Daniela Parra
- Health Policy Implementation Science
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac Imaging and Diagnostics
- COVID-19 Clinical Research Studies
- Clinical practice guidelines implementation
- Acute Myocardial Infarction Research
- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- PARP inhibition in cancer therapy
- Peripheral Artery Disease Management
- SARS-CoV-2 and COVID-19 Research
- Coronary Interventions and Diagnostics
- Birth, Development, and Health
- Public Health and Social Inequalities
- Primary Care and Health Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Neurobiology and Insect Physiology Research
- Diet and metabolism studies
- Protease and Inhibitor Mechanisms
- Long-Term Effects of COVID-19
- Healthcare Systems and Technology
- Venous Thromboembolism Diagnosis and Management
- Philosophy and History of Science
- Atrial Fibrillation Management and Outcomes
- Evolution and Science Education
Clínica CES
2022-2024
Hofstra University
2016
Northwell Health
2016
University of Chile
2005-2011
University of Talca
2009
Abstract Background Metformin has antiviral activity against RNA viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be suppression of protein translation via targeting the host mechanistic target rapamycin pathway. In COVID-OUT randomized trial for outpatient disease 2019 (COVID-19), metformin reduced odds hospitalizations/death through 28 days by 58%, emergency department visits/hospitalizations/death 14 42%, and long COVID 10 months...
The vomeronasal system is crucial for social and sexual communication in mammals. Two populations of sensory neurons, each expressing Gαi2 or Gαo proteins, send projections to glomeruli the rostral caudal accessory olfactory bulb, rAOB cAOB, respectively. In rodents, Gαi2- Gαo-expressing pathways have shown differential responses small/volatile vs. large/non-volatile semiochemicals, Moreover, early gene expression suggests predominant activation cAOB neurons aggressive contexts, We recently...
Thrombosis is a result of the interaction between predisposing genetic polymorphisms and acquired risk factors. The two prothrombotic which are most frequently associated with thrombosis factor V (FV) Leiden prothrombin (PT) G20210A mutation. objective this work was to investigate prevalence both factors in central-south region Chile. Determination frequency carried out by means analysis 1200 healthy, non-native individuals. mutation FV found 1.25% population PT 1.33%. None individuals were...
Schizophrenia is a severe mental illness characterized by disconnection from reality, significantly impacting person's ability to function and leading substantial disability. While the exact causes of schizophrenia remain unclear, it understood result combination genetic, neurochemical, environmental factors. The heritability high, although does not follow Mendelian patterns. symptomatology includes both positive symptoms such as hallucinations, delusions, psychotic episodes, negative like...
In a recent commentary, Nespolo (2003) makes reference to his personal experience as exattendant the course of evolution imparted by Dr. Humberto Maturana and Jorge Mpodozis at Facultad de Ciencias Universidad Chile construct negative criticism Chilean undergraduate teaching evolution. As ex-attendants mentioned we have had an that is directly comparable Nespolo. Here wish point out our opinion regarding this course, which markedly different. First, it caricature state in natural selection...