaneous intracranial hypotension (SIH), a condition caused by spinal CSF leakage. It emphasizes need for increased awareness advocates early thoughtful use empirical epidural blood patches (EBPs) in suspected cases.
Background Women with endometriosis are more likely to have migraine. The mechanisms underlying this co-morbidity unknown. Prolactin, a neurohormone secreted and released into circulation from the anterior pituitary, can sensitize sensory neurons female, but not male, rodents, monkeys human donors. Methods We used syngeneic model of determine whether elevated prolactin levels trigeminal ganglion increase vulnerability migraine pain. Results Mice endometriotic lesions showed increased serum...
Medication overuse is a significant issue that complicates the treatment of headache disorders. The most effective medications for acute migraine all have capacity to induce medication (MOH). Novel migraine-specific treatments are being developed. However, because mechanism(s) underlying not well understood, it difficult predict whether any particular will MOH in susceptible individuals. LY573144 (lasmiditan), 5-HT1F receptor agonist, has recently been shown be phase 3 trials. aim this study...
We examined whether dialectical behavior therapy (DBT) was feasible and effective in multiple sclerosis (MS). A convenience sample of 20 patients with anxiety or depression symptoms received either DBT (n = 10) standard medical care 10). The protocol found to be the MS population studied (e.g., good retention acceptability). For group, significant improvements were demonstrated self-rated clinician-rated depressive symptoms, general psychopathology quality life. In contrast, group retained...
Abstract Migraine and sleep disorders are common co-morbidities. Patients frequently link their to migraine attacks suggesting a potential causal relationship between these conditions. However, whether pain promotes or disrupts disruption can increase the risk of remains unknown. We assessed impact periorbital allodynia, measure consistent with migraine-like pain, from multiple preclinical models on quantity quality. Additionally, we evaluated possible consequences deprivation in promoting...